Medical expert of the article
New publications
Preparations
Phenotropil
Last reviewed: 04.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Indications Phenotropil
It is used to treat the following disorders:
- various diseases affecting the function of the central nervous system, especially those in which there is a disorder of the cerebral blood supply or metabolic processes;
- problems with attention and memory impairment;
- certain forms of schizophrenia (for example, a feeling of apathy and lethargy as a side symptom of the disease);
- alcoholism;
- under increased physical or mental stress;
- depressive states of varying severity;
- stabilization of biorhythms;
- obesity of alimentary-constitutional nature.
Release form
The release is made in tablets. Inside the box there are 10 or 30 pieces.
[ 3 ]
Pharmacodynamics
The drug helps improve the learning process due to its positive effect on memory. Reduces the toxic properties of certain drugs, as well as the hypnotic effect of hexobarbital and ethyl alcohol. In addition, it helps improve a bad mood, reduces the pain threshold and increases physical performance.
It helps improve cerebral blood supply, and also stabilizes and activates oxidation-reduction processes inside the brain. At the same time, it helps stabilize regional cerebral blood flow in ischemic areas. In addition, there is an improvement in blood supply in the leg area.
Without affecting spontaneous bioelectric brain activity and GABA indices, the drug increases dopamine and adrenaline levels, as well as serotonin and noradrenaline. This helps improve mood and general condition.
Long-term use of the drug leads to the development of an anorectic effect. Phenotropil has some immunostimulating properties, and in addition, it has a positive effect on vision.
The drug does not have a mutagenic or carcinogenic effect, and does not have an embryostatic effect.
The effect of the drug begins from the moment of the first use. The critical dose leading to death is 0.8 g.
[ 4 ]
Pharmacokinetics
After penetration into the gastrointestinal tract, the substance is fully and rapidly absorbed. The Cmax level in the blood plasma is noted after 60 minutes, and the excretion of the unchanged component occurs after 3-5 hours - with urine (about 40%), as well as with sweat and bile (approximately 60%). It is not subject to metabolic processes.
Dosing and administration
Before you start using the medication, you should consult with your doctor so that he can prescribe the appropriate dose and duration of the treatment cycle.
The drug is taken orally - the tablet is taken after meals, along with plain water. It is recommended to do this in the morning. A maximum of 0.75 g of the substance is allowed per day. On average, 0.1-0.25 or 0.2-0.3 g/day is allowed once. If the 0.1 g mark for a single portion is exceeded, it must be divided into 2 uses.
For the treatment of obesity, 0.1-0.2 g of the drug should be used once a day (in the morning). The cycle lasts about 1-2 months.
To increase performance, take 0.1-0.2 g of the drug in the morning for 15 days.
The therapy usually lasts about 1 month (on average). The maximum permissible duration of the cycle is 3 months. If necessary, a repeat course can be carried out (after 30 days).
Use Phenotropil during pregnancy
Phenotropil should not be prescribed to pregnant or lactating women.
Contraindications
Contraindication is the presence of individual hypersensitivity to the components of the drug.
The drug is used with extreme caution in children, as well as in people with organic renal/hepatic lesions, elevated blood pressure, and severe coronary heart disease. At the same time, it is prescribed with extreme caution to people suffering from acute psychopathic disorders or who have experienced panic attacks.
[ 7 ]
Side effects Phenotropil
Most often, taking medications causes the development of insomnia (usually in the case of taking medications 6-8 hours before bedtime).
It is also possible that blood pressure may increase, and in addition, psychomotor agitation or unexpected hot flashes may develop.
[ 8 ]
Overdose
Intoxication may cause potentiation of negative symptoms. No cases of drug overdose have been reported so far.
Therapy is carried out taking into account the symptoms that appear.
Interactions with other drugs
Phenotropil potentiates the effectiveness of medications that affect the functioning of the central nervous system, as well as various antidepressants and other nootropic drugs.
[ 12 ]
Storage conditions
Phenotropil may be kept in places closed to small children and sunlight. Temperature values are a maximum of 30°C.
[ 13 ]
Shelf life
Phenotropil can be used within 5 years from the date of manufacture of the drug.
Analogues
The substances glycine and piracetam (or nootropil) are considered analogs of the drug.
[ 14 ]
Attention!
To simplify the perception of information, this instruction for use of the drug "Phenotropil" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.