Sedavit

A sedative drug based on plant components is Sedavit. Let's consider the pharmacological features of the drug and the rules for its use.

The complex composition of Sedavit provides an anxiolytic effect. This allows it to be used for severe nervous disorders and stress. The composition of the drug includes valerian roots, hawthorn fruits, St. John's wort, hop cones and peppermint leaves. Biologically active components have a positive effect on the functioning of the cardiovascular and nervous systems. There is also a sedative effect and an effect that reduces anxiety, fear and restlessness.

The medicine contains vitamins that act as components of enzyme systems involved in oxidation-reduction processes in the body. For example, vitamin B, or pyridoxine hydrochloride, normalizes and supports the central and peripheral nervous system. Vitamin PP or nicotinamide is responsible for tissue respiration, carbohydrate and fat metabolism.

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Indications Sedavita.

Sedavit has the following indications for use:

• Regular psychological stress.
• Long-term emotional and physical stress.
• Neurasthenic reactions and neurasthenia.
• Increased irritability.
• A feeling of unfounded anxiety.
• Impaired memory and concentration.
• Emotional exhaustion.
• Increased weakness.
• Various itchy dermatoses, eczema, urticaria.

The medicine can be used in complex therapy of neurocirculatory dystonia of cardiac and hypertensive type. Sedavit is used in hypertsenic form of asthenic syndrome, arterial hypertension of stage I. It helps to cope with migraines and frequent headaches, insomnia, which are caused by increased psychological stress. In addition, the drug is effective in symptomatic therapy of climacteric syndrome and dysmenorrhea.

Release form

Sedavit is available in the following forms:

• Tablets for oral use - 10 capsules in a blister, 2 blisters in one package. One tablet contains: thick extract of medicinal plants 170 mg, pyridoxine hydrochloride 3 mg, nicotinamide 15 mg. The auxiliary component is lactose monohydrate.
• Oral solution – available in 100 and 200 ml glass bottles with a special dispenser. 100 ml of the medicine contains the following substances: liquid extracts of medicinal plants 94 ml, vitamin B6 – 60 mg, vitamin PP – 300 mg. The composition also includes an additional component – ethyl alcohol.

The form of the drug is determined by the attending physician, individually for each patient. As a rule, it depends on the patient's age and medical indications.

Pharmacodynamics

The sedative has a combined composition. Pharmacokinetics is based on the action of various plant extracts and vitamins. The drug has a wide pharmacological activity: pronounced neurotropic effect, improved sleep quality, antispasmodic, hypotensive and antiarrhythmic effect. The pharmacological action is based on the following components:

• Valerian extract - consists of biologically active substances, essential oils and organic acids. It has a sedative, choleretic, antispasmodic and vasodilatory effect. Valerian normalizes the sleep and wakefulness regime, improves night sleep, slightly slows the heart rate and increases the secretory activity of the mucous membranes of the gastrointestinal tract. The mechanism of action of this component is based on the ability to inhibit the central nervous system and increase the activity of cortical processes.
• Peppermint leaf extract – has a choleretic, antiseptic, sedative and analgesic effect. The substance prevents the development of hypoxia, stimulates the synthesis of endogenous biologically active substances by stimulating the cold receptors of the oral mucosa. This leads to a reflex expansion of the cerebral, coronary and pulmonary vessels.
• Hawthorn fruit extract – contains vitamins, essential oils, anthocyanins, organic acids. Has vasodilatory and sedative properties, reduces blood cholesterol levels and improves bile flow. Enhances blood circulation in the cerebral and coronary vessels. Reduces CNS and myocardial excitability.
• Hop cone extract contains vitamins, phytoestrogens and flavonoids. It has sedative, analgesic, antispasmodic and anti-inflammatory properties. Strengthens capillaries, increases tissue regeneration capacity. Improves the clinical picture in climacteric disorders, amenorrhea and estrogen deficiency.
• St. John's wort extract is a complex of biologically active components, vitamins and essential oils. Improves the functions of the central nervous system and peripheral nervous system, has an antidepressant and sedative effect. The drug exhibits bactericidal properties against a number of gram-positive microorganisms, including penicillin-resistant strains of staphylococcus.
• Nicotinamide – takes part in the process of tissue respiration and oxidation-reduction processes in cells. Regulates carbohydrate and fat metabolism.
• Pyridoxine hydrochloride – participates in the synthesis of enzymes and neurotransmitters of the central nervous system, normalizes protein and fat metabolism. Regulates tryptophan metabolism and hemoglobin synthesis, catabolic and anabolic metabolic processes.

