The drug can be administered both in / m and / in the way. The size of the dose is selected separately for each patient, taking into account the tolerability of the drug, and in addition to this intensity of pain and the characteristics of the patient's body.
The adult dose is often 0.15-0.3 mg / kg. In this case, the interval between the procedures should be at least 4 hours. The maximum of a single recommended dose is 0.3 mg / kg. For a day it is allowed to inject no more than 2.4 mg / kg of a drug solution. It is forbidden to use the medicine for more than 3 days in a row.
In the case of myocardial infarction, 20 mg of nalbuphine hydrochloride is usually administered (one-time IV administration). The rate of solution should be slow. If there is a need, it is allowed to increase a single dose to 30 mg. If the positive result (pain relief) is absent in half an hour after drug administration, it is required to repeat the procedure - to enter 20 mg of Nalbuphin.
With the preoperative preparation of the patient, usually 100-200 μg / kg of the drug is administered.
If an anesthesia is used to inject a person into anesthesia, nalbuphin is used at a rate of 0.3-1 mg / kg, and then, in order to maintain anesthesia, a drug of 250-500 μg / kg should be injected every subsequent half-hour.
It is also necessary to take into account that people suffering from opiate addiction have a risk of developing withdrawal syndrome when using Nalbuphine (morphine can stop them). Persons receiving codeine or morphine and other opioid analgesic drugs before starting the use of nalbuphine are required to prescribe the latter at a rate of 25% of the usual dose.
The solution must be administered by an experienced doctor. At the same time he must have at hand all the means necessary to eliminate a possible overdose (among them naloxone, as well as the availability of equipment for performing artificial pulmonary ventilation, as well as intubation).