Cedalgin-neo

Sedalgin-neo is an anti-inflammatory and analgesic drug from the pharmacotherapeutic group of NSAIDs. Let's consider the indications for its use, dosage.

Non-steroidal anti-inflammatory drug with a sedative effect and complex composition. Paracetamol and metamizole sodium inhibit COX and disrupt the production of prostaglandins. Phenobarbital provides sedation, potentiating analgesic components. Due to caffeine, cerebral vasodilation and a decrease in painful sensations are observed.

Indications Cedalgin-neo

The combined composition of the drug provides a wide range of its use. Let's consider the indications for the use of Sedalgin-neo:

• Acute ENT infections.
• Phantom pains.
• Dental pain.
• Myalgic pain.
• Unspecified neuritis.
• Dysmenorrhea of unknown origin.
• Painful sensations of a chronic nature.
• Migraines and headaches.
• Sciatica.
• Rheumatic pain.
• Pain of a traumatic nature.
• Postoperative and post-burn pain.

The medicine is available without a prescription, but to avoid side effects, it is worth consulting a doctor.

Release form

Sedalgin-neo is available in tablet form. One tablet contains the following substances:

• Paracetamol 300 mg
• Metamizole sodium 150 mg
• Caffeine 50 mg
• Codeine phosphate 10 mg
• Phenobarbital 1.5 mg

The auxiliary components are: talc, magnesium stearate, povidone, crospovidone, sodium metabisulfite. The medicine is available in packages of 10 and 20 tablets.

Pharmacodynamics

The drug has a combined composition that provides analgesic, anti-migraine and antipyretic action. Pharmacodynamics is represented by the following substances:

• Caffeine - stimulates the psychomotor centers of the brain. This leads to increased performance, physical and mental activity, decreased fatigue and drowsiness,
• Codeine - suppresses the excitability of the cough center and produces an analgesic effect, which is caused by the excitation of opiate receptors of the central nervous system. Depresses breathing, promotes relaxation of smooth muscles of the intestine, reduces peristalsis and spasms of all sphincters.
• Metamizole is a non-steroidal anti-inflammatory drug with antipyretic, antispasmodic and analgesic properties.
• Paracetamol is a non-narcotic analgesic with antipyretic properties. It blocks COX1 and COX2 in the central nervous system, affects the thermoregulation and pain centers.
• Phenobarbital is an antiepileptic substance that has sedative, hypnotic, antispasmodic and muscle relaxant properties.

All active components of the drug interact with each other, providing a therapeutic effect.

Pharmacokinetics

After oral administration, the active substances are quickly absorbed and absorbed, spreading throughout the body. Pharmacokinetics indicates that the therapeutic effect develops 30-40 minutes after taking the tablets, and lasts for 4-6 hours. The drug is excreted by the kidneys with urine, in the form of metabolites.

Dosing and administration

Sedalgin-neo is recommended for use as prescribed by a doctor. The method of administration and dosage of the drug depend on the indications for its use and the severity of painful symptoms. Tablets should be taken 1 pc. 2-4 times a day, the maximum daily dose should not exceed 6 tablets.

The duration of therapy is determined by the attending physician. But if the drug is used for more than 1 week, it is necessary to monitor the functional state of the liver and the state of the peripheral blood. During treatment, it is contraindicated to drink alcohol and engage in potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

Use Cedalgin-neo during pregnancy

Sedalgin-Neo is not recommended for use during pregnancy. This is due to the fact that the active components of the drug can be dangerous for the fetus. There is a risk of developing pathological abnormalities in the child's development and a number of other problems.

Contraindications

The main contraindications to the use of Sedalgin-Neo are related to individual intolerance to its components. Also, the drug is not recommended for use in such cases:

• Pregnancy and lactation.
• Anemia.
• Gastric ulcer in the acute phase.
• Hemorrhagic diathesis.
• Bronchial asthma.
• Kidney and liver pathologies.
• Peptic ulcer of the duodenum.
• Treatment of patients under 14 years of age.

If the above contraindications are present, the doctor selects a safer medication.

Side effects Cedalgin-neo

The use of Sedalgin-Neo tablets may cause the following side effects:

• Various allergic reactions.
• Nausea, vomiting, epigastric pain.
• Stool disorders (diarrhea, constipation).
• Hemolytic anemia.
• Increased irritability and sleep disturbances.
• Thrombocytopenia and hypotension.
• Headaches and dizziness.
• Dryness of the oral mucosa.
• Impaired liver function.
• Increased heart rate.
• Increased anxiety.
• Tremor of the limbs.
• Asthmatic attacks.
• Impaired coordination of movements.

With prolonged use of the drug, addiction may develop.

Overdose

The use of increased doses of Sedalgin-Neo may cause overdose symptoms. Most often, this is manifested by an asthenic state, headaches and dizziness, inhibition of reflex reactions, increased dryness of the oral mucosa. In case of a severe overdose, loss of consciousness and depression of the respiratory center are possible.

To eliminate an overdose, measures to cleanse the gastrointestinal tract and further symptomatic therapy are indicated.

Interactions with other drugs

Sedalgin-Neo can be used in combination therapy. All possible interactions with other drugs are controlled by the attending physician. Let's consider the main interactions of the drug with other medications and their possible results:

• Hypnotics – may increase central nervous system depression.
• NSAIDs – increased risk of gastrointestinal bleeding, hemolytic reactions.
• Oral coagulants - various uncontrolled adverse reactions.
• Sedatives – enhancement of the analgesic effect of Sedalgin-neo, CNS depression.
• Antipsychotic drugs and narcotic analgesics – increase the sedative effect.
• Anxiolytics – enhancement of analgesic effect, CNS depression.

If Sedalgin-Neo is prescribed simultaneously with Cyclosporine, a decrease in the activity of the latter is observed. When interacting with Rifampicin and contraceptives, the analgesic effect decreases. Cytostatics increase hematotoxicity.

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Storage conditions

According to storage conditions, tablets must be kept in the original packaging, protected from sunlight, moisture and out of reach of children. The recommended storage temperature should be within 15-25 ºС.

Shelf life

Sedalgin-Neo must be used within its expiration date. It is 36 months from the production date, which is indicated on the drug packaging. After its expiration, the medicine must be disposed of and is prohibited for use.