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Neyromidin
Last reviewed: 23.04.2024
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Indications Neuromidine
It is used in the following conditions:
- poly-and mononeuropathy with different degrees of intensity;
- multiple sclerosis ;
- paralysis or pathology affecting the central nervous system;
- movement disorders associated with organic lesions or injuries;
- tablets can be administered with a weak intestinal tone.
Release form
The component is released in tablets (10 pieces inside a pack) or in the form of a liquid, inside ampoules with a capacity of 1 ml.
Pharmacodynamics
Neuromidine blocks the activity of Ca channels and decreases potassium indices, respectively, increasing the calcium values inside nerve cells. At the same time, the drug prevents the effect of cholinesterase in the area of neuromuscular fibers. These processes can increase the number of conductors (adrenaline with serotonin, histamine and oxytocin) inside the cells. At the same time, the activity of postsynaptic cells increases, and the conductors are able to penetrate the semi-impermeable cell wall. The drug stabilizes the transmission of neural impulses within muscle tissue.
In a patient who uses Neuromidine, smooth muscle tone is increased, memorization processes are simplified, and synaptic connections inside neuronal fibers are restored.
Pharmacokinetics
The applied preparation is synthesized with blood protein, passing at high speed into the target organs. The drug undergoes intrahepatic exchange. Blood Cmax values are noted after half an hour.
Excretion is carried out by the excretory system - with the participation of the gastrointestinal tract and kidneys (with urine).
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Dosing and administration
The drug can be used in tablets or administered parenterally through injections (taking into account the type of pathology and the degree of its intensity). For the day, you can use no more than 200 mg of the substance.
In the case of mono- or polyneuropathy, the drug is administered intramuscularly or intravenously, in a portion of 30 mg (for 2 administrations), over a 10-15-day cycle. Then it is taken orally - 3 tablets per day (1 tablet 3 times) in the period of 1-2 months.
For disorders of the activity of movements associated with various organic lesions or injuries, the substance is applied through a / m injection (15 ml), 2 times a day for a period of 15 days.
Combination therapy for multiple sclerosis includes taking the 1st tablet of a substance 4 times a day for 2 months. This course is required to be repeated several times a year.
In case of intestinal atony, 20 mg of drug is used 3 times a day during a 1-2 week cycle.
In case of various pathologies affecting the central nervous system, 5-15 mg of the drug are administered 2 times a day, for a period of 10-15 days, or they take 1 tablet 3 times a day for 3-6 months.
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Contraindications
The main contraindications for tablets:
- bradycardia or arrhythmia;
- epilepsy;
- stomach ulcers;
- asthma or allergies associated with individual elements of the drug.
Overdose
Drug poisoning causes vomiting, bronchial spasms, nausea, a decrease in blood pressure, loss of appetite, a feeling of fear, an upset heart function (bradycardia or tachycardia), jaundice, cramps, and a feeling of general weakness.
Symptomatic measures are carried out, and cyclodol or atropine is introduced.
Interactions with other drugs
Neuromidine potentiates the overwhelming effect on the central nervous system, if it is administered together with sedative components.
Negative manifestations of drugs are potentiated when combined with other anticholinesterase drugs or ethyl alcohol.
The drug reduces the therapeutic activity of anesthetics.
The drug can be combined with nootropic drugs.
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Storage conditions
Neuromidine must be kept in a dark place that is closed to children. The temperature values are within 25 ° C.
Shelf life
Neuromidine tablets can be used within a 1.5-year period from the time the substance is manufactured. The shelf life of the injection fluid is 1 year.
Application for children
It is forbidden to use the drug in pediatrics (children under the age of 14).
Analogs
Analogues of the medication are drugs Amiridin 20 mg with Axamon and Hyprigrix, and in addition Prozerin and Kalimin 60 N.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Neyromidin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.