Lazorine

Lazorin is widely used to prevent problems associated with swelling of the nasal mucosa. Simply put, use it in the period of worsening allergies and colds. 

Indications Lazorine

The main indications for the use of Lazorin are the complete elimination of inflammation of the nasal mucosa. Usually, this phenomenon occurs during the course of rhinitis. Acute manifestation of the disease and other infectious and inflammatory processes in the organs of hearing and breathing lead to puffiness. All this brings a lot of discomfort to a person. The effective remedy of Lazorin will help to get rid of the problem. It does not carry danger, therefore it is widely used in medicine.

It is actively used for sinusitis, eustachitis, otitis. It makes it easier to move away from the secret. This tool is difficult to call strong in its kind, because it does not include antibiotics in its composition. Therefore, it can be safely applied, but after consulting a doctor. The drug is used both alone and in complex therapy to eliminate inflammatory diseases. Much depends on the patient's condition. Fight with acute rhinitis medication "alone" can not. To find an effective treatment in this case will help a specialist. 

Release form

The form of release - a spray for a nose in a dosage of 1,18 mg / ml. It is found in a can of glass, with a special dispensing valve, 10 ml. In 1 ml of the drug contains many useful components. So, this is 1,265 mg of tramazoline hydrochloride monohydrate. This dosage completely corresponds to 1.18 mg of tramazolin hydrochloride.
Additional substances include: sodium hydroxide, citric acid, povidone. Active effect: benzalkonium chloride, magnesium sulfate heptahydrate, hydroxypropylmethylcellulose, calcium chloride dihydrate. For maximum effect, sodium chloride, sodium bicarbonate, menthol, eucalyptus, camphor, purified water were included in the composition.

Thanks to its rich composition, the effect of using the drug is achieved quickly. The main thing is to go through the treatment properly and not deviate from the prescribed scheme. In this case, a positive result will not be long in coming. There is no other form. Lazorin is supplied exclusively in the form of a spray. Tablets, capsules and drops do not exist. Therefore, going for a tool, it is worth knowing in what form it is sold. 

Pharmacodynamics

Pharmacodynamics Lazorin - the active active ingredient is tramazolin. Its main group is α-sympathomimetics. Component has a pronounced vasoconstrictive effect. It perfectly removes the swelling of the nasal mucosa. This allows for breathing. When Lazorin is digested in the nasal passages, the effect of vasoconstriction is noted literally in 5 minutes. A person feels a great relief for 10 hours. Therefore, it is not necessary to use the medicine often. This greatly simplifies the situation, especially if a person is constantly on the move.

As such, pharmacokinetic studies on humans have not been conducted. In the laboratory, about 50-80% of Lazorin was absorbed. Metabolites tramazolin and the main components of the drug are perfectly distributed to the necessary organs and tissues. An increased dose of medication was recorded in the liver. The period of partial excretion is 5-7 hours. As for elimination, it is carried out by the kidneys. After using the drug, in the urine there were three main metabolite components found in its composition. 

Pharmacokinetics

Pharmacokinetics Lazorin - the effect of the first passage is through the liver. The main component of the drug is tramazolin. It actively narrows the vessels, significantly reduces the swelling of the nasal mucosa. All this greatly improves nasal breathing. The main effect is visible after 5 minutes. Breathing becomes much easier. All this remains for 8-10 hours. This will, does not carry a tool with him constantly.

No special pharmacokinetic studies were conducted. During the conducted studies, it was concluded that 50-80% completely absorbed from the body. Metabolites of tramazolin and the main active ingredient are gradually and evenly distributed over all affected tissues. An increased concentration is observed in the liver. The active component is completely eliminated by the kidneys. If we talk about the half-life, it is 5-7 days. In urine, after consumption, there are three main components. 

Dosing and administration

The way of application and dose in some kind are individual. So, children from 6 years and adults need to take the drug for one dose up to 4 applications per day. Thus, the maximum effect is achieved. It is highly recommended not to use the medication for more than one week.

Before each use of Lazorin, the safety cap must be removed from the can. Before use, the nasal cavity should be thoroughly cleaned of excess mucus. Otherwise, the medicine can not reach its destination. Then, the tip is inserted into each nasal turn in turn and the pressure is applied to the dispenser. One injection is sufficient, and it should be deeply inhaled. After use, the tip should be thoroughly rinsed. It should not remain slime. Then the can is tightly closed and placed in a place of its storage.

During the use of the drug by children, it is worthwhile to monitor this process. After all, they can harm your own body. Naturally, this is not permissible. As for pregnant women, the dosage in this case is of an individual nature and is agreed upon separately with the attending physician. 

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Use Lazorine during pregnancy

The use of lazorine during pregnancy is highly not recommended. The first trimester is especially dangerous. During this period, the use of any means is fraught with serious consequences. There was no pathological effect on the mother or child's organism during the gestation period. But, despite this, Lazorin should be excluded from the application for the first time for months. In the second and third trimester, it is recommended to stipulate the possibility of using the product with a doctor. No data are available regarding the use of the medication during breastfeeding. Therefore, it is not recommended to combine these two processes.

