Painkillers for gastritis

Many diseases of the digestive tract (for example, gastritis) are accompanied by pain - aching, or cutting, spastic. Sometimes such pain can be tolerated, but in some cases it is necessary to take urgent measures - in particular, to take painkillers. Usually it is prescribed by the attending physician. But there may be situations when it is not possible to consult with a doctor. And then there is a question: what pills are suitable for inflamed mucosa? How to make that painkillers for gastritis do not harm, and effectively relieve painful symptoms?

What painkillers are okay for gastritis?

The usual, familiar to us painkillers - non-narcotic analgesics and non-steroidal anti-inflammatory drugs - in gastritis are not only useless, but also extremely harmful, as they can aggravate the condition of inflamed tissues and even cause serious complications. Such drugs are appropriate for arthritis, myositis, neuralgia, headache, but not for inflammatory processes in the stomach:

• Salicylates (aspirin, acelizine, salicylamide);
• Pyrazolone derivatives (analgin, butadione);
• aniline derivatives (paracetamol);
• preparations based on organic acids (ibuprofen, orthofen, indomethacin, mefenamic acid);
• oxicam (piroxicam).

In gastritis, the above drugs are contraindicated. Therefore, patients eliminate pain by affecting the cause of its occurrence. That is, to get rid of pain, it is necessary to relieve spasm, stabilize motility, remove harmful toxic substances from the body, normalize acidity, create a protective layer on the mucosa, etc. Thus, the doctor can prescribe any of the following medications for pain relief in gastritis:

• Prokinetic and antifoaming drugs - relieve pain by eliminating intestinal gases, suppressing their formation. Typical representatives of such remedies are Simethicone, Disflatil, etc.
• Sorbent means - accelerate the excretion of toxic, allergenic substances that support inflammatory processes in the digestive system. Among the most famous such drugs are Smecta, Enterosgel, activated charcoal.
• Antacids - reduce the degree of acidity of the stomach, enveloping, protecting from irritation and relieving pain. Such drugs include Almagel, Fosfalyugel, Maalox, Gastal and others.
• Antispasmodics - eliminate spasm and, as a consequence, spastic pain. The best known antispasmodics are Drotaverine (No-shpa), Papaverine.

Any of the medications are used only after they are prescribed by a doctor. Self-medication can lead to aggravation of the disease.

Painkillers for gastritis exacerbation

With a recurrence of gastritis most often turn to drugs belonging to the antacid series. Such medicines have the following properties:

• neutralize the negative effect of acid on inflamed mucosa;
• reduce peptic activity;
• envelopes, binds bile acids;
• increase mucus production, increase the production of prostaglandins;
• promote repair of damaged tissue;
• help relieve the pain.

The most common pain medications used in these situations are these pain medications:

• Maalox;
• Phosphalugel;
• Almagel;
• Gaviscon.

In addition, it is allowed to use antispasmodics, which reduce the tone of smooth muscles and thereby eliminate the painful syndrome. The best known antispasmodics are Papaverine g/x, Drotaverine.

Painkillers for erosive gastritis

As an analgesic for gastritis with erosions, antacids and enveloping agents are usually used. This is especially true in relation to gastritis with hypersecretion of acid. Appoint calcium carbonate, Almagel. In severe pain, the doctor can use Atropine, Metacin - that is, cholinolytic drugs of peripheral action.

Spasmolytic medications are used most often in gastritis with insufficient secretory activity. They can be taken orally or administered as intramuscular injections.

If the patient is in a serious condition, the doctor may prescribe such serious drugs as narcotic analgesics, such as Morphine or Promedol, in hospital conditions. Such drugs are not available in pharmacies: they are administered by a doctor in particularly severe cases, when it is impossible to control the pain by other means.

Indications Painkillers for gastritis

To treat pain in gastritis, it is necessary to first establish the form and variant of the course of the disease. The fact is that many varieties of gastritis are known, and each such variety requires a special approach and medications.

