Panthenol Spray

Panthenol Spray is a medicine with a local anti-inflammatory, as well as dermatoprotective effect. It replenishes the lack of vitamin B5, and also stimulates healing processes.

Indications of the panthenol Spray

It is used in such situations:

• to accelerate the epithelization and regeneration of the skin after the resulting microtraumas or skin grafts, and in addition, with irritation (for example, due to the influence of radio or phototherapy and UV rays), eruptions of the uterine neck, pressure sores, cracks in the anus and skin ulcers of a chronic nature;
• for therapy with mild burns;
• to eliminate the cracking and roughness of the skin, or to prevent these disorders;
• as a preventive agent in the treatment of mammary glands in mothers during lactation, and in addition - to ease irritation in the nipple and eliminate the cracks formed on them;
• permanent treatment of the skin in infants and therapy with gluteal erythema (the so-called diaper dermatitis);
• treatment of the skin surface in people using the local form of SCS (or after their use).

[1], [2]

Release form

The release is carried out in the form of a spray in cans of 130 g. In a pack - 1 such a can.

Pharmacodynamics

Dexpanthenol is an alcohol analog of vitamin B5, which, after biotransformation within the body, has the same effect as the pantothenate itself.

After getting on the surface of the skin, the active ingredient is quickly absorbed into the tissues, transforming into its active form - vitamin B5 (a substance from the water-soluble group). This element is an integral component of the specific CoA coenzyme, the main regulator of metabolic processes (fat, protein, carbohydrate, phospholipid exchange and fatty acid metabolism, and besides this, the citrate cycle, etc.). It promotes the processes of formation of corticosteroids and acetylation of the choline element.

Pantothenic acid with dexpanthenol, as well as their anhydrous salts are vitamins of water-soluble type. These elements are active participants in carbohydrate, fat, and energy metabolism and are extremely important in the performance of acetylation and oxidation.

During metabolic processes, this component interacts with the B vitamins included in the B category. Promotes the formation of epithelial tissues and helps their stable function. In addition, it weakens the itching and has a weak anti-inflammatory effect.

After local treatment, the medicine compensates for the increased need for pantothenate on the damaged skin area or mucous membranes.

[3], [4]

Pharmacokinetics

The active ingredient is absorbed into the skin.

In an adult healthy person, after a local drug use, the level of pantothenate in the blood reaches 0.5-1 mg / ml, and within the blood serum - 0.1 mg / ml.

The active element is not metabolized inside the body (with the exception of entering the CoA system). Approximately ⅔ of intact organism of unmodified pantothenate (about 70%) is excreted by the kidneys, and the remainder - along with feces.

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Dosing and administration

Spray is used once (or several times, if there is such a need) for a day, evenly treating them with the affected area of the skin (should be completely covered with foam). The balloon should be kept at a distance of 10-20 cm.

The duration of the course is determined by the severity of the treated pathology.

For burns spray should be used no more than 6 times / day. To eliminate wounds, the drug is applied to the affected area with a thin film - the procedure is performed 1-5 times / day.

During the spraying of the medicine, the can should be placed vertically, with the valve upward. For better application of medicines, it is necessary to shake the can before each use (especially if it has not been used before).

When using the spray for the first time, one should expect that at first, before the appearance of foam, the spraying will be carried out in the form of a propellant.

If you need to use a facial treatment, spray the spray on your arm, then apply foam to the affected area of the skin.

During the treatment of mild burns (grade 1-2), Panthenol in the form of a spray is most suitable at the initial stages of the treatment course. The burned part of the skin needs to be treated immediately after getting the damage, and then use the spray taking into account the need (approximately 1-4 procedures per day are required).

Before using the spray to treat the wound surface, you must first disinfect this area.

Use of the panthenol Spray during pregnancy

If there are indications, Panthenol spray can be used by pregnant women (at any time), as well as by nursing women.

Contraindications

Contraindication is hypersensitivity to dexpanthenol or additional elements contained in the drug.

Side effects of the panthenol Spray

A side symptom of using drugs may be manifestations of hypersensitivity.

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Interactions with other drugs

In the case of Panthenol Spray treatment of the anal area or genitals, the strength of condoms can be reduced when they are used. This is due to the fact that this form of the drug contains mineral oil in its composition.

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Storage conditions

Panthenol spray is required to be kept in a place that is closed from sunlight, and also inaccessible to children. Temperature indices - not more than 25 ° C.

[9], [10], [11]

Special instructions

Reviews

Panthenol Spray is a universal remedy that helps with the healing of burns and various injuries.

In addition, often there are reviews on the high effectiveness of the spray as a remedy for dryness of the skin and wrinkles. Women are advised to treat them pre-steamed face - the resulting pores allow you to absorb more useful substances, thereby increasing the effectiveness of the drug.

[12]

Shelf life

Panthenol spray can be used for 2 years from the date of release of the drug.

[13], [14],