The herbal and vitamin composition of Sedavit effectively reduces the feeling of increasing anxiety and nervous tension, improves concentration and memory.

Pharmacokinetics

After oral administration, the drug is quickly absorbed and distributed throughout the body's tissues. Metabolized in the liver, excreted by the kidneys. Pharmacokinetics is based on the combined action of all components of the drug. To achieve a pronounced therapeutic effect, Sedavit requires long-term use.

Dosing and administration

Since Sedavit has two forms of release and many indications, the method of administration and dosage should be determined by the attending physician.

• The tablets are taken orally, regardless of food intake. The capsule is swallowed whole with water. If there are bouts of nausea, it is better to take the medicine during meals. For adult and child patients, 2 tablets are prescribed 3 times a day. If necessary, a single dosage can be increased to 3 tablets. If the patient is inhibited during therapy, the dose should be reduced and an interval of 8 hours should be observed between doses. In case of increased emotional stress, the medicine is taken 2-3 tablets once 30-40 minutes before possible emotional stress.
• The solution is also intended for oral use. It can be taken undiluted or diluted with water, juice or tea. For adults and patients over 12 years old, 5 ml is prescribed 3 times a day, if necessary, the dosage can be increased to 10 ml. If side effects develop, the dose should be reduced to 2.5 ml. In case of emotional stress, the recommended dosage is 5-10 ml once 30 minutes before the expected experiences.

The duration of treatment depends on the results of the drug use during the first 1-2 weeks. As a rule, therapy with Sedavit is long-term, and complex use with other sedatives or tranquilizers is possible.

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Use Sedavita. during pregnancy

The use of sedatives during pregnancy is possible only on medical prescription, when the potential benefit to the mother is higher than the risks to the fetus. Use during pregnancy Sedavit, especially in the early stages, is not recommended. The drug is not recommended for use during breastfeeding. If there is a strong need for the drug, lactation must be interrupted.

Contraindications

Sedavit has the following contraindications for use:

• Hypersensitivity to the components of the drug.
• Erosive and ulcerative lesions of the gastrointestinal tract.
• Depressive disorders.
• Conditions with severe CNS depression.
• Ischemic heart disease.
• Myasthenia gravis.
• Bronchial asthma and tendency to bronchospasms.
• Liver diseases.
• Patients are under 12 years of age.

The drug is prescribed with special caution to patients with severe gastrointestinal diseases.

Side effects Sedavita.

As a rule, Sedavit is well tolerated. Side effects are extremely rare, but may manifest themselves as the following symptoms:

• Increased fatigue and drowsiness.
• Dizziness and headaches.
• Paresthesia.
• Emotional lability.
• Nausea, vomiting, bowel disturbances.
• Painful sensations in the epigastric region.
• Arterial hypotension.
• Decreased heart rate.
• Skin allergic reactions.
• Severe muscle weakness.

If side effects develop, you should stop taking the medication and consult your doctor.

Overdose

When using high doses of the drug, side effects develop. Overdose is most often manifested by the following symptoms:

• Drowsiness.
• Increased weakness.
• Feeling depressed.
• Attacks of nausea and vomiting.
• Myasthenia gravis.
• Pain in the epigastric region.
• Painful sensations in the joints.

It is also possible to develop symptoms of nicotinamide intoxication, i.e. tremors of the extremities, tachycardia, increased sweating, coughing, vomiting attacks, and a sharp decrease in blood pressure. There is no specific antidote, so symptomatic therapy, gastric lavage, and the use of enterosorbents are indicated.

Interactions with other drugs

Sedavit is prescribed for the complex treatment of various neurasthenic reactions. Interactions with other drugs are controlled by the attending physician. Thus, when used with ethanol and drugs that depress the central nervous system, an increase in their therapeutic effect is observed. Pyridoxine hydrochloride reduces the effectiveness of levodopa, so this interaction is not recommended.

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Storage conditions

It is recommended to keep the tablets and solution of the sedative herbal remedy in the original packaging, in a place protected from sunlight and moisture. Storage conditions imply maintaining a temperature regime not exceeding 15 °C. Failure to comply with storage rules may lead to premature deterioration of the medicine.

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Shelf life

Sedavit, regardless of its form of release, must be used within 24 months from the date of manufacture. The expiration date of the drug is indicated on its packaging and the bottle with the solution. Expired medication is prohibited for use for medicinal purposes. This is due to the risk of developing uncontrolled side effects.