Sanguirithrin

Antimicrobial agent Sangviritrin is a plant antiseptic that produces from the herbaceous plant a two-species makleyi - heart-shaped and small-fruited, belonging to the family of poppies. Antimicrobial drug is a biosulfate complex related in structure and characteristics of alkaloid substances, chelerythrin and sanguinarine.

Indications Sanguirithrin

The antimicrobial drug Sanguirythrine can be used for therapeutic or prophylactic measures, in pediatrics or in adult patients, starting from the period of the newborn. Sanguirythrin can be used as needed during pregnancy and after childbirth.

For prophylactic purposes, sanguirithrin is used in newborn babies to prevent infectious lesions of the skin, as well as in patients with surgical pathology to prevent purulent and inflammatory processes in wounds.

With a curative purpose, Sanguirithrin is prescribed for infectious and inflammatory processes in skin and mucous tissues, both of microbial and fungal origin.

The drug can be used as an auxiliary in dental practice for periodontal inflammation, with gingivitis and stomatitis, as well as other inflammatory processes of the oral mucosa.

Surgeons use Sangviritrin for the treatment of infected wound processes, burns, slow wounds and ulcers.

Otolaryngologists use the drug to treat the pathology of the middle ear, or inflammation of the auricle and the outer part of the ear canal.

Gynecologists can use Sanguirithrin to treat patients with erosion, vaginitis, colpitis, endocervicitis.

In dermatological practice, Sanguirithrin is used for purulent skin lesions, mycosis.

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Release form

Sanguirythrine is an alcoholic liquid of 0.2%, which is used exclusively for outdoor procedures. The liquid has a rich orange hue and a characteristic alcoholic odor.

The antiseptic agent consists of the active ingredient of sanguirithrin and additional substances - ethyl alcohol and water.

The drug Sangviritrin is poured into dark glass bottles, which are then placed in cardboard boxes. The kit includes an abstract to the antimicrobial agent.

The names of the analogues of Sangviritrin

Equivalent analogues of the antimicrobial Sangviritrin do not exist, but there are a number of agents with a similar mechanism of action. We suggest that you familiarize yourself with the list of drugs similar in effect.

• Antisept - 70% outdoor solution.
• Antiseptol - 70% of the external solution.
• Ascocept is an external preparation.
• AHD 2000 is an external antimicrobial agent.
• Biosept 70 - solution.
• Vitasept 70% and 96% liquid.
• Vitafarm 70% and 96% of the external agent.
• Euraetil 70% and 96% of the external agent.
• Megassept and Medasept - alcohol solutions.
• Septly - alcohol liquids 70% and 96%.
• Septosteryl is an antiseptic for external use.
• Pharmasept - a solution of 96%.

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Pharmacodynamics

Antiseptic Sangviritrin acts on a large number of pathogenic microbes, including gram (+) and gram (-) bacteria, yeast and mycelium. The drug shows activity against microbial strains that are resistant to most antibiotics.

Standard dosages of Sanguirithrin have a bacteriostatic effect - stop the growth and multiplication of the infection.

The essence of the antibacterial effect of the drug consists in the inhibition of microbial nuclease, the breakdown of mechanisms that ensure cell permeability, metabolic processes inside cells and violating the nucleotide structure.

Pharmacokinetics

There is no evidence of the ingestion of the external antiseptic Sangviritrin in the systemic bloodstream, so the kinetic properties of the drug can not be described.

Dosing and administration

Antiseptic Sanguirithrin is used only as an external agent.

On the fifth or sixth day after the birth of the child, the preparation processes the folds of the skin, in the morning and in the evening.

When the periodontal inflammation is in the pockets of the pockets, place the cotton flagellum with the drug Sangviritrin, holding them for about 20 minutes. To prepare a less concentrated aqueous solution of Sangviritrin, 1 tsp is mixed. 0.2% alcohol and 200 ml of pure boiled water. The introduction of cotton flagella is carried out every day or once every two days. The general course of treatment involves 5-6 procedures.

For the treatment of stomatitis, the application application of Sanguirithrin is prescribed up to three times a day for 3-5 days. Older children can be recommended rinsing the mouth with a diluted solution. To small children till 5-year-old age put divorced preparation directly on mucous.

For treatment of catarrhal diseases, the tonsils are treated with 0.2% liquid overnight, for 3-4 days. Older children and adults can gargle with a heated diluted solution. Duration of treatment - up to 1 week.

When the ear becomes inflamed, a cotton flagellum impregnated with 0.2% Sanguirithrin is added to the auditory courses and left for 15 minutes. The procedure is repeated up to 3 times a day. The duration of therapy is at least 14 days. If the inflammatory process has a chronic course, then Sangviritrin drips into the auditory meatus for 5-7 drops for an adult patient, and up to 2 drops for children.

As a prophylaxis of wound complications, the wound is treated with a gauze cloth impregnated with 0.2% Sanguirithrin. You can leave a lotion with an antiseptic under the bandage. The duration of treatment is determined by the doctor, depending on the course of wound surface healing. Most often, it may take one week to partially tighten the wound.

In the presence of infection in the wound, with sluggish, hard-healing processes, dilute Sanguirithrin is used to rinse and apply lotions.

With gynecological diseases, the diluted solution is used for douching, appliqués and baths. Procedures are carried out every day, for 5 days, 1-2 times (for example, in the morning and in the evening).

In purulent skin diseases or dermatomycosis 0.2% Sanguirythrin is used in the form of bandages or applied to the affected areas, up to 2 times a day. The duration of treatment is determined by the doctor.

Use Sanguirithrin during pregnancy

Antimicrobial agent Sangviritrin is allowed for external use in women during pregnancy. Treatment should be prescribed by a doctor and under his supervision.

The use of the drug in the period of breastfeeding is also not prohibited, if there is a corresponding indication.

Contraindications

The antimicrobial agent Sangviritrinum can not be prescribed:

• patients with epilepsy;
• at hyperkinesias;
• with bronchial asthma;
• with severe angina pectoris;
• with acute hepatic and renal insufficiency;
• with fungal skin lesions, which are accompanied by signs of eczematism;
• with a high probability of developing an allergic reaction to the drug.

Side effects Sanguirithrin

External application of Sanguirithrin on the skin can be accompanied by reddening and a transient burning sensation. It is also possible to develop an allergic reaction to the drug.

When using the antimicrobial agent Sangviritrin on the oral mucosa may appear a short bitter taste in the mouth.

If the patient has noticed similar side effects, then it is recommended to use a solution of lower concentration.

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Overdose

With frequent or abundant use of the external drug Sangviritrin sometimes there is an increased manifestation of side effects. If this happens, the concentration of the antimicrobial agent should be reduced. If necessary, perform symptomatic treatment.

Interactions with other drugs

Sangviritrin can be used in combination with various external medicines - in particular, with preparations of local anesthetic action (for example, with Promecaine or Trimekaine).

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Storage conditions

Antiseptic Sanguirythrin is stored in dark places, away from children's access, adhering to a temperature regime of +15 to +25 ° C.

Shelf life

Shelf life of the drug - up to 3 years, subject to proper storage conditions.

Do not use Sanguirythrine if its shelf life has come to an end, as by this time the drug loses its pharmacological activity.