Rectal anti-inflammatory suppositories

, medical expert
Last reviewed: 11.04.2020

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Suppositories are considered a very popular form of medications, because with their help you can quickly get a positive therapeutic result. They do not have such a large list of contraindications, like tablets or injectable solutions. Most often, rectal anti-inflammatory suppositories are used to treat various diseases of the reproductive system and intestines. They are no less effective in the treatment of diseases of the genitourinary system.

Candles, or as they are called suppositories, have the shape of a cone. At room temperature they are able to maintain their shape, but after the temperature rises, they immediately begin to melt. Due to this, a sufficient amount of active substance enters the patient's body.

What are the advantages of suppositories?

  1. Rapid action - after 30 minutes after getting the rectal suppository inside, 50% of the active component of the drug is found inside the patient's blood, and in an hour this amount increases to 100%. In this case, the active substances pass the liver and fall immediately into the rectum.
  2. They do not create uncomfortable feelings for the patient.

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Indications of the rectal anti-inflammatory suppositories

The most popular in medicine is the anti-inflammatory suppository with wound healing and thrombotic action. They are used to treat a wide variety of diseases:

  1. Cracks in the rectum.
  2. Hemorrhoids.
  3. Colpitis.
  4. Inflammatory processes in the intestine, including Crohn's disease, ulcerative colitis.
  5. Endometritis.
  6. Adnexitis.
  7. Inflammation of other organs of the reproductive system.

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Release form

Today in pharmacies you can find a huge number of a wide variety of rectal suppositories with anti-inflammatory effect. They are all used to treat various diseases and are based on the action of various active components. It is worthwhile to understand that for effective treatment it is necessary to strictly adhere to the advice given to you by the doctor in charge of the drug. Among the most popular rectal suppositories with anti-inflammatory effect is:

  1. Voltaren.
  2. Diclofenac.
  3. Flamax.
  4. Movalis.
  5. Hexicon.
  6. Polizhinaks.
  7. Meratin-Combi.
  8. Mikozhinax.
  9. Proctosan.
  10. Neo-Anusol.
  11. Anusole.
  12. Procto-Glivenol.

The use of rectal anti-inflammatory suppositories in gynecology

Rectal suppositories with anti-inflammatory action are generally used to treat a variety of inflammatory processes in the reproductive system, including andexitis and endometritis. Additionally, such suppositories are characterized by an analgesic and antipyretic effect. It should be remembered that in gynecology the rectal suppository with anti-inflammatory action is usually only a supplement to the main therapeutic course. Thanks to suppositories, the effect of other antibacterial drugs is enhanced and recovery comes faster.

In the treatment of various diseases of the female reproductive system, such candles are most often used: Voltaren, Diclofenac, Flamax, Movalis.

Voltaren. Drug based on the active component of diclofenac sodium. This substance is included in the group of non-steroidal anti-inflammatory drugs that have analgesic, anti-inflammatory, antipyretic effect.

Dosage of the drug is prescribed by the attending physician, with, as a rule, a minimally effective dose is used to avoid the development of side effects. Suppositories are injected directly into the rectum. Use the product recommended after emptying. The standard initial dose is up to 150 mg of the drug in 24 hours. It can be divided into two or three applications.

Voltaren is not recommended for proctitis, stomach ulcer, hives, bronchial asthma, rhinitis in acute form. It is also forbidden to use it for the treatment of children under 18 years of age. It can be the cause of thrombocytopenia, anaphylactic reaction, diplopia, depression, headaches, myocardial infarction, vasculitis.

Diclofenac. Drug based on the active ingredient diclofenac sodium. It differs by moderate antipyretic, analgesic and anti-inflammatory action.

The following dosage is used for treatment: up to 50 mg of the drug is applied no more than three times in 24 hours. It is not recommended to use Diclofenac in the aspirin triad, stomach ulcer, hematopoiesis. Use with caution to treat pregnant women.

Admission Diclofenac can cause diarrhea, vomiting, abnormalities in the liver, anemia, hair loss, paresthesia, swelling, allergies, photosensitivity, headaches.

Flamax. Drug based on the active component of ketoprofen. Nonsteroidal anti-inflammatory drug, which also differs antipyretic and analgesic action. Inflammation is removed, as a rule, one week after the start of therapy.

