Potassium permanganate

Potassium permanganate is a disinfectant. It is a powder for making a solution applied externally.

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Indications Potassium permanganate

Among the main indications: disinfection of burns with ulcers, as well as infected wounds. In the case of infectious inflammation of the oropharynx and oral mucosa (eg, angina) - is used for rinsing. With urogynecological diseases (urethritis, and in addition colpitis) is used for douching or rinsing this area.

It can also be used for gastric lavage: in case of poisoning with orally taken alkaloids (such as nicotine with morphine or aconitine), quinine and phosphorus, as well as cyanic acid. You can rinse the skin due to falling on it of phenylamine; and the eyes in case of insect poisoning into insects.

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Release form

Produced in the form of powder (3 g) in cans, as well as vials or test tubes made of glass, and besides this, plastic bags.

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Pharmacodynamics

After interaction with various organic compounds, the active substance produces atomic oxygen. As a result of the reduction of potassium permanganate, MnO2 is formed, which together with proteins creates albumins. As a result, the preparation receives astringent properties in small concentrations, and when forming an aqueous highly concentrated solution, cauterizing, and with it tanning, as well as annoying properties. In addition, it has a deodorant effect.

Since potassium permanganate is capable of neutralizing individual poisons, its solution is often used for gastric lavage during intoxication.

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Pharmacokinetics

In case of internal reception it is quickly absorbed, having thus a hematotoxic effect (promotes occurrence of a methemoglobinemia).

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Dosing and administration

Use the drug externally, as a disinfectant solution for wounds (concentration of 0.1-0.5%), and in addition as a means for rinsing the throat and mouth cavity (concentration 0.01-0.1%), treatment of burns with ulcers ( concentration of 2-5%), syringing with urogynecological diseases (concentration 0.02-0.1%), and in addition for gastric washing with intoxication.

To dissolve this powder, you need to place a little crystals in warm water (glass), and then mix until completely dissolved. Use this solution can be exclusively freshly prepared.

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Contraindications

It is contraindicated to use the medicine for individual intolerance to it.

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Side effects Potassium permanganate

Among the side effects: allergy; In case of applying a concentrated solution on the skin, irritation occurs along with burns.

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Overdose

Among the manifestations of an overdose: a sharp severe pain in the mouth, throughout the digestive tract and in the abdomen, as well as diarrhea with vomiting. Thus the mucous in a mouth and a pharynx swells, gets violet or dark-brown shade. A laryngeal edema may occur, mechanical asphyxia may begin, and in addition to this, psychomotor agitation or a shock condition from a burn, parkinsonism or dysentery may develop. In addition, there may be seizures and nephropathy. If the gastric secretion has a reduced acidity, there is the possibility of increasing the level of methemoglobin in the blood with a noticeable dyspnea and cyanosis. For a child, the lethal dosage is approximately 3 grams, and for an adult - 0.3-0.5 grams / kg.

A solution of methylene blue (50 ml of 1% solution), vitamin C group (iv 5% solution with a dosage of 30 ml), vitamin B12 (maximum 1 mg), as well as vitamin B6 ( in / m 5% solution with a dosage of 3 ml).

Interactions with other drugs

Potassium permanganate can not be combined with individual organic compounds (such as sugar with coal, but in addition tannin) and substances that are rapidly oxidized. Due to such a connection, an explosion may occur.

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Storage conditions

Keep the powder in a dry place that will not be accessible to children. The temperature conditions are within 15-18 ° C.

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Shelf life

Potassium permanganate is allowed to be used for 5 years from the date of manufacture.

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