Sodium adenosine triphosphate

Sodium adenosine triphosphate is a cardiac agent that helps stabilize the energy processes of metabolism.

[1], [2], [3],

Indications of the sodium adenosine triphosphate

It is used in combination with other medicines to help people with atrophy or muscular dystrophy, and also to people with pathologies in which spasms in the peripheral vascular organs are observed (this includes Reynaud's syndrome, intermittent claudication, and with it Burger's disease).

The medicine is also used to prevent the development of paroxysmal supraventricular tachycardia.

Medication, among other things, can also be used to stimulate labor.

The drug ATP-Forte is prescribed for people who have a degeneration of the pigment type in the retina, which is hereditary (central or peripheral, and in addition a mixed form of the disease).

[4], [5], [6], [7], [8]

Release form

The release is carried out in the form of a parenteral drug solution, in ampoules with a volume of 1 ml. Inside a separate box there are 10 such ampoules.

[9], [10], [11], [12], [13], [14]

Pharmacodynamics

Inside the organism, the active component undergoes hydrolysis, which results in the formation of an ATP element, which is further metabolized to the ADP substance, as well as to the phosphate of the inorganic type due to the interaction that occurs with the actomyosin element. During metabolism, ATP releases the energy used by the body to perform binding processes for various components and to perform mechanical functions.

As a result of using drugs, there is a decrease in the smooth muscle tone, stabilization of the processes of carrying out nervous responses inside the vegetative nodes, and at the same time moving the exciting pulse from the region of the vagus nerve to the heart. Metabolism of the ATP element causes a slight suppression of the Purkinje fibers together with the sinus atrial node.

[15]

Dosing and administration

The drug is administered parenterally. Basically this involves an IM procedure, but in severe forms of impairment (eg, prevention of supraventricular tachyarrhythmias), the solution is administered by IV injection. Duration of therapy is assigned to each patient separately - it is determined by the treating doctor.

For adults suffering from muscle dystrophy or problems with peripheral blood flow, they often prescribe the administration of 1 ml of the solution once a day for 2 days, and then they start to administer the drug in the same way and in the same dosage, but twice already per day. It is allowed to prescribe the introduction of 2 ml once a day from the first day of the course - with the correction of dosage in the future is not required.

This course often lasts 30-40 days. If necessary, after the expiration of 1-2 months after the completion of the previous course, a second treatment may be prescribed.

People suffering from degeneration of the retina pigmentary nature (having a hereditary genesis), it is necessary to inject 5 ml of solution in / m way twice a day. The gap between these procedures is about 6-8 hours.

This course is mainly continued for 15 days. If necessary, it can be repeated at intervals of 8-12 months.

To prevent supraventricular tachyarrhythmia, often carry out intravenous injection of 1-2 ml of the solution. The entire procedure should last about 5-10 seconds. In the absence of the required medicinal effect, it is possible to inject the solution repeatedly, after 2-3 minutes.

[29], [30], [31], [32], [33]

Use of the sodium adenosine triphosphate during pregnancy

There is no information on the safety of drug use by pregnant women or lactating women. In pregnancy, he can only appoint a doctor, taking into account the ratio of the benefits for the woman and the risk to the fetus.

Contraindications

The main contraindications:

• presence of severe intolerance in relation to the elements of the medication;
• patients who have an acute stage of myocardial infarction;
• It is forbidden for therapy to children under 18 years of age, because there is no adequate information on the effectiveness, as well as the safety of the use of the solution in this group of patients.

[16], [17], [18], [19], [20], [21]

Side effects of the sodium adenosine triphosphate

Often the medicine is transferred without complications.

Sometimes as a result of the / m introduction of the drug there are headaches and tachycardia, and in addition there is an increased diuresis.

As a result, intravenous injection of the drug sometimes caused vomiting with nausea, headaches, and at the same time hyperemia in the upper half of the body, as well as face.

In addition, you can expect the appearance of allergy symptoms.

If the patient exhibits significant side effects, the use of the drug should be canceled.

[22], [23], [24], [25], [26], [27], [28]

Interactions with other drugs

It is forbidden to combine the medicine with cardiac glycosides in large portions.

[34], [35], [36]

Storage conditions

Sodium adenosine triphosphate should be kept in a dark place where moisture does not reach. Temperature values are within 3-5 ° C.

[37], [38], [39]

Shelf life

Sodium adenosine triphosphate can be used for 1.5 years from the date of manufacture of the drug solution.

[40], [41], [42], [43]