Sedasen

Sedasen is a combined sedative. Let's consider the indications for its use, dosage, possible side effects and other nuances of use.

The medicine belongs to the pharmacological group of sleeping pills and sedatives on a plant basis. The combined composition provides a synergistic effect. The drug can be purchased without a prescription, but before using it, you should consult a doctor.

Indications Sedasena

Sedasen is used to treat mild neurological disorders. Let's look at the main indications for its use:

• Neurasthenia and neurosis.
• Nervous tension.
• Increased irritability.
• Anxiety, fear, depression.
• Increased fatigue.
• Sleep disorders.

In addition to the above indications, the medicine can be used in complex therapy of headaches and migraines, which are associated with nervous tension. It helps with mild forms of dysmenorrhea, climacteric syndrome, neurocirculatory dystonia with tachycardia, cardialgia or hypertensive syndrome, as well as with prolonged mental stress and insufficient concentration.

Release form

Sedasen is available in tablet form. The medicine is available in the form of hard gelatin capsules for oral use. One capsule contains the following substances: 50 mg dry valerian extract, 25 mg dry peppermint extract, 25 mg lemon mint. Excipients: lactose, colloidal silicon dioxide, talc, gelatin, iron oxide, titanium dioxide.

Sedasen forte. A combined herbal remedy with sedative properties. Reduces the level of irritability and excitability of the central and autonomic nervous system, helps with mental fatigue. Valerian has a hypnotic and antispasmodic effect. This substance activates the secretory functions of the mucous membranes of the gastrointestinal tract, has a choleretic effect, dilates the coronary vessels and slows the heart rate. Essential oil of peppermint leaves stimulates the secretory activity of the digestive glands, reduces dyspeptic disorders, nausea.

• Indications for use: mild forms of neurosis and neurasthenia, anxiety, irritability, increased excitability and fatigue. Migraine and headaches, arterial hypertension, decreased concentration, dermatoses.
• Method of administration and dosage: the drug is prescribed to patients over 12 years old, 1 capsule 2-3 times a day. The maximum daily dosage is 6 capsules. Duration of treatment is from 2 weeks to 3 months. In some cases, therapy can last up to 1 year.
• Side effects: lethargy, drowsiness, dizziness, allergic skin reactions.
• Contraindications: patients under 12 years of age, individual intolerance to the components of the drug, pregnancy and lactation.
• Overdose: dyspeptic disorders, arterial hypotension, depression, drowsiness, dizziness. Gastric lavage and further symptomatic therapy are indicated for treatment.

Sedasen Forte is contraindicated to be taken simultaneously with alcohol, antispasmodic drugs, antihypertensives and other sedatives.

Pharmacodynamics

The drug contains several active components of plant origin. The pharmacodynamics of Sedasen is based on their mechanism of action:

• Valerian - contains esters of borneol and isovaleric acid, valeropotriates, alkaloids valerine and hotenine. These substances reduce the excitability of the central nervous system, have a sedative, choleretic, antispasmodic effect. Biologically active substances slow the heart rate and dilate the coronary vessels.
• Peppermint – has a wide range of pharmacological activity. It has antispasmodic, hypnotic and sedative effects. Reduces nausea, stimulates the secretion of digestive glands.
• Melissa (lemon mint) – has anticonvulsant, sedative, hypotensive, antispasmodic and antiemetic properties. Improves digestion, has a mild choleretic effect, normalizes appetite.

The active ingredients are not addictive.

[ 1 ], [ 2 ], [ 3 ], [ 4 ], [ 5 ], [ 6 ], [ 7 ]

Pharmacokinetics

After oral administration, the drug is rapidly absorbed and distributed throughout the body. Pharmacokinetics indicate low binding to plasma proteins. The therapeutic effect occurs within 20-30 minutes and lasts for 4-5 hours. The drug is excreted by the kidneys as metabolites in the urine.

[ 8 ], [ 9 ], [ 10 ], [ 11 ], [ 12 ], [ 13 ]

Dosing and administration

Sedasen is prescribed for the treatment of patients over 12 years of age. The method of administration and dosage depend on the severity of the disease and the doctor's recommendations.

• For children and adolescents with increased mental stress, 1-2 capsules 2-3 times a day are prescribed.
• For insomnia – 1-2 capsules 1 hour before bedtime.
• For increased nervous excitement and irritability – 1-2 capsules 2-3 times a day.

The maximum daily dosage should not exceed 6 tablets, divided into 3 doses. To achieve a stable therapeutic effect, the course of treatment should be at least 14 days. With prolonged use, the drug does not cause addiction.

[ 14 ]

Use Sedasena during pregnancy

The effectiveness and safety of Sedasen during pregnancy have not been established. The drug is used when the potential benefit to the mother is higher than the possible risks to the fetus. The drug is not recommended during lactation and may affect the speed of psychomotor reactions.

Contraindications

Sedasen has the following contraindications for use:

• Hypersensitivity to the components of the drug.
• Severe arterial hypotension.
• Bronchial asthma.
• Depression.
• A condition with severe depression of the respiratory and central nervous systems.

The drug is not used to treat patients under 12 years of age.

Side effects Sedasena

In some cases, Sedasen may cause the following side effects:

• Nausea and vomiting.
• Spasmodic pain in the abdomen.
• Heartburn.
• Increased drowsiness and weakness.
• Frequent mood swings.
• Decreased concentration and performance.
• Skin allergic reactions.

If the above symptoms occur, you should stop taking the drug and seek medical attention.

Overdose

The use of high doses of Sedasen may cause the following overdose symptoms:

• Fatigue.
• Muscle spasms.
• A feeling of tightness in the chest.
• Dizziness and headaches.
• Tremor of the limbs.
• Dilation of the pupils.
• Decreased hearing and vision acuity.
• Bradycardia.

Side effects disappear on their own within 24 hours. Symptomatic therapy is administered if necessary.

Interactions with other drugs

Sedasen has limited interactions with other drugs. The drug enhances the sedative, antispasmodic, analgesic and hypnotic properties of other drugs. Clinically significant interactions with substances metabolized by cytochrome CYP2D6, CYP3A4 / 5, CYP1A2 or CYP2E1 have not been established. Concomitant use with synthetic sedatives is not recommended.

[ 15 ]

Storage conditions

According to storage conditions, Sedasen must be kept in a place protected from sunlight and inaccessible to children. The temperature in the storage place should not exceed 25 ºС. If these conditions are not met, the drug may prematurely lose its pharmaceutical properties.

[ 16 ]

Shelf life

Sedasen must be used within 24 months from the date of manufacture. The expiration date is indicated on the packaging of the drug. After its expiration, the medicine must be disposed of. Taking expired tablets is contraindicated.