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Maxicold
Last reviewed: 03.07.2025
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Maxikold is a combination drug used to eliminate pathologies of an infectious or inflammatory nature, accompanied by pain inside the joints and muscles, as well as elevated temperature.
Indications Maxicold
It is indicated for inflammatory and infectious diseases (such as influenza or acute respiratory viral infections), during which there are chills, headaches, fever, nasal congestion, pain inside the muscles and joints, as well as in the sinuses and throat.
Release form
It is available in powder form for oral solution. Powder sachets have a volume of 5 g. One package contains 5 or 10 sachets.
Maxikold with orange flavor. The medicine is available in the form of a powder with an orange flavor, a specific smell and a yellow tint. The mixture may contain white crystals, as well as easily soluble lumps. As a result of dissolution in water, an opalescent solution is formed, which has an orange smell and a light yellow tint.
Maxicold with lemon flavor. Powder with lemon flavor, specific smell and yellow tint. The powder may contain white crystals, as well as quickly dissolving lumps. As a result of dissolution in liquid, a light yellow opalescent solution is formed, having a lemon smell.
Maxicold with raspberry flavor. Raspberry powder has a shade that fluctuates from light pink to dark (with small inclusions of red). The presence of white crystals in the mixture together with small lumps is allowed. After its dissolution in water, a special opalescent solution is formed, smelling of raspberries and having a pink color.
Maxikold Rhino is used to eliminate the manifestations of the disease in acute forms of respiratory diseases.
Pharmacodynamics
The properties of Maxikold are determined by the active substances contained in the drug:
- Phenylephrine has a vasoconstrictor effect, helping to facilitate the process of breathing through the nose, as well as clearing the paranasal sinuses and nasal passages;
- paracetamol has analgesic and antipyretic properties. It acts by reducing muscle and headache pain, as well as fever symptoms, and in addition, it alleviates pain in the throat;
- Vitamin C enhances the body's immune response to infections and also helps to activate carbohydrate metabolism and the development of oxidation-reduction processes.
Reviews indicate that the drug is effective when used in recommended dosages for a period of 3-5 days.
Dosing and administration
The powder with the medicine (1 packet) should be poured into a mug, then hot water should be added and stirred until the powder is completely dissolved. Then this liquid should be drunk (hot).
For adults, the dose is 1 packet every 4-6 hours. More than 4 packets per day (24 hours) cannot be used. It is also prohibited to use the drug more often than every 4 hours.
For children over 12 years old, the dose is 1 packet every 6 hours. No more than 3 packets can be consumed in a 24-hour period.
It is necessary to warn the patient that the medicine cannot be used as an analgesic for a period longer than 5 days, and as an antipyretic - no more than 3 days. A longer course can only be prescribed by a doctor on an individual basis.
If, after using the medicine during the specified period, the symptoms of the disease persist, you should consult a doctor.
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Use Maxicold during pregnancy
The medicine should be used with caution during pregnancy or lactation.
Contraindications
Among the contraindications:
- severe form of disorders in the functioning of the kidneys or liver;
- presence of thyrotoxicosis;
- cardiac pathologies (for example, severe aortic stenosis);
- presence of tachyarrhythmias;
- acute myocardial infarction;
- high blood pressure;
- combined use with MAO inhibitors, β-blockers and tricyclics (also in the time period of up to 2 weeks after stopping their use);
- combination with other drugs containing paracetamol, or drugs that relieve symptoms of flu, colds and nasal congestion;
- prostate adenoma;
- closed-angle glaucoma;
- age less than 12 years;
- intolerance to the components of the drug.
Caution is required in cases of genetic G6PD deficiency, as well as liver or kidney failure, benign hyperbilirubinemia, diabetes mellitus, and problems with glucose absorption (hereditary). It should also be prescribed with caution to the elderly.
Side effects Maxicold
Paracetamol can cause the following adverse reactions: allergic reactions (angioedema, skin rashes, urticaria), and occasionally agranulocytosis or thrombocyto- and leukopenia may develop.
Side effects due to the properties of phenylephrine: headaches with nausea, and also a slight increase in blood pressure; occasionally, palpitations occur (these phenomena disappear after discontinuation of the drug).
As a result of prolonged use in high doses, the likelihood of developing functional disorders of the kidneys or liver increases.
Overdose
Overdose usually occurs due to the effects of paracetamol. Its manifestations include the development of anorexia, hepatonecrosis and pale skin, vomiting with nausea, increased PT, and increased liver transaminase activity.
To remove the symptoms of the disorder, it is necessary to perform gastric lavage and give the patient activated carbon. Symptomatic treatment is also used. Paracetamol intoxication can be removed by using a specific antidote - the substance N-acetylcysteine.
Interactions with other drugs
The drug increases the effects of sedatives, ethyl alcohol and MAO inhibitors.
Antiparkinsonian drugs, antidepressants, antipsychotics, and phenothiazine derivatives increase the likelihood of developing dry mouth, constipation, and urinary retention.
GCS increases the risk of glaucoma, and halothane increases the risk of ventricular arrhythmia. Paracetamol weakens the effect of diuretics, and phenylephrine weakens the antihypertensive properties of guanethidine. At the same time, guanethidine increases the effect of alpha-adrenergic stimulants, and tricyclics enhance the sympathomimetic properties of phenylephrine.
The possibility of a hepatotoxic effect increases in case of combination with diphenin, rifampicin, as well as carbamazepine, barbiturates, zidovudine and other inducers of microsomal liver enzymes.
Storage conditions
The medicine should be kept in a place inaccessible to children, protected from moisture. The temperature level should not exceed 25ºС.
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Shelf life
Maxikold is permitted to be used for a period of 2 years from the date of release of the drug.
Attention!
To simplify the perception of information, this instruction for use of the drug "Maxicold" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.