Nandrolone is a hormone, an artificial testosterone derivative. Its main active ingredient is nandrolone decanoate.
The drug is synthesized with special protein conductors located on the cell surface of target organs. As a result, the conductor-nandrolone complex is formed, which helps to move the latter through the cell membrane into the hyaloplasm, and then the substance from there penetrates the membrane of the nucleus into its cells, provoking the activation of the gene regulating the process.
The androgenic effect of drugs occurs by stimulating the binding of nucleic acids (such as DNA together with RNA) and structural proteins, and in addition, by enhancing the respiratory activity of tissues and the oxidative process of phosphorylation inside the skeletal muscles (against this background, cumulation of macroerges - such as ATP and phosphocreatine). Together with this medicine increases the volume of muscle mass and reduces the amount of fat deposits. It also activates the process of growing male genital organs together with the formation of secondary sexual characteristics (male type). The active component helps to stop skeletal growth and stimulates the process of bone calcification in the area of growth zones. Also, the drug accelerates the excretory activity of androgen-dependent glands - male genital (stimulates spermatogenesis), as well as sebaceous. High doses of drugs suppress interstitial cells, as well as lower the binding of internal sex hormones (by inhibiting the pituitary FSH production processes, as well as LH (negative feedback)).
Anabolic effects occur through the stimulation of healing processes in the epithelium (both glandular and integumentary), and in addition to muscle and bone tissue - activates the process of protein synthesis with structural cellular elements. The drug enhances the degree of absorption of amino acids from the small intestine (if the patient adheres to a protein diet), thereby creating a positive ratio of nitrogen values. Promotes the production of erythropoietin, as well as anabolic bone marrow processes (this property, in the case of a combination with iron drugs, causes an anti-anemic effect).
It interferes with the process of binding plasma factors (dependent on vitamin K group) of blood coagulation (types 2, 7, and also 9 and 10) occurring in the liver. In addition, it changes the nature of the lipid profile (increases the value of LDL, while reducing the level of HDL), and also increases the renal reabsorption of water with sodium, leading to the formation of peripheral edemas.