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Pancreatic tumors with carcinoid syndrome

 
, medical expert
Last reviewed: 07.07.2025
 
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In most cases, they are found in the intestines in the ileocecal angle and in the bronchi, but are rarely functional.

Pancreatic carcinoid is capable of secreting almost all peptides characteristic of ortho- and paraendocrine neoplasms.

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Symptoms pancreatic tumors with carcinoid syndrome.

Carcinoid syndrome is caused by the secretion of biogenic amines and is clinically manifested by hot flashes, tachycardia, diarrhea and attacks of bronchial asthma. The presence of clinical manifestations indicates that biogenic amines have overcome the liver barrier as a result of the metastatic process.

Where does it hurt?

Diagnostics pancreatic tumors with carcinoid syndrome.

Laboratory diagnostics reveal high levels of serotonin, histamine and 5-hydroxytryptophan in the blood of patients, as well as increased excretion of 5-hydroxyindoleacetic acid in the urine.

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Treatment pancreatic tumors with carcinoid syndrome.

Drug treatment of carcinoid syndrome involves the combined use of histamine H1- and H2-receptor antagonists or methyldopa. There are observations of a positive effect from the use of somatostatin.

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