Pedilin

Pedilin is a medicine that destroys ectoparasites. The active component of the medicine is malathion. The drug belongs to the category of insecticides of organophosphorus nature and has anti-pediculosis properties.

The shampoo contains the insecticide permethrin, which is an artificial pyrethroid. The substance quickly gets into the parasites' nervous system. It is a contact poison for many arthropods, repolarizing the walls of nerve cells, and at the same time affects their nervous system, leading to paralysis and death of the parasites. The effect of the drug begins very quickly, and due to the long-term preservation of the drug on the hair, the likelihood of re-infection is prevented.

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Indications Pedilina

It is used in people with pediculosis – both children and adults.

Release form

The medicinal product is released in the form of shampoo, in 100 ml bottles.

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Pharmacodynamics

The drug passes through the chitin barrier without complications, reaching high values inside the parasite's body, and at the same time irreversibly slows down the enzyme cholinesterase, creating a covalent bond with it. Nits with lice die due to self-intoxication with acetylcholine.

Pharmacokinetics

After local use, less than 2% of the applied permethrin is absorbed, which is why its overall toxicity remains very low. The effect of the shampoo continues to persist for 0.5-1.5 months after a single treatment.

Dosing and administration

The shampoo should be applied to wet hair - rub it into the scalp for 3 minutes, then rinse the hair thoroughly under running warm water and repeat this procedure again. Then comb the hair using a special comb.

If necessary, the treatment procedure can be repeated after 7 days. To prevent relapse of pediculosis, all inhabitants of the house should be treated with shampoo.

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Use Pedilina during pregnancy

Pregnant or breastfeeding patients can use Pedilin only in situations where the potential benefit from it is more expected than the risk of negative consequences for the fetus or infant.

Contraindications

Contraindicated for use in people with severe sensitivity to the components of the medication.

Side effects Pedilina

The use of Pedilin may lead to the appearance of various signs of allergy.

Overdose

Long-term inhalation of the drug or prolonged contact of the substance with the epidermis leads to excitation of n- and m-cholinergic receptors, and along with this, signs of overdose are noted: urinary incontinence, cyanosis, vomiting with intestinal colic, weakness affecting the limbs, convulsions, nausea, respiratory disorders, instability of blood pressure, muscle twitching, and in addition bradycardia or tachycardia, hypersalivation and hyperhidrosis, as well as visual disturbances and lacrimation.

If the shampoo has been in contact with the epidermis for a long time, it is necessary to thoroughly wash these areas with water and soap, and in addition to this, use atropine with diazepam to reduce the feeling of anxiety and muscle twitching.

In case of oral administration of the drug, gastric lavage should be performed; it is also necessary to seek medical help.

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Storage conditions

Pedilin should be stored in a place inaccessible to children. Temperature indicators - no higher than 25°C.

Shelf life

Pedilin can be used for a 2-year period from the date of manufacture of the medication.

Application for children

It is prohibited to prescribe to children under 2 years of age.

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Analogues

The analogs of the drug are Permethrin with Hygia, as well as Nittifor with Permethrin ointment.

Reviews

Pedilin gets good reviews from patients – it is believed to cope well with the destruction of lice. Of the minuses – manifestations of an allergy to the shampoo may be noted.