To inject an injection of a medicine it is necessary slowly, a method p / to. To conduct the procedure better in the evening. The drug is diluted in 1 ml of solvent (form of release 1.3 (4 IU) or 2.6 mg (8 IU)) or in 2 ml of solvent (form of release 5.3 (16 IU) or 8 mg (24 IU) )). The procedure is performed by removing the solvent with a syringe - and then introducing it into the container with the medicine through the plug. It is required to wait for complete dissolution of the drug. Do not shake the bottle sharply.
The dosage is selected individually - the weight or the surface area of the patient, the degree of hormone deficiency, and the effectiveness of the medicine used are taken into account.
To eliminate the lack of somatotropin, adults need to administer the initial dosage once a day (0.006 mg / kg (or 0.018 IU / kg)), and then, taking into account the effect of drugs, increase it to 0.012 mg / kg (or 0.036 IU / kg), also once per day. For the elderly, doses should be reduced.
In case of growth disorders due to inadequate release of somatotropin, children should be administered 0.025-0.035 mg / kg (or 0.07-0.1 IU / kg) or 0.7-1 mg / m (or 2-3 IU / m²) once per day day. When you get the desired effect, you can finish the therapy.
It is necessary to begin the course of treatment as soon as possible after the diagnosis and conduct it until:
- the growth rate during therapy will not decrease to a level of 2 cm / year or less;
- there will be no closure of epiphyseal growth areas;
- a socially acceptable growth rate (for girls it is about 155-160 cm, and for boys - about 165-170 cm) will not be achieved;
- will not reach the bone age (for girls - about 14-15 years, and for boys - about 16-17 years).
With the development of STH deficiency during childhood and its preservation during the adolescent period, it is necessary to continue therapy until there is a complete somatic development (bone mass and body structure).
Problems with growth in the syndrome Ulrich. Pediatric renal failure is a chronic type, in which there is a growth retardation.
It is required to administer the drug in the amount of 0.05 mg / kg (or 0.14 IU / kg) or 1.4 mg / m (or 4.3 IU / m²) once a day. If the growth dynamics of growth are insufficient, correction of the dose size may be necessary.