Pantestin

Pantestin has antimicrobial and reparative effects.

Indications Pantestina

It is used in the following cases:

• for diaper dermatitis, as well as diaper rash;
• for bedsores and ulcerative lesions of the trophic type;
• for the treatment of granulating burns;
• for the treatment of lesions of the oral mucosa, ulcerative-necrotic form of gingivitis, as well as periodontitis and aphthous form of stomatitis;
• in case of radiation damage to the skin surface, as well as mucous membranes;
• for the treatment of neurodermatitis or eczema of an infected nature;
• in case of colpitis or erosion of the cervix;
• for minor cuts, abrasions, and scratches;
• to eliminate sunburn.

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Release form

It is released in gel form and tubes.

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Pharmacodynamics

The active ingredient of the drug D-panthenol is a provitamin that penetrates into skin cells, where it is converted into pantothenate (a component of coenzyme A). It is a direct participant in the processes of binding materials that form new cells.

Dexpanthenol stimulates healing processes, and in addition regulates energy metabolism within epithelial cells. The substance has a positive effect on the binding of mucopolysaccharides, as well as fatty acids (these elements are important parts of connective tissues). This, in turn, accelerates the healing of the skin and complicated wound surfaces.

An important property of the medicine is its antibacterial and antimycotic activity, provided by the antiseptic substance - miramistin. Most pathogenic microbes infecting wound surfaces do not have high resistance to this element. The antimicrobial effect of miramistin promotes the healing of infectious processes inside the wound and complements the action of the element D-panthenol.

The combined agent has an epithelializing, antibacterial, wound-healing, and fungicidal effect.

Pharmacokinetics

Metabolism of dexpanthenol occurs at the site of gel application, the substance does not penetrate into the circulatory system. Miramistin is also not absorbed into the bloodstream, remaining only on the surface of the wound.

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Dosing and administration

The gel must be used locally.

When used after surgical procedures, apply a thin layer to the wound and then apply a gauze bandage on top.

In dermatology, the drug is used 2-3 times a day. In this case, it is possible to refuse the use of bandages.

In gynecology, it is necessary to soak a gauze tampon in gel and then insert it into the vagina.

In pediatrics, the use of the gel is allowed for the treatment of skin lesions in newborns from the first days of the child's life. The treatment should be performed during each change of the baby's diaper. The duration of the course is determined by the severity of the symptoms of the disease.

In dentistry, it is only allowed to treat diseases affecting the oral cavity with Pantestin for adults. After performing hygienic procedures, it is necessary to apply a thin layer of the drug to the affected area of the oral mucosa. The procedure should be performed 2-3 times a day. It is forbidden to eat for 1 hour after the procedure. During the treatment of the prosthetic form of stomatitis, a denture should be inserted immediately after treating the mouth with gel. The treatment should last for 10 days.

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Use Pantestina during pregnancy

Pregnant and lactating women are allowed to use the gel, but only on small areas of the body.

Contraindications

Main contraindications:

• the presence of intolerance to the elements of the drug;
• severe degree of purulent exudation;
• applications in the area of the eardrums when they are perforated.

Side effects Pantestina

Among the side effects of the gel is the rare development of allergy symptoms. When applying to burns or wounds, a slight burning sensation sometimes appears, which disappears on its own, without requiring discontinuation of the drug.

If the patient develops skin irritation (of any severity), as well as hyperemia, itching, swelling, eczema or weeping lesions, the use of the medicine should be discontinued.

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Interactions with other drugs

It is forbidden to combine with other antiseptics, because these agents inactivate the effect of miramistin.

Dexpanthenol potentiates the effectiveness of muscle relaxants (such as decamethonium bromide or suxamethonium chloride) due to its stimulating effect on the process of acetylcholine binding.

Combined use of the drug with soap solutions inactivates the properties of miramistin. When combined with systemic antibiotics, the resistance of microbes to antibiotics decreases.

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Storage conditions

Pantestin should be stored in a place protected from moisture. The gel should not be frozen. Temperature – maximum 25°C.

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Special instructions

Reviews

Pantestin has a wound-healing effect, so it is used to treat wounds (at the 2nd-3rd stage of their development). The gel protects the wound or burn surface from the possibility of secondary infection, and in addition, it activates metabolic processes and stimulates the process of tissue blood supply and wound healing (under the influence of dexpanthenol).

Miramistin is a powerful antiseptic and acts on fungi and bacteria that often penetrate the wound and infect it.

Such a composition allows replacing several separate drugs with different types of therapeutic effects. The potentiation of the therapeutic effect of the gel is facilitated by its special synthetic base, which helps active substances penetrate deep into the tissues and increases the period of action of the drug. An important property of dexpanthenol is its ability to prevent the contraction of the skin at the edges of the wound, thereby preventing the risk of rough scars.

Due to these characteristics, the drug receives many positive reviews.

Shelf life

Pantestin can be used for 2 years from the date of manufacture of the drug.