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Sedavit
Sedative medicinal product based on plant components is Sedavit. Consider the pharmacological features of the drug and the rules for its use.
The complex composition of Sedavit provides an anxiolytic effect. This allows you to use it for severe nervous disorders and stresses. The composition of the medicine includes the roots of valerian, hawthorn fruit, St. John's wort, hop cones and peppermint leaves. Biologically active components have a positive effect on the functioning of the cardiovascular and nervous system. There is also a sedative and anxiety-reducing, fearful and anxious action.
The medication contains vitamins, which act as components of enzyme systems that take part in oxidation-reduction processes in the body. For example, vitamin B, that is, pyridoxine hydrochloride, normalizes and supports the work of the central and peripheral nervous system. Vitamin PP or nicotinamide, is responsible for tissue respiration, carbohydrate and fat metabolism.
Indications of the sedawita
Sedavit has such indications for use:
- Regular psychological stress.
- Long-term emotional and physical activity.
- Neurasthenic reactions and neurasthenia.
- Increased irritability.
- Feeling of causeless anxiety.
- Memory impairment and concentration of attention.
- Emotional exhaustion.
- Increased weakness.
- Various itching dermatoses, eczema, urticaria.
The medicine can be used in the complex therapy of neurocirculatory dystonia according to the cardiac and hypertensive type. Sedavit is used in the hypertensive form of asthenic syndrome, arterial hypertension, stage I. Helps cope with migraine and frequent headaches, insomnia, which are caused by increased psychological stress. In addition, the drug is effective in symptomatic therapy of menopausal syndrome and dysmenorrhea.
Release form
Sedavit has such forms of release:
- Tablets for oral administration - 10 capsules in a blister, in one package 2 blisters. The composition of one tablet includes: a thick extract of medicinal plants 170 mg, pyridoxine hydrochloride 3 mg, nicotinamide 15 mg. Lactose monohydrate acts as an auxiliary component.
- Solution for oral administration - available in 100 and 200 ml in bottles of glass with a special dispenser. 100 ml medicines contain such substances: liquid extracts of medicinal plants 94 ml, vitamin B6 - 60 mg, vitamin РР - 300 mg. Also in the composition is an additional component - ethyl alcohol.
The form of release of the drug is determined by the attending physician, individually for each patient. As a rule, this depends on the age of the patient and the medical indications.
Pharmacodynamics
The sedative has a combined composition. Pharmacokinetics is based on the action of various plant extracts and vitamins. The drug has a wide pharmacological activity: pronounced neurotropic action, improvement in sleep quality, antispasmodic, antihypertensive and antiarrhythmic effect. Pharmacological action is based on such components:
- Extract of valerian - consists of biologically active substances, essential oils and organic acids. Has sedative, choleretic, spasmolytic and vasodilating effect. Valerian normalizes sleep and wakefulness, improves night sleep, slightly slows heart rate and increases secretory activity of the mucous membranes of the gastrointestinal tract. The mechanism of action of this component is based on the ability to inhibit the central nervous system and increase the activity of cortical processes.
- Extract of peppermint leaves - has choleretic, antiseptic, sedative and analgesic effect. The substance prevents the development of hypoxia, stimulates the synthesis of endogenous biologically active substances by stimulating the cold receptors of the oral mucosa. This leads to a reflex expansion of the cerebral and coronary vessels and vessels of the lungs.
- Hawthorn fruit extract - contains vitamins, essential oils, anthocyanins, organic acids. Has vasodilator and sedative properties, lowers cholesterol in the blood and improves the outflow of bile. Increases blood circulation in the cerebral and coronary vessels. Reduces the excitability of the central nervous system and myocardium.
- Hops cone extract is vitamins, phytoestrogens and flavonoids. Has sedative, analgesic, antispasmodic and anti-inflammatory properties. Strengthens capillaries, increases the ability of tissues to regenerate. Improves the clinical picture with menopausal disorders, amenorrhea and estrogen deficiency.
- Herb extract is a complex of biologically active components, vitamins and essential oils. It improves the functions of the central nervous system and the peripheral nervous system, has an antidepressant and sedative effect. The drug shows bactericidal properties against a number of gram-positive microorganisms, including penicillin resistant strains of staphylococcus.
- Nicotinamide - takes part in the process of tissue respiration and oxidation-reduction processes in cells. Regulates carbohydrate and fat metabolism.
- Pyridoxine hydrochloride - is involved in the synthesis of enzymes and neurotransmitters of the central nervous system, normalizes protein and fat metabolism. Regulates metabolism of tryptophan and hemoglobin synthesis, catabolic and anabolic metabolic processes.
