Potassium permanganate

Potassium permanganate is a disinfectant. It is a powder for making a solution for external use.

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Indications Potassium permanganate

Among the main indications: disinfection of burns with ulcers, as well as infected wounds. In case of infectious inflammation of the oropharynx and oral mucosa (for example, tonsillitis) - used for rinsing. In case of urogynecological diseases (urethritis, and in addition colpitis) used for douching or washing the area.

It can also be used for gastric lavage: in case of poisoning with orally taken alkaloids (such as nicotine with morphine or aconitine), quinine and phosphorus, as well as hydrocyanic acid. It can be used to wash the skin after contact with phenylamine; and the eyes in case of intoxication with insect venom.

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Release form

It is produced in powder form (volume 3 g) in jars, as well as glass bottles or test tubes, and in addition, in polyethylene bags.

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Pharmacodynamics

After interaction with various organic compounds, the active substance produces atomic oxygen. As a result of the reduction of potassium permanganate, MnO2 is formed, which, together with proteins, creates albuminates. As a result, the preparation in small concentrations acquires astringent properties, and when forming an aqueous highly concentrated solution, it acquires cauterizing, and at the same time tanning, as well as irritating properties. In addition, it has a deodorizing effect.

Since potassium permanganate is capable of neutralizing certain poisons, its solution is often used for gastric lavage in cases of intoxication.

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Pharmacokinetics

When taken internally, it is quickly absorbed, causing a hematotoxic effect (promoting the development of methemoglobinemia).

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Dosing and administration

The medicine should be used externally as a disinfectant solution for wounds (concentration 0.1-0.5%), and in addition to this as a means for gargling the throat and mouth (concentration 0.01-0.1%), treating burns with ulcers (concentration 2-5%), douching for urogynecological diseases (concentration 0.02-0.1%), and in addition to this for gastric lavage in case of intoxication.

To dissolve this powder, you need to put a few crystals in warm water (a glass), and then stir until completely dissolved. This solution can only be used freshly prepared.

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Contraindications

It is contraindicated to use the medicine in case of individual intolerance to it.

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Side effects Potassium permanganate

Side effects include: allergy; if a concentrated solution is used, irritation and burns may occur on the skin.

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Overdose

Overdose symptoms include: sharp, severe pain in the mouth, throughout the digestive tract and abdomen, as well as diarrhea and vomiting. The mucous membrane in the mouth and throat swells and becomes purple or dark brown. Laryngeal edema may occur, mechanical asphyxia may begin, and psychomotor agitation or shock from a burn, parkinsonism or dysentery may develop. In addition, seizures and nephropathy may occur. If gastric secretion has reduced acidity, there is a possibility of increased methemoglobin levels in the blood with noticeable dyspnea and cyanosis. For a child, the lethal dose is approximately 3 g, and for an adult - 0.3-0.5 grams / kg.

For treatment, a solution of methylene blue is used (50 ml of a 1% solution is required), vitamin C (IV 5% solution with a dosage of 30 ml), vitamin B12 (maximum 1 mg), and vitamin B6 (IM 5% solution with a dosage of 3 ml).

Interactions with other drugs

Potassium permanganate cannot be combined with individual organic compounds (such as sugar with coal, and also tannin) and substances that oxidize quickly. As a result of such a combination, an explosion may occur.

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Storage conditions

The powder should be kept in a dry place, out of reach of children. Temperature conditions should be within 15-18°C.

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Shelf life

Potassium permanganate is permitted to be used for 5 years from the date of manufacture.

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