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Palprostes
Last reviewed: 03.07.2025
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Palprostes is a drug that regulates the functions of the male genitourinary system. ATC code G04C X02. Other trade names: Prostaplant, Prostaker, Unoprost, etc.
Indications Palprostes
Indications for the use of Palprostes are: prostatitis, prostate adenoma (I and II degrees), as well as functional urination disorders in men associated with an enlarged prostate gland.
Release form
Release form: soft capsules of 320 mg.
Pharmacodynamics
The pharmacodynamics of Palprostes is based on the action of the active substance of the drug - an extract from the fruits of one of the species of fan palms of the genus Sabal - the finely serrated palm Sabal Serrulata.
The extract's phytosterols affect the metabolism of the endogenous male hormone testosterone. By blocking the human steroidogenesis enzyme, 5-alpha-reductase, the process of testosterone biotransformation into dihydrotestosterone, a powerful stimulator of prostate cell proliferation, slows down. In addition, by activating the enzyme 3α-hydroxysteroid oxidoreductase, which regulates the metabolism of dihydrotestosterone, its level in the prostate tissues decreases. This does not reduce the pathological growth of the prostate, but significantly alleviates the symptoms associated with its hyperplasia.
The probable (not clinically proven) ability of Palprotes to reduce the intensity of the inflammatory process in the prostate and relieve swelling of its tissues is associated with the inhibitory effect of the biologically active components of the drug on the enzymes cyclooxygenase and 5-lipoxygenase, which are catalysts for the synthesis of inflammation mediators (prostaglandins).
Pharmacokinetics
After oral administration, the extract contained in Palprostes is rapidly absorbed in the gastrointestinal tract. The maximum concentration in the blood plasma is observed approximately 90 minutes after taking the drug.
Dosing and administration
Palprostes is taken orally - one capsule once a day (at the same time, after meals). The capsule should be swallowed whole with liquid.
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Use Palprostes during pregnancy
The use of Palprostes during pregnancy and in children is completely excluded, since the drug is used only for the treatment of adult men.
Contraindications
Palprostes should not be used in case of individual hypersensitivity to the active substance of the drug.
Side effects Palprostes
Side effects of the drug in the form of an allergic reaction may occur only in cases of increased sensitivity of patients or as a result of exceeding the recommended dose.
[ 1 ]
Overdose
Overdose results in gastrointestinal disorders: nausea and painful sensations in the abdomen.
Interactions with other drugs
To date, no clinically significant interactions of this drug with other drugs have been established.
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Storage conditions
Storage conditions: out of reach of children, at a temperature not exceeding +30°C.
Shelf life
The shelf life is 36 months.
Attention!
To simplify the perception of information, this instruction for use of the drug "Palprostes" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.