Vegetative-vitamin composition Sedavit effectively reduces the feeling of growing anxiety and nervous tension, improves concentration and memory.
Pharmacokinetics
After ingestion, the drug is quickly absorbed and distributed to the tissues of the body. Metabolizes in the liver, excreted by the kidneys. Pharmacokinetics is based on the combined action of all components of the drug. To achieve a pronounced therapeutic effect, Sedavit requires a long-term use.
Use of the sedawita during pregnancy
The use of sedatives during the period of gestation is possible only for medical purposes, when the potential benefit to the mother is higher than the risks to the fetus. Use during pregnancy Sedavit, especially in the early stages, is not recommended. It is not recommended to take this medication during breastfeeding. If there is a pronounced need for the drug, it is necessary to interrupt lactation.
Contraindications
Sedavit has such contraindications for use:
- Hypersensitivity to the components of the drug.
- Erosive-ulcerative lesions of the digestive tract.
- Depressive disorders.
- Conditions with severe CNS depression.
- Cardiac ischemia.
- Myasthenia gravis.
- Bronchial asthma and a tendency to bronchospasm.
- Diseases of the liver.
- The age of the patients is less than 12 years.
With special care, the drug is prescribed for patients with severe diseases of the gastrointestinal tract.
Side effects of the sedawita
As a rule, Sedavit is well tolerated. Side-effects are extremely rare, but can manifest themselves with such symptoms:
- Increased fatigue and drowsiness.
- Dizziness and headaches.
- Paresthesia.
- Emotional lability.
- Nausea, vomiting, stool disorders.
- Painful sensations in the epigastric region.
- Arterial hypotension.
- Reduction of heart rate.
- Skin allergic reactions.
- Severe muscle weakness.
With the development of side effects, you must stop taking the medicine and consult your doctor.
Dosing and administration
Since Sedavit has two forms of release and a variety of indications, the method of administration and dose should be determined by the attending physician.
- Tablets are taken orally, regardless of food intake. Capsule swallowed whole, washed down with water. If there are bouts of nausea, then the medicine is better to eat while eating. For patients of adult age and children appoint 2 tablets 3 times a day. If necessary, a single dosage can be increased to 3 tablets. If during the therapy the patient is in a hindered state, the dose should be reduced and the interval between doses taken within 8 hours should be observed. With increased emotional stress, the medication is taken 2-3 tablets once for 30-40 minutes before possible emotional stress.
- The solution is also intended for oral administration. It can be used both undiluted and diluted with water, juice or tea. For adults and patients older than 12 years, appoint 5 ml 3 times a day, if necessary, the dosage can be increased to 10 ml. With the development of adverse reactions, the dose should be reduced to 2.5 ml. At emotional loads, the recommended dosage is 5-10 ml once for 30 minutes before the expected experiences.
The duration of treatment depends on the results of the application of the remedy within the first 1-2 weeks. As a rule, therapy with Sedavit is prolonged, possibly integrated with other sedatives or sedatives.
Overdose
At application of the raised doses of a preparation, development of collateral symptoms is observed. Overdose is most often manifested by such signs:
- Drowsiness.
- Increased weakness.
- Feelings of depression.
- Attacks of nausea and vomiting.
- Myasthenia gravis.
- Pain in the epigastric region.
- Painful sensations in the joints.
It is also possible to develop symptoms of intoxication with nicotinamide, that is tremor of the extremities, tachycardia, increased sweating, coughing, attacks of vomiting, a sharp drop in blood pressure. There is no specific antidote, therefore symptomatic therapy, gastric lavage and enterosorbents are indicated.
Interactions with other drugs
Sedavit is prescribed for the complex treatment of various neurasthenic reactions. Interactions with other drugs are controlled by the attending physician. So, when used with ethanol and drugs that depress the central nervous system, there is an increase in their therapeutic effect. Pyridoxine hydrochloride lowers the effectiveness of levodopa, so this interaction is not recommended.
Storage conditions
Tablets and a solution of sedative plant remedies, it is recommended to keep in their original packaging, in a place protected from sunlight and moisture. Storage conditions imply compliance with the temperature regime not exceeding 15 ° C. Failure to comply with the storage regulations can lead to premature deterioration of the drug.
Shelf life
Sedavit, regardless of its form of release, must be used within 24 months from the date of manufacture. The expiration date of the medicine is indicated on its packaging and the vial with the solution. An overdue product is not allowed for medical purposes. This is associated with the risk of developing uncontrolled adverse reactions.