The main rule: it is necessary to treat not so much pain as the inflammatory process, simultaneously affecting the cause of pathology and using complex therapy. Some drugs should be aimed at eliminating symptoms, others - to protect the mucous layer of the stomach, and others should necessarily be directed to neutralize the cause of the problem. Only with combined therapy can qualitatively stop the relapse of gastritis and prevent its subsequent development.

The need for pain relief in gastritis occurs quite often, because the pain appears both in the acute form of the disease and in its chronic course. Most often painkillers are required in the recurrence of gastritis, with the formation of ulcer process, with hypersecretion of hydrochloric acid, tumors. Hunger and overeating, eating junk food can also cause pain with gastritis. However, before taking painkillers, you need to make sure that there are no contraindications to taking such drugs.

Release form

Pharmaceutical products such as stomach pain relievers and anti-inflammatory drugs are dispensed in different dosages and forms:

• tablets (coated or uncoated);
• capsules;
• injectable solutions;
• lyophilizates for preparation of solutions;
• oral drops;
• suspensions for internal administration (in bottles or sachets);
• gel for internal ingestion;
• powder in a sachet.

How to relieve pain in the stomach with gastritis, what form of medication to choose, the attending doctor decides. When prescribing this or that drug takes into account not only the individual peculiarities of the course of gastritis, but also the age of the patient, his general state of health and so on.

Titles

In addition to generalized recommendations concerning the regime of the day, rest and nutritional correction, gastritis requires mandatory drug therapy. The main goals of such treatment, in addition to pain relief, become:

• anti-inflammatory action (for this purpose, both phytopreparations and antispasmodics are used - for example, No-shpa);
• Adjustment of gastric secretion (medicines with stimulating or substituting function are indicated - for example, Panzinorm, Etimizol, Pepsin, etc.);
• correction of general digestive function (Pancreatin, Mezyme, Somilase, etc.);
• stimulation of regeneration (sea buckthorn oil, Carnitine, Riboxin, etc.).

Painkillers for gastritis are available in different dosages and dosage forms. These can be capsules, tablets, solutions for injection, suspensions, etc.

Analgesic injections for gastritis are prescribed only when the pain is particularly intense, or when vomiting and in other cases when oral medication becomes impossible. Most often, the doctor prescribes such injections of drugs:

• No-shpa is available not only in tablet form, but also as a solution for injection 20 mg/mL in ampoules of 2 ml (40 mg). The recommended daily amount is 40-240 mg intramuscularly, in 1-3 injections. In special cases, intravenous administration of the drug is possible.
• Kvamatel in the form of a prepared solution is administered intravenously, in the hospital. If possible, as early as possible, the patient is transferred to the tablet form of the drug. The usual injectable dose is 20 mg twice a day, intravenously (once every 12 hours).
• Papaverine is administered for acute gastric pain, as subcutaneous, intramuscular or intravenous injection. Subcutaneous or intramuscular administration is 0.5-2 ml of 2% solution. Intravenous administration is usually slow, in combination with sodium chloride (1 ml of papaverine + 10-20 ml of saline).
• Atropine is administered as an emergency for rapid pain relief. Subcutaneous, intravenous or intramuscular administration is possible. For an adult patient, the maximum single dose (p/k) is 1 mg, and the daily dose is 3 mg.

Pain pills for gastritis are categorized:

• means to improve digestive processes, eliminate heaviness and pain in the stomach (Gastenorm, Creon, Pangrol, Aphobasol, Festal, Mezim, Enzistal, Pancreatin);
• remedies that relieve pain caused by increased gas (Espumizan);
• drugs that relieve pain caused by spasm (No-casp, Drotaverine);
• means, analgesics for gastric hyperacidity (De-nol, Rennie).

In addition, some analgesic effect has normalizing and restorative drugs Omeprazole, Ranitidine, Cimetidine, Vicalin and so on.

