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Health

Ocacin

, medical expert
Last reviewed: 03.07.2025
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Ocacin is an antimicrobial ophthalmologic agent of the first-generation fluoroquinolone antibiotic group. ATX code S01AE04, J01MA07. International name - Lomefloxacin; other trade names: Lomecin, Lomeflox, Lofox, etc.

Indications Ocacin

Ocacin eye drops are used in the treatment of such ophthalmological diseases as acute and chronic bacterial inflammation of the mucous membrane of the eye (conjunctivitis), inflammation of the eyelids (blepharitis), inflammation of the cornea (keratitis), inflammation of the lacrimal sac (dacryocystitis) and other eye infections.

Release form

Eye drops 0.3% in 5 ml bottles.

Pharmacodynamics

Ocacin exhibits bactericidal activity against many gram-negative and some gram-positive aerobic microorganisms (Staphylococcus saprophyticus, Staphylococcus aureus and Staphylococcus epidermidis), as well as Chlamydia trachomatis. The drug is ineffective against Streptococcus spp., Streptococcus pneumoniae, Pseudomonas cepacia, Ureaplasma urealyticum, Mycoplasma hominis and anaerobic bacteria.

The active substance of Ocacin - lomefloxacin hydrochloride - blocks the action of bacterial enzymes (topoisomerase II and IV), thereby stopping the process of transcription and replication of their DNA, protein synthesis and other biochemical processes that ensure the viability of bacterial cells.

Pharmacokinetics

Data on the absorption of Ocacin eye drops after intraconjunctival application are not provided.

Dosing and administration

Ocacin eye drops should be instilled into the lower conjunctival sac: at the initial stage of treatment - one drop every 5 minutes for 25 minutes or one drop per hour for 8 hours. In the following days, one drop should be instilled into each eye 2-3 times a day. The duration of the course of treatment is 7-9 days.

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Use Ocacin during pregnancy

Contraindicated

Contraindications

Contraindications to the use of the drug are hypersensitivity to fluoroquinolones, soft contact lenses, childhood (under 15 years).

Side effects Ocacin

Side effects of Ocacin manifest themselves in the form of a quickly passing slight burning sensation in the eyes after instillation. Also, after local application, allergic reactions to ultraviolet radiation (shortness of breath, urticaria, erythema, itching of the skin) are not excluded, which often occur with the systemic use of the tablet form of lomefloxacin. Therefore, during the period of use of this drug, it is better to hide from direct sunlight.

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Overdose

Topical use of lomefloxacin hydrochloride has not been described.

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Interactions with other drugs

To avoid reducing the effectiveness of Okacin, do not use zinc-containing preparations for 15 minutes before and after its use.

Other bacteriostatic ophthalmic antibiotics should not be used simultaneously with Ocacin.

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Storage conditions

Store in a dark place out of reach of children (list B), at room temperature.

Shelf life

The drug in an unopened bottle – 3 years.

Attention!

To simplify the perception of information, this instruction for use of the drug "Ocacin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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