The dosage is determined by the attending physician depending on the patient's condition and the severity of the disease. The standard dose is as follows: 100-200 mg of the drug must be divided into several doses in one day. This remedy can be combined with other drugs to achieve an effective result.

Flamax is not recommended for the treatment of patients with rhinitis, bronchial asthma, gastric ulcer, Crohn's disease, diverticulitis, hemophilia, peptic ulcer, kidney disease, hyperkalemia. Also, do not take the drug to pregnant women and children under 6 years. It can cause allergies, dyspepsia, stomatitis, headaches, insomnia, vertigo, conjunctivitis, myalgia, exfoliative dermatitis.

Movalis. Drug based on the active ingredient meloxicam. This substance is an enolic acid derivative, therefore it is characterized by antipyretic, anti-inflammatory and analgesic effect.

Suppositories Movalis are used, as a rule, for 7.5 mg of the drug once every 24 hours. If the patient's condition is more severe, the dosage may be increased to 15 mg. To avoid the development of side effects from the use of suppositories, it is recommended to take a minimally effective dose.

Do not use the drug in case of stomach ulcers, Crohn's disease, acute and chronic liver diseases, bronchial asthma, stomach bleeding, hyperkalemia, pregnancy. Taking Mawalis can cause nausea, gastritis, colitis, hepatitis, leukopenia, thrombocytopenia, bronchospasm, photosensitization, headaches, kidney problems.

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Anti-inflammatory rectal suppository for intestines

To treat intestinal diseases, in particular, colitis, rectal suppositories with antibacterial effect are often used. Thanks to them, you can quickly destroy the pathogens that caused the disease. The most popular suppositories with anti-inflammatory effect for the treatment of inflammatory bowel diseases are: Geksicon, Polizhinaks, Meratin-Kombi, Mikozhinaks.

Hexicon. The drug is based on the active ingredient chlorhexidine bigluconate. It has antibacterial action against gram-positive and gram-negative microorganisms (Neisseria gonorrhoeae, Treponema pallidum, Gardnerella vaginalis, Chlamydia spp., Ureaplasma spp).

The dosage of the hexicon depends on the patient's condition, therefore it is established exclusively by the attending physician. In addition, the dose and duration of therapy also depend on the disease itself.

Doctors do not recommend using the remedy for dermatitis and allergies, also it is necessary to use with caution the hexicon for the treatment of children. Taking this medication can cause itching, allergies, dermatitis, photosensitivity, a taste disorder.

Polizhinaks. The drug is based on the active components of polymyxin B sulfate, neomycin sulfate, nystanine. It is an effective antibacterial agent that is distinguished by its activity against: Corynebacterium spp., Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Ureaplasma urealyticum.

The dosage of the drug is individual, therefore it is established by the attending physician. In addition to intestinal inflammation, Polizinax is also used to treat vaginal infections in women. The therapy lasts up to twelve days. Can be used as a prophylaxis (6 days).

There are no special contraindications for the use of these suppositories, but their use may cause allergy.

Meratin-Combi. The drug is based on the active components of nystanine, ornidazole, prednisolone and neomycin sulfate.

It is recommended to enter deep enough once in 24 hours (preferably at night). After the introduction, it is worthwhile to lie down for a little (at least fifteen minutes). The average therapy lasts about ten days.

There are no contraindications to the use of the drug, but it should be noted that Meratin-Combi in some cases can cause allergic reactions or irritations.

Mikozhinax. The drug is based on the active components of nystanine, chloramphenicol, metronidazole, dexamethasone acetate.

The standard dosage of the agent is as follows: one suppository is administered once a day. The duration of therapy is determined by a specialist, but it should not exceed ten days.

Absolute contraindication to the use of these suppositories are the following diseases: lactation, treatment of pregnant women, allergy to any of the components of the drug, treatment of children.

Mikozhinax can cause diarrhea, inflammation of the mouth, hepatitis, pancreatitis, encephalopathy, agranulocytosis, pustular rash, nystagmus, diplopia, headaches.

trusted-source[13], [14]

Anti-inflammatory rectal suppository in proctology

The most common disease in which a rectal suppository with an anti-inflammatory effect is used is hemorrhoids. They are usually made using synthetic and natural components. The most popular vegetable components are: calendula, propolis, sea buckthorn oil. Among the effective suppositories in proctology should be allocated: Proctosan, Neo-Anusole, Anuzol and Procto-Glivenol.

