The drug should be administered intravenously (do it slowly: 2-3 minutes), as well as by subcutaneous or intramuscular route.
In case of drug intoxication, the initial dosage is 0.4 mg. If this is necessary, it is required to enter this dose repeatedly, keeping the intervals of 3-5 minutes, until spontaneous breathing is restored, and the patient does not regain consciousness. The maximum dose is 10 mg. The initial infant dosage is 0.005-0.01 mg / kg.
To accelerate the withdrawal from anesthesia used in surgical operations, an injection of 0.1-0.2 mg (about 1.5-3 μg / kg) is necessary at intervals of 2-3 minutes. Follow the procedure until the required pulmonary ventilation appears, and the patient wakes up. The pediatric dose is intravenous, 0.001-0.002 mg / kg, and if this does not work, repeat doses of up to 0.1 mg / kg at intervals of 2 minutes (until consciousness recovers and spontaneous breathing begins). If you can not do IV administration, you need to inject subcutaneously or intramuscularly. For newborns, the initial dosage is 0.01 mg / kg.
In the case of oppression of the respiratory process in newborns, which developed due to the introduction of opiate painkillers during childbirth, an injection of 0.1 mg / kg of the drug (by way of iv, in / m or s / k) is required. In the future, it is allowed to inject LS as an intramuscular injection in the amount of 0.2 mg (or 0.06 mg / kg).
To diagnose the patient's opioid addiction, you need to inject 0.8 mg of the drug intravenously.