Sanorin

Sanorin is a decongestant used to treat diseases developing in the nasal cavity. Included in the category of sympathomimetics.

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Indications Sanorin

It is indicated for use in the acute form of the common cold. It can also be used as an auxiliary medicine in the treatment of inflammation in the paranasal sinuses, as well as otitis. Helps reduce mucosal edema during diagnostic procedures.

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Release form

Produced in the form of drops in bottles of 10 ml (in the kit is also a special lid-dropper). One package contains 1 bottle.

Pharmacodynamics

Nafazoline is a substance that stimulates the function of sympathetic HC, and also affects α-adrenergic receptors. Vasoconstrictive properties can reduce puffiness, exudation and flushing, thereby facilitating breathing through the nose in colds.

Thanks to the active component of the medicine, the outflowing ducts of the paranasal sinuses and the Eustachian tubes are opened and expanded, which improves secretion and prevents the bacteria from settling.

Pharmacokinetics

With local use of the substance, it is completely absorbed. The drug effect after intranasal administration occurs after about 5 minutes and lasts about 4-6 hours.

Dosing and administration

For children 3-6 years, the dosage is 1-2 drops in each of the nostrils, at the age of 6-15 years - 2 drops, for children from 15 years and adults - 1-3 drops. The medicine should be administered three times a day, with an interval between the procedures of at least 4 hours. If the process of breathing through the nose is noted, treatment can be completed. Reuse of drops is allowed only after a few days.

When diagnosing the nasal cavity with endoscopy (for example, when diagnosing, as well as treating polyps in the nose), 3-4 drops should be instilled in each of the nostrils after the procedure for cleansing the nose. Or place a cotton swab in the nostril, treated with a solution of the drug, and hold it for about 2-3 minutes.

If bleeding from the nose should also be inserted into the nostril swab of cotton wool, treated Sanorin.

With edema of the vocal cords, a laryngeal syringe is used, which is injected into the throat with 1-2 ml of the drug.

The medicine should be instilled in turn into each of the nostrils, while slightly deflecting the head back. Also, at the time of instilling the left hole, it is recommended that the head be tilted slightly to the left side, and at the time of instillation of the right one, respectively, to the right side.

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Use Sanorin during pregnancy

There is no information on the passage of naphazoline through the placental barrier or into breast milk, so before using the medication it is necessary to evaluate the benefits of its effect on the mother, as well as the possible negative consequences for the fetus.

Contraindications

Among the contraindications:

• individual intolerance of medicinal components;
• chronic or atrophic form of the common cold;
• glaucoma of the closed type;
• eye pathologies in severe form;
• elevated blood pressure;
• severe form of atherosclerosis;
• the presence of hyperthyroidism, tachycardia, or diabetes mellitus;
• combination with MAO inhibitors, and also for a period of at least 2 weeks after completion of their use;
• 0.05% solution of the drug is banned for children under 2 years, and 0.1% for children under 15 years of age.

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Side effects Sanorin

Patients with an individual intolerance to the components of the medicine can feel a burning sensation in the nose, as well as dryness of the nasal mucosa. Single in patients there is a feeling of severe stuffiness in the nose.

Occasionally, systemic adverse reactions may develop (mainly due to an overdose):

• organs of the immune system: allergy (burning, angioedema);
• organs of the National Assembly: headaches, development of nervousness or tremor;
• organs of the cardiovascular system: rapid heart rate or tachycardia;
• cardiovascular system: increased blood pressure;
• skin and subcutaneous tissues: increased sweating.

Long (longer than 5 days for adults or more than 3 days for children) or frequent use of drugs can be addictive, against which there is a strong swelling of the nasal mucosa (appears soon after the administration of drops).

Continuous intranasal administration of the drug can cause damage to the epithelium of the mucosa, and in addition to this, inhibition of the activity of epithelial cilia. As a result, damage to the mucosa will become irreversible, and the patient will develop a dry rhinitis.

Overdose

Due to accidental oral administration of drugs or overdose, such systemic side reactions are possible: increased sweating, a feeling of nervousness, and in addition headaches, heart rhythm disorders, tremors, as well as increased blood pressure and tachycardia. In addition, nausea, fever, cyanosis, pulmonary edema, cardiac arrest, spasms, respiratory distress, heart attack and blanching of the skin can be observed.

Suppression of the function of the central nervous system manifests itself in the form of such symptoms: a decrease in temperature, increased sweating, a bradycardia, a shock state (similar to hypotensive), apnea, drowsiness, and also coma. The likelihood of an overdose in children is higher, as they are more prone to negative effects of drugs.

Symptomatic therapy is required to eliminate these symptoms.

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Interactions with other drugs

The combination of Sanorin with MAO inhibitors, and in addition tricyclics and maprotiline (or for several days after completion of their admission) may increase the level of blood pressure.

[6], [7], [8], [9]

Storage conditions

The drug should be maintained in standard conditions for medicines, and also in the temperature regime of no more than 25 ° C.

Shelf life

Sanorin is allowed to be used for 4 years. But after opening the package - only for 1 year.