Proctosan. The drug is based on the active components of titanium dioxide, bufexamak, lidocaine hydrochloride monohydrate, bismuth subgallate. It differs in astringent, anesthetic, anti-inflammatory, drying effect.

The dosage of suppositories is as follows: one suppository is injected deep enough into the anus to two times in 24 hours. It is very important to put the drug after the intestine has been emptied. The therapy lasts up to ten days, there is no need to stop treatment after the disappearance of visible symptoms of the disease and improvement of the general condition.

Proctosus is not recommended for tuberculosis or syphilis. Do not treat with these pills hemorrhoids during pregnancy or breastfeeding. Not used to treat children. Taking Proctosan can cause allergies, itching, burning.

Neo-Anusol. The medicine is based on the active components of tannin, bismuth nitrate, resorcinol, zinc oxide, iodine, methylthioninium chloride. It has an astringent and antiseptic effect.

The standard dosage consists of one suppository once or twice a day. There are practically no contraindications to the use of the drug, but it should be noted that Neo-Anusolum can cause allergies.

Anusole. The medicine is based on the active components of zinc sulphate, bismuth tribromophenate, thick extract of belladonna. It differs in antiseptic, anti-inflammatory, analgesic, astringent, antispasmodic, drying effect.

The standard dosage is one suppository not more than twice a day. It is worth noting that you can not use more than seven suppositories per day (only by appointment of a specialist).

Anusole is not recommended for use with tachyarrhythmia, intestinal atony, zakratougolnoy glaucoma, myasthenia gravis, prostate adenoma. Do not use to treat children, pregnant women, women during lactation. It can cause weakening of the stool, headaches, dry mouth, constipation, and increased heart rate.

Procto-Glivenol. Drug based on the active components of lidocaine and tribenozide. Quickly removes the main symptoms of hemorrhoids.

The standard dosage is one suppository twice in 24 hours (preferably in the morning and in the evening). When there is a regression of symptoms, you can use it once a day. It is not recommended to use for the treatment of pregnant women and children. Do not take with liver disease.

Procto-Glivenol can cause the development of allergic reactions, bronchospasm, anaphylactic reactions, puffiness, skin irritation.

Consider pharmacodynamics and pharmacokinetics of rectal anti-inflammatory suppositories on the basis of Procto-Glivenol.


This drug is considered a combined drug for the treatment of hemorrhoids. Tribenozid, which is a part of suppositories, helps improve the tone of blood vessels and the permeability of capillaries. It also acts antagonistically on endogenous substances, which take part in the onset of pain and the development of inflammation.

With the second active component, lidocaine, Procto-Glivenol differs anesthetic effect.

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  1. Myasthenia gravis.
  2. Prostate adenoma.
  3. Closed-angle glaucoma.
  4. Childhood.
  5. Pregnancy and lactation.
  6. Tachyarrhythmia.
  7. Syphilis or tuberculosis.
  8. Dermatitis.
  9. Allergy.
  10. Crohn's disease.

trusted-source[23], [24], [25]

Side effects of the rectal anti-inflammatory suppositories

  1. Headache.
  2. Constipation.
  3. Diarrhea.
  4. Skin irritation.
  5. Increased palpitations.
  6. Photosensitivity.
  7. Dryness in the mouth.
  8. Agranulocytosis.
  9. Pancreatitis.
  10. Hepatitis.

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Sometimes an overdose of rectal anti-inflammatory suppositories, in which the patient has constipation or diarrhea. Symptomatic therapy is used to improve the condition. Use of the drug is discontinued.

trusted-source[29], [30]

Storage conditions

It is very important to store suppositories with an anti-inflammatory effect in a place that is inaccessible to young children. The air temperature should not exceed +30 degrees. In some cases, the drug should be stored in the refrigerator.

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Shelf life

As a rule, the shelf life of such medicines is five years.

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To simplify the perception of information, this instruction for use of the drug "Rectal anti-inflammatory suppositories" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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