Nasobek

Nasobek is a medicine with anti-allergic and anti-inflammatory properties, and in addition, it removes swelling.

Indications Nasobeca

It is used to eliminate different types of rhinitis (including allergic or vasomotor).

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Release form

It is released in the form of a suspension for spray, in bottles with a volume of 100, 180 or 200 doses.

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Pharmacodynamics

The active component of the spray is an artificial GCS. It stimulates the production of the element lipomodulin (a substance that slows down the activity of the enzyme phospholipase A), and in addition, it interferes with the process of binding arachidonic acid. As a result, inflammatory exudation is reduced, as well as the binding of lymphokines, and the process of accumulation of neutrophils at the vascular walls is inhibited.

Suppression of granulation and infiltration processes also occurs – this is facilitated by the fact that beclomethasone can suppress the movement of macrophages. There is a decrease in swelling, a decrease in the amount of mucus produced, and an improvement in mucociliary movement.

The medicine is well tolerated, even in case of prolonged use. Symptoms of the disease subside after 2-3 days from the beginning of the course.

Pharmacokinetics

After administration through inhalation, the substance is poorly absorbed into the body. The small portion of the active component that enters the gastrointestinal tract is destroyed in the liver.

Part of the drug is excreted after 15 hours, with about 90% of the component undergoing protein synthesis within the plasma. Excretion occurs with feces, and the remainder of the substance is excreted by the kidneys.

Dosing and administration

The spray is administered intranasally.

Starting from the age of 12, the medicine is prescribed in a dosage of 1-2 injections into each nostril, twice a day.

Children aged 6-12 years are allowed to use no more than 400 mg per day. They are usually prescribed 1 spray in each nostril twice a day.

The course must be continued until an improvement in the patient’s condition is noted.

Before using the medicine for the first time (or when using it after a long pause), shake the bottle with the spray. Then press it into the air several times until a white cloud appears. After that, exhale and pinch one nostril with your finger, while simultaneously spraying the spray into the other. Spraying is done on an inhale, after which you need to exhale through your mouth. Then repeat this procedure with the other nostril.

After completing the procedure, you need to wipe the sprayer using a handkerchief or damp cloth.

In addition, it is recommended to clean the applicator at least once a week. You need to remove the nozzle, rinse it with warm water, then dry it and put it back on.

Use Nasobeca during pregnancy

Nasobek is prohibited to use in the 1st trimester. It is prescribed with caution in the 2nd and 3rd trimesters.

Contraindications

Main contraindications:

• the presence of hypersensitivity to any of the components of the drug;
• hemorrhagic form of diathesis;
• tendency to nosebleeds;
• an infection of viral or fungal origin;
• tuberculosis in the respiratory system;
• children under 6 years of age.

Caution is necessary in the following cases:

• with hypothyroidism or glaucoma;
• during breastfeeding;
• if there are ulcers or cuts in the area of the nasal septum;
• in case of liver diseases or amebiasis;
• in case of recent myocardial infarction;
• in the period after nasal surgery or in case of damage to the nose.

Side effects Nasobeca

Occasionally, the following side effects may occur as a result of using the spray:

• skin rash, urticaria, and angioedema;
• development of candidiasis;
• a feeling of drowsiness or weakness, as well as headaches and disturbances of taste or olfactory receptors;
• the appearance of bleeding, dryness in the nasal and oral mucosa, itching with burning in the nose, as well as coughing and rhinorrhea.

The following problems are observed occasionally:

• perforation of the nasal septum, as well as the appearance of ulcers in the nasal mucosa;
• thinning of bone structures and decreased growth rates in children;
• weakening of vision, glaucoma or conjunctivitis.

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Overdose

As a result of prolonged use in high doses, the patient may develop hypercorticism. To eliminate the disorder, it will be necessary to discontinue the drug - this should be done by gradually reducing the dosage.

Interactions with other drugs

As a result of the combination with phenytoin, as well as ephedrine, rifampicin, phenobarbital, and glutethimide, a weakening of the medicinal effect of Nasobek is observed.

When combined with antithrombotic drugs, adrenergic agents, orally administered antidiabetic agents, digitalis drugs, and indapamide, the likelihood of side effects on both sides increases.

The drug reduces the effectiveness of isoniazid.

When combined with systemic GCS and anti-asthmatic drugs, their properties are potentiated.

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Storage conditions

Nasobek should be kept in a place inaccessible to children. The temperature should be within 10-25°C.

Special instructions

Reviews

Nasobek receives mostly positive reviews. It is often used to combat allergic symptoms, and in addition to this, to eliminate the signs of sinusitis that cannot be eliminated with vasoconstrictor agents. When combined with antibiotics, the drug helps to cure sinusitis.

Some patients who have become dependent on vasoconstrictor drugs try to overcome it by using Nasobek.

The advantages also include the rarity of side effects, as well as the convenient spray form and pleasant smell of the medicine. In addition, patients also note the fairly low price for the medicine.

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Shelf life

Nasobek can be used for 4 years from the date of manufacture of the drug. An opened bottle of spray can be used for a maximum of 3 months.