Pharmacodynamics

Gastritis is a disease that appears as a result of various exo- and endogenous factors. The inflammatory reaction develops in the gastric mucosa and is characterized by a number of symptoms - in particular, pain. Depending on the variation of the course, on the localization of the painful focus, on the endoscopic picture, etc., gastritis is divided into acute and chronic, generalized, superficial, atrophic, erosive, hypo- or hypersecretory, etc., etc. From the type of disease largely depends on what painkiller for gastritis the doctor will prescribe.

The pharmaceutical properties of pain medications are generally as follows:

• have anti-inflammatory and analgesic effect, relieve spasm;
• correct secretory dysfunction;
• normalize the functionality of intestinal digestion;
• correct metabolic disorders in case of obvious gastro-pancreatic syndrome;
• restore motor function;
• activate the processes of mucosal tissue repair.

As a rule, for the treatment of gastritis and, in particular, for pain relief, complex therapy with the use of several medications at once is used.

Pharmacokinetics

Pharmacokinetic properties of analgesics for gastritis can be clearly considered on the example of the popular drug Almagel A.

The active composition of Almagel A is represented by Algeldrate (aluminum hydroxide gel), magnesium hydroxide, benzocaine.

• Algeldrate is absorbed only in a small amount, which has practically no effect on the concentration content of aluminum salts in the bloodstream. Distribution of the component is absent, metabolism does not occur. The substance is excreted with fecal matter.
• Magnesium hydroxide is absorbed to about 10% of the consumed amount, which also does not change the concentration of magnesium ions in the bloodstream. Distribution is local, metabolism does not occur. The compound is excreted with feces.
• The component Benzocaine is absorbed in a negligible amount, which practically does not affect the systemic action. The analgesic property becomes noticeable during the first minutes of taking the medicine.

In general, the effect of Almagel A is noted as early as three minutes after taking it. The duration of the effect depends on the fullness and rapidity of gastric emptying. If the remedy was taken on an empty stomach, then its effect will last about one hour. If the suspension was taken an hour after eating, the effect of the drug will last 2-3 hours.

Dosing and administration

Going to take in gastritis painkiller of this or that group, you need to remember both contraindications and side effects, and the need for careful adherence to the dosage.

• Cholinolytic drugs:
  • Platifylline (Palufin) is taken orally 3-5 mg (or 10-15 drops of 0.5% solution) up to three times a day, subcutaneously 1-2 ml of 0.2% solution up to twice a day, rectally one suppository twice a day.
  • Gangleron - take one capsule before meals, up to four times a day, or in injections, subcutaneously, 2 ml twice a day.
  • Gastrozem - take 0.25 g twice a day for 14-21 days.
  • Histodyl - taken orally at 0.2 g three times a day, with food.
• Antispasmodic drugs:
  • No-shpa, or Drotaverine take 2 tablets 3-4 times a day, not exceeding the daily amount of 400 mg.
  • Bendazole is administered as intravenous or intramuscular injections, 30 mg 2-3 times a day. The course of treatment can be continued for 1-2 weeks.
• Antacid remedies:
  • Maalox is prescribed two tablets up to 4 times a day.
  • Phosphalugel is taken 1-2 sachets up to four times a day.
  • Almagel A is taken 1-2 scoops up to 4 times a day 15 minutes before meals. The duration of treatment is 1 week.

Application for children

At the acute stage of gastritis children are prescribed strict bed rest, deprived of food for a period of eight to twelve hours - compliance with this rule is an important point for the treatment of the disease in general, and to eliminate pain. Further, children are transferred to a strict diet with meals in fractional portions.

In case of intense pain, antispasmodics and anti-acid drugs (antacids) are used. Specialists recommend following a treatment regimen with a combination of proton pump inhibitors, antibiotics and bismuth preparations:

• Omeprazole, Esomeprazole, Rabeprazole - 0.5-1 mg/kg, but not more than 20 mg, twice a day;
• Amoxicillin - 50 mg/kilogram, but no more than 1 g, twice a day;
• Clarithromycin - 15 mg/kilogram, but not more than 500 mg, twice a day;
• Metronidazole - 20 mg/kilogram, but no more than 500 mg, twice a day;
• De-nol (bismuth subcynate colloid) - 120 mg up to four times a day;
• Piloride (Ranitidine bismuth citrate) - 400 mg twice a day;
• Nifuratel at 10-30 mg/kg twice daily;
• Furazolidone 10 mg/kilogram per day, in 3-4 doses (no more than 200 mg per dose).

