Pumpkin seed oil

Pumpkin seed oil is part of the group of lipid-lowering medications.

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Indications of the pumpkin seed oil

It is used to prevent the development of atherosclerosis in the heart and cerebral vessels, and in addition hyperlipidemia (forms 2a and 2c). It is also prescribed for combination therapy and prevention of benign prostatic hyperplasia (grade 1 and 2).

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Release form

The release is carried out in the form of oil, in flakonchikah volume of 50 or 100 ml. Inside the box - 1 bottle.

[3], [4], [5]

Pharmacodynamics

The medicine contains a whole complex of bioactive components that are constituent elements of pumpkin seeds (among them are tocopherols with carotenoids, phosphatides and phospholipids, as well as flavonoids, thiamines, riboflavins, bioflavonoids, niacins, vitamins C and F, and in addition fatty acids (unsaturated, semisaturated , as well as polyunsaturated), among which octadecane, hexadecane, oleic, linoleic and linolenic, as well as arachidonic). They have anti-inflammatory, choleretic, antioxidant, hepatoprotective, and also anti-sclerotic properties.

Element phosphatidylcholine, an activator of the enzyme LHAT, converts free cholesterol into its esters, not involved in the development of atherosclerosis. At the same time, this element penetrates into the composition of high-density lipoproteins, helping to accelerate the movement of cholesterol within the endothelial membrane together with platelets, preventing aggregation of the latter. In addition, fatty acids of unsaturated type slow down the absorption of cholesterol, and also increase the excretion of fatty acids.

The medicine helps to improve the activity of the ZHVP, corrects the chemical component of bile, has a weak choleretic effect, weakens the developing inside the epithelium of the biliary excretory system of inflammation. It also reduces puffiness, speeds up the process of epithelialization and improves microcirculation, has a protective effect on granulation, and also helps exchange and trophic processes inside tissues.

The oil has antihypertensive properties, suppresses cell proliferation inside the prostate with the development of benign hyperplasia, and also reduces the severity of inflammation and has a weak bacteriostatic effect.

[6], [7]

Dosing and administration

Oil is used orally.

Adults - as a prophylactic against hyperlipidemia, you need to drink a 1-ounce teaspoon of oil twice a day. Usually this course lasts 2 months. Next, you need to drink 0.5 teaspoon twice a day. The duration of this course is determined by the course of the pathology and its severity, and on average is 0.5 years.

In the treatment of prostate hyperplasia, one teaspoon should be drunk twice a day in about 4-5 weeks (on average), and then one-time intake of 0.5 teaspoon per day. The duration of therapy is prescribed by a doctor, often 5 months.

[10], [11], [12], [13], [14]

Use of the pumpkin seed oil during pregnancy

There is no information on the effectiveness of drug use and its safety in prescribing to nursing or pregnant women. Therefore, it is forbidden to apply it during these periods.

Contraindications

The main contraindications:

• the presence of hypersensitivity to the drug;
• combined use with antacids;
• cholelithiasis pathology;
• pancreatitis;
• children's age, because there is no data on the safety of use of drugs in this category of persons.

[8], [9]

Side effects of the pumpkin seed oil

Due to prolonged intake of oil, sometimes allergy symptoms or loose stools develop.

At occurrence of any collateral attributes it is required to consult at once to the doctor.

Overdose

Signs of intoxication: sensation of weakness and diarrhea.

If the patient develops such symptoms, it is necessary to cancel the use of the medicine. Further, procedures for symptomatic treatment are performed.

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Interactions with other drugs

Antacids, histamine blocking agents (H2), proton pump inhibitors and bismuth drugs decrease the absorption of pumpkin oil and weaken its effect.

You must notify your doctor if you take any other medicines with pumpkin oil.

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Storage conditions

Pumpkin seed oil is required to be kept out of the reach of children. The temperature is in the range of 8-15 ° C.

[21], [22], [23]

Shelf life

Pumpkin seed oil is allowed to be used for 2 years from the date of release of the drug.

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