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Optirei
Last reviewed: 23.04.2024
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Optiray is a substance used in diagnostic procedures - to perform a contrast X-ray. After being introduced into the vascular region, the substance is secreted under x-rays, due to which it is possible to study the state of the cardiovascular system.
After intravascular use of drugs, the blood flow, which contains a contrasting element, becomes opaque to x-rays. As a result, the circulatory system of internal organs acquires radiographic visualization (until the level of the contrast component is reduced).
Indications Optiraea
It is used for angiographic examination of vessels located in different areas of the body (peripheral as well as cerebral and peritoneal), and in addition, for intravenous urography.
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Release form
The release of the component is realized in the form of a solution, inside the flasks with a capacity of 0.1 l - 10 pieces inside the pack.
Pharmacokinetics
Less than 2% of the drug is synthesized with intraplasma protein. The Cmax index of the element is recorded inside the blood after the 1st hour has passed since the moment of use. Optiray is able to overcome the BBB and excreted with mother's milk.
The term half-life after the introduction of a portion of 0.15 liters is approximately 2 hours.
Dosing and administration
The drug is used intravenously or intraarterially. It can be administered by jet or through an IV. The volume of the element used is determined by the age and weight of the patient, as well as the hemodynamic picture and the state of the vascular area under study. The patient cannot be eaten for 2 hours before the diagnosis.
Dosages required for examination of different vascular areas:
- the vertebral or carotid artery is injected in 2-12 ml of the substance;
- total iliac or femoral - in the range of 10-50 ml;
- brachial or subclavian - within 15-30 ml;
- inferior mesenteric artery or circulatory system of the kidneys - 6-15 ml;
- aortic bifurcation - 20-90 ml.
In the case of venography, 30-80 ml of the drug are used, and for intravenous urography, 65-80 ml.
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Use Optiraea during pregnancy
Pregnant women can not carry out the procedure of hysterosalpingography.
Contraindications
Among the contraindications:
- strong sensitivity associated with medication;
- thyrotoxicosis;
- kidney or liver failure;
- risk of developing epilepsy attacks;
- breastfeeding period;
- active inflammation in the pancreas area (in the case of cholangiopancreatography);
- inflammation affecting the organs in the pelvic area;
- plasmacytoma having a generalized character;
- severe pathologies associated with cardiovascular disease.
Side effects Optiraea
Adverse symptoms usually occur immediately after the use of the drug. Among these are: loss of consciousness, pain, burning and fever, a decrease in heart rate, visual disturbance, a decrease in blood pressure, heart rhythm disorder and IHD. In addition, hemiparesis, nausea, pruritus, kidney work disorder, encephalopathy, cyanoderma, swelling or rashes of an allergic nature, as well as discrepancy between BCC and the volume of the vascular bed develops.
Local signs include tissue necrosis and vascular spasm.
Manifestations of allergies can develop after a few days from the moment of the procedure.
Overdose
Drug intoxication can lead to respiratory failure, renal failure or cardiovascular function.
Interactions with other drugs
You can not mix Optiray with other medicines. Analgesic drugs and psychotropic drugs increase the risk of developing negative symptoms.
Hypoglycemic agents increase the likelihood of kidney failure, which is why they need to be stopped 2 days before the examination.
The use of β-adrenomimetics increases the risk of allergy.
Leukocyte-type cytokines are capable of provoking the development of lesions, fever, joint pain and itching.
Storage conditions
The optics should be kept in a closed place from the penetration of sunlight. Temperature values - maximum 30 ° C.
Shelf life
Optiray allowed to apply within the 36-month term since the sale of drugs (a substance that has not been subjected to X-ray exposure or freezing). The shelf life of substances that are stored inside the heater, where air enters (37 ° C) is 1 month.
Application for children
In pediatrics, Optiray is not used.
Analogs
An analogue of the drug is the substance Yoversol.
Attention!
To simplify the perception of information, this instruction for use of the drug "Optirei" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.