If pain in gastritis is caused by spasms and increased gastric motility, then the use of antispasmodics (Drotaverine, Papaverine, Halidor) ½-1 tablet three times a day, or cholinolytic-aspasmodics (Platifylline, Metacin, Buscopan) 1/3-1 tablet three times a day before meals is indicated.

From the group of non-absorbable antacids most often prescribe Fosfalyugel, Gastal, Maalox, Rutacid - up to 4 times a day, for up to one month.

Use Painkillers for gastritis during pregnancy

Gastritis is a disease that can affect almost anyone, including a pregnant woman. The difficulty lies in the fact that painkillers, which are usually used by doctors to treat the disease, are not always and not all allowed during pregnancy. For example, the chronic form of gastritis rarely begin to treat in this period: usually wait until the birth of the child, or even the end of breastfeeding. After all, to obtain a lasting effect it is necessary to neutralize the bacterium Helicobacter, and this requires prolonged antibiotic therapy, contraindicated during pregnancy.

At the stage of exacerbation of gastritis, a pregnant woman is prescribed treatment with only some safe drugs:

• Gastropharm (a natural preparation based on lactobacilli and products of their vital activity).
• No-shpa, Drotaverine (in minimal doses and under the supervision of a doctor, as in the second trimester of pregnancy, the drug can cause cervical shortening, CPI and the threat of premature labor).
• Maalox (means based on aluminum and magnesium hydroxides).

If the level of acid in the stomach is insufficient, you can take medications Panzinorm, Riboxin, Pepsidine. Self-medication is strictly forbidden: in pregnancy, all prescriptions must come from the doctor.

Contraindications

You should not take painkillers without a doctor's prescription if the patient has these signs:

• sharp increasing abdominal pain;
• a rise in temperature;
• nausea and vomiting without relief, vomiting blood;
• bloody diarrhea, bloody stools;
• tension in the muscles of the anterior abdominal wall;
• sharp pain when pressing on the area of the anterior abdominal wall, pain on percussion (Mendel's symptom);
• sharp pain in the abdomen against the background of rapid removal of palpating (pressing) brush from the area of the anterior abdominal wall (Shchetkin-Blumberg symptom).

If these symptoms occur, you should immediately consult a doctor. Do not take any medications, including painkillers, for such conditions on your own.

Side effects Painkillers for gastritis

Common side effects of painkillers for gastritis are symptoms such as:

• Difficulty with defecation, prolonged absence of defecation, constipation;
• dyspepsia, nausea, vomiting;
• the appearance of an unpleasant taste in the mouth, unusual changes in taste;
• allergic reactions, hypersensitivity.

On the background of prolonged use of certain medicines - for example, antacids - against the background of renal failure, mood swings and changes in mental activity are noted. Prolonged treatment with high doses may lead to drug overdose and osteomalacia.

Overdose

A single overdose, as a rule, is not accompanied by pronounced negative manifestations. It is possible to develop constipation, increased gas formation, dyspepsia.

Prolonged use of large amounts of analgesics - e.g. Antacids - can lead to nephrocalcinosis, severe defecation difficulties, constant fatigue, and hypermagnesemia. It is possible to develop metabolic alkalosis, a condition that is manifested by the following signs:

• mood swings, sudden changes in mental activity;
• paresthesias, myalgias;
• irritability, frequent unexplained fatigue;
• slower respiratory rate;
• taste disturbances.

If you suspect an overdose of painkillers for gastritis, it is necessary to provide a large intake of fluid into the body. If possible, induce vomiting, take sorbents (activated charcoal, Sorbex, etc.).

Interactions with other drugs

How do pain relievers for gastritis interact with other medications?

