Smecta

Dioctahedral smectite, the main active ingredient in Smecta, is a natural mineral and is a clay mineral from the smectite group. It has the ability to adsorb toxins, water and other substances in the gastrointestinal tract, which makes it effective in the treatment of various gastrointestinal disorders.

Smecta containing dioctahedral smectite is often used to treat diarrhea and symptoms associated with irritation of the gastrointestinal mucosa. Its mechanism of action is that smectite forms a protective coating on the surface of the intestinal mucosa, preventing contact with toxins and other irritants and reducing the rate at which food passes through the gastrointestinal tract.

It reduces the frequency and intensity of diarrhea, decreases bloating and reduces abdominal pain. In addition, Smecta can be used for symptomatic treatment of other gastrointestinal disorders such as heartburn and dyspepsia.

The drug is usually available as a powder for preparing a suspension or as ready-made sachets or tablets. It is usually taken orally by dissolving the contents of the sachet or tablet in water and drinking. The dosage and duration of administration may vary depending on the age of the patient and the characteristics of the disease.

Indications Smecta

1. Diarrhea: Smecta is often used to treat acute and chronic diarrhea. It helps to reduce the frequency and intensity of diarrhea and restore water-electrolyte balance in the body.
2. Abdominal bloating and dyspepsia: The drug may be used for symptomatic treatment of abdominal bloating, bloating, noises and other discomfort associated with dyspepsia (digestive disorders).
3. Heartburn and symptoms of gastroesophageal reflux disease (GERD): Smecta may help reduce symptoms of heartburn and other manifestations of GERD, such as a burning sensation in the chest and acid regurgitation.
4. Food poisoning: The drug can be an effective treatment for food poisoning or contact with toxic substances, as it is able to adsorb toxins and facilitate their elimination from the body.
5. Irritable bowel syndrome (IBS): In some patients with IBS, symptoms such as abdominal pain and diarrhea may improve with Smecta.

Release form

• Powder for preparation of suspension for oral administration: This is the most common form of Smecta release. The powder is packaged in single-dose packets, each of which is designed to be dissolved in a small amount of water before use. It is available in a variety of flavors (e.g., vanilla, orange) to improve palatability and ease of ingestion, especially in children.
• Ready-to-usesuspension: In some countries, Smecta may be available as a ready-to-use suspension, making it even more convenient to use, especially outside the home or when it is not possible to prepare a suspension.

Pharmacodynamics

Its pharmacodynamics is based on its ability to bind and remove from the body toxins, bacteria, viruses and other harmful substances from the gastrointestinal tract. Smecta has adsorbing and protective action, forming a protective film on the surface of the intestinal mucosa.

Smecta is not absorbed into the systemic bloodstream, which makes it safe for use in patients of any age, including children and pregnant women. It has an antidiarrheal effect, reducing the amount of fluid in the intestine and improving the consistency of feces.

Pharmacokinetics

1. Absorption: Smecta is not absorbed from the gastrointestinal tract into the systemic circulation, but remains inside the intestine. Its molecules form a gel in combination with water and form a protective layer on the intestinal mucosa.
2. Metabolism and excretion: Since smectite is not absorbed into the blood, there is no metabolism or excretion. It leaves the body with the feces.
3. Speed of action: Smecta has antidiarrheal action due to the formation of a gel that absorbs and removes toxins and infectious agents from the intestine and protects the mucous membrane from irritation.
4. Time of action: Smecta begins to take effect within a short time after ingestion and usually has an effect within a few hours.

Dosing and administration

For adults and children over 12 years of age:

• For acute diarrhea: The standard dose is 3 sachets per day.
• For chronic conditions: Dosage may be reduced to 1-2 sachets per day depending on doctor's recommendations.

For children from 1 to 12 years old:

• For acute diarrhea: The usual dose is 2-3 sachets per day. The dosage may be adjusted depending on the weight and age of the child.
• For very young children, the dosage can be adapted and the use of Smecta should be under the direct supervision of a doctor.

For infants up to 1 year of age:

• For acute diarrhea: Usually 1 sachet per day is recommended. However, infants should be treated under strict medical supervision.

Method of preparation and reception:

• The contents of the sachet are dissolved in a small amount of water (about 50 ml for children and 100 ml for adults) or can be added to soft food (compote, mashed potatoes) to facilitate ingestion, especially in children.
• For best results, it is recommended to take dissolved Smecta separately from other medications (at least 1-2 hours before or after taking other medications), as it may affect their absorption.
• In acute diarrhea, it is also important to ensure adequate replenishment of fluid and electrolytes in the body.

It's important to remember:

• Do not stop treatment with Smecta immediately after the disappearance of symptoms, it is recommended to continue taking it for several days to stabilize the condition.
• If symptoms persist for more than a few days or worsen, you should see a doctor.

Use Smecta during pregnancy

Smecta is generally considered safe for use during pregnancy, provided it is used as directed and under the supervision of a doctor.

Contraindications

1. Hypersensitivity: People with known hypersensitivity to smectite or any other component of the drug are not recommended to use Smecta due to the risk of allergic reactions.
2. Intestinal obstruction: Smecta is not a treatment for intestinal obstruction and may be ineffective or even harmful in this condition.
3. Glucose-galactose malabsorption syndrome: The drug contains glucose, therefore it should be used with caution in patients with rare hereditary glucose-galactose malabsorption disorder.
4. Diabetes: Smecta may contain sugar, so diabetic patients should take this into account when using it and, if necessary, adjust the dosage of insulin or hypoglycemic drugs.
5. Hepatic insufficiency: In patients with severehepatic dysfunction, changes in drug handling may be observed, therefore, Smekta administration requires caution in this condition.
6. Patients with Malabsorption Syndrome: In patients with malabsorption syndrome (e.g. Celiac disease) Smecta may worsen symptoms and should be used with caution.
7. Pregnancy and breastfeeding: In general, Smecta is considered safe for use during pregnancy and breastfeeding, but it is important to consult a doctor before use in these cases.

Side effects Smecta

1. Constipation: Occasionally, Smekta may cause constipation or difficulty stooling. This effect usually goes away after you stop taking the medicine.
2. Digestive disorders: Some patients may experience a feeling of heaviness in the stomach or unusual feelings in the abdominal area.
3. Allergic Reactions: Although allergic reactions to Smecta are rare, some people may develop an allergic skin rash, itching, or hives. In case of allergic signs, you should stop using the drug and consult a doctor.
4. Changes in stool composition: The use of Smecta may cause changes in the consistency and color of the stool in some patients. This is usually temporary and not dangerous.
5. Interaction with other medicines: Smecta may interact with some other medicines, reducing their effectiveness. Therefore, it is important to tell your doctor about all the medicines you are taking before you start taking Smecta.

Overdose

Smecta overdose usually does not lead to serious consequences due to its low systemic availability and lack of absorption into the blood. However, if the recommended doses are exceeded, unpleasant symptoms such as constipation, abdominal pain, stomach discomfort and rumbling may occur.

Interactions with other drugs

Smecta has minimal potential to interact with other medicines because of its mechanism of action, which is based on the creation of a protective layer on the intestinal mucosa. This layer usually does not affect the absorption or metabolism of other orally administered drugs.

However, in order to prevent possible interactions, it is recommended to take other medicinal products at least 1-2 hours before or after taking Smecta. This avoids possible reduction in the effectiveness of other drugs due to the formation of a protective layer on the intestinal mucosa.