The active substance Pyremola has a high absorption rate and is adsorbed in the small intestine, getting into tissues with blood flow. About 20% of paracetamol binds to blood plasma proteins. The drug penetrates through the BBB (and enters the breast milk). Approximately 25 minutes after taking the therapeutic dose of Peyrenol, its maximum concentration is achieved.
Transformation of the drug occurs in the liver, and inactive metabolites are excreted from the body by the kidneys. Half-life is an average of three hours. Some of the active substance Pairolone is metabolized by removing from the molecule an acetyl group, resulting in the formation of an easily oxidizable isomer of aminophenol (paraaminophenol), which, with significant doses of the drug, has a toxic effect on the liver.