Sorbents and antacids can absorb other medicines, thus reducing their absorption. To avoid this, they should be taken 1-2 hours apart.

Antacids reduce the absorption of Reserpine, cardiac glycosides, iron and lithium preparations, phenothiazines, _{histamine-H2-receptor} blockers, quinidine, tetracyclines, Ketoconazole, Ciprofloxacin.

Against the background of taking capsules or tablets with intestinal soluble coating, excessive acidity of gastric juice may cause accelerated destruction of this coating. As a consequence, there is additional irritation of the walls of the stomach and 12-intestine.

Benzocaine preparations are not taken at the same time as sulfonamide preparations.

Storage conditions

Most analgesic medicines are afraid of light: to ensure that they do not lose their effect, they should be placed in a darkened place, hidden from direct sunlight. The best option is a special cabinet with an opaque door.

The next condition is dryness. Any tablets, capsules and sachets can actively absorb moisture and, as a consequence, deteriorate. It is because of this that it is not recommended to store pain medications in the shower, bathroom and even in the kitchen (especially in close proximity to the sink and stove). The living room, pantry are excellent rooms where there will certainly not be excess moisture.

The refrigerator is not the best place to store medicines unless the instructions include the phrase "keep in a cool place". Even if the medicine requires such cool conditions, it should not be placed near the freezer and should always be wrapped in a cellophane bag.

Whichever place you choose to store your painkillers, the medicine should always be in its original original factory packaging. The name of the drug, as well as its date of issue and expiration date, should be clearly legible, and all tablets (capsules, ampoules) should be well packed. It is not necessary to pile the drugs in one bottle or box, cut off the used part of the blister plates, etc. The medicine should be kept in its own box together with the instructions.

One last important condition: children and mentally ill people should not get to your medicine cabinet. Medicines can be dangerous for them.

Shelf life

There is a clearly defined shelf life for all medicines, which is always indicated on the original packaging. This period is valid if the medicines are stored under the required conditions. Otherwise, the drug may spoil and lose its therapeutic properties much earlier than the specified date.

Before taking this or that analgesic for gastritis, you should always pay attention to the expiration date of the drug: expired medication is better not to take, so as not to harm your own health.

Analogues of painkillers for gastritis

Painkillers for gastritis can be replaced by means of folk medicine, which are no worse cope even with severe pain. We are talking about such popular and effective remedies:

• Flaxseed: one teaspoon of seeds pour 100 ml of boiling water, cool and drink before meals.
• Raw potato juice is taken half an hour before meals, in an amount of 100 ml.
• Infusion of chamomile is brewed in the proportion of 200 ml of boiling water per 1 tbsp. Of raw materials. Drink warm three times a day, between meals.
• Sea buckthorn oil is taken 1 tsp. Up to three times a day daily for a month.

Most folk remedies have a long-lasting and persistent effect, but they should be taken for a long time - at least 3-4 weeks. If the pain does not go away, it is necessary to visit a doctor and undergo a course of medical treatment.

Testimonials

Consumption of low-quality foods and drinks, alcohol abuse, frequent and uncontrolled use of medications, smoking, regular stress, neurosis - all these factors can provoke the development of acute gastritis. Such a disease is accompanied by severe pain, apathy, deterioration of appetite. The workability of a person practically goes to "no". To avoid this, it is very important to know what will help to correct the situation and relieve the patient from suffering.

According to numerous reviews, even an ordinary enveloping agent often quickly and qualitatively eliminates the pain of gastritis. For example, such drugs are Almagel A, Fosfalyugel, Maalox and so on. Analogues can be ordinary flaxseed, which has a similar therapeutic effect. If you conduct a comprehensive treatment, combining such drugs with other drugs that restore the gastric mucosa, you can successfully not only relieve pain, but also stop the development of the inflammatory process.

Nevertheless, thoughtlessly take medicines can not be taken: even conventional painkillers for gastritis have a whole list of contraindications, and also require simultaneous careful observance of the diet. Therefore, before taking a tablet or suspension, it is necessary to consult a doctor.