The agent is not able to penetrate deep into the body and thereby harm it. But, there are different situations. How does Lazorin affect the fetus and is it capable of causing harm, it is difficult to say. Therefore, the risk persists. It is better not to resort to treatment on your own. As mentioned above, it is especially dangerous to do this for the first time in months of pregnancy. In the rest all is spent under supervision of the expert. 

Contraindications

Contraindications to the use of Lazorin are available, and they are mainly associated with increased hypersensitivity to the main components of the drug. Otherwise, the risk of developing a serious allergic reaction remains high. Despite the high effectiveness of eliminating rhinitis, it is undesirable to use the drug in its atrophic form.

With closed glaucoma, you should avoid treatment with this medication. Despite its safety, the facility is not used by children under the age of six. There is a chance of damage to the nasal mucosa. Lazorin is highly not recommended to be used after surgical interventions that have been carried out by penetrating into the nasal cavity.

Any medication is used individually. Therefore, to apply Lazorin without the knowledge of a specialist is not worth it. There is a risk of getting an allergic reaction of any complexity. Increased risk is observed in children, this fact should be taken into account. 

Side effects Lazorine

Side effects of Lazorin are manifested in different ways. Basically it is a headache, sneezing. This is because the person has a mild allergic reaction to the components of the drug. This is quite normal, and no danger. But if there is drowsiness, accompanied by dizziness and impaired taste, it is worth stopping the medication. This is fraught with serious consequences.

Sometimes there is tachycardia. Not excluded a significant jump in blood pressure. The heart rhythm can also change. It is especially dangerous for people who have heart problems. It is not excluded the appearance of hallucinations. Sometimes there is dryness and severe burning of the mucous membrane, sneezing, nosebleeds. Nausea is possible. This is due to the ingestion of a small amount of the drug in the stomach. Allergic reactions also manifest themselves. They are included in the occurrence of skin rashes, itching, and swelling of the nasal mucosa. To avoid problems, it is worth exploring the contraindications and the way you take the medication.  

Overdose

Overdose in some cases occurs due to improper intake of medication. She manifests herself in the form of symptoms of intoxication with alpha sympathomimetics. What does this mean? The person starts to be persecuted by constant insomnia. In addition, there is drowsiness. A person wants to sleep, but can not. Against this background, dizziness develops, nausea is possible. In children often there is an intensified tachycardia. There is a sharp jump in blood pressure.

Intoxication with an active ingredient in babies can cause seizures. There were cases of man getting into a coma. Do not exclude the appearance of high blood pressure, while breathing is difficult. This is really serious. The main thing is to start fixing the problem in time.

When using an increased dose of the drug, a strong overexcitation of the central nervous system is possible. Man begins to pester hallucinations. In some cases, convulsions appear. If the central nervous system is on the contrary in a depressed state, then the symptomatology is quite different. So, a person feels a significant drop in temperature, he always wants to sleep. The most dangerous symptom is a coma. Symptoms of intoxication Lazorin and the transition between the active and the oppressed phase can be erased.

With severe intoxication, the active ingredient may develop nausea and severe sweating. It is not excluded the occurrence of arrhythmia, fever and complete cardiac arrest. All this indicates that it is not recommended to change dosage independently.

Elimination of an overdose is not at all complicated. It is enough to rinse the nasal passages, then prescribe symptomatic therapy. If the product has got into the stomach, do a lavage. 

Interactions with other drugs

The interaction of Lazorin with other drugs is possible, but only if they have a different effect. The fact is that the simultaneous use of medicines with the same action can lead to the accumulation of the main components in the body. All this will contribute to the development of an overdose. Symptomatics can be varied, and even dangerous for health. Therefore, it is necessary to take this fact into account. Regarding other interactions, information is not available.

Simultaneous use of the drug together with MAO inhibitors or tricyclic antidepressants is fraught with serious consequences. So, a significant jump in blood pressure is not excluded. That's why the doctor does not recommend recourse to self-treatment. It is mandatory to seek help from a specialist and talk about the use of other drugs every day. It is only on the basis of such data that it is possible to draw up an ideal treatment regimen. However, it will not do any harm. Proper use of the medication will eliminate the problem effectively. 

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Storage conditions

Storage conditions Lazorin is recommended to be fully observed. Medical preparations require special attention to themselves. The place of their storage should correspond to many indicators. It is important to observe the optimum temperature and humidity level. As for the temperature, it should not go beyond 25 degrees. This is considered the norm. Otherwise, Lazorin comes to complete unreadiness.

Naturally, humidity plays a significant role. The storage location of the preparation should be dry and not subject to the negative influence of direct sunlight. This will protect the medication from premature spoilage. Of course, it's worth to protect the kids. Keep the product better in a specially designated place, namely a medicine cabinet. There, all the necessary conditions are met. You need to follow the appearance of the packaging. Keep the drug in a standard form. It is necessary to avoid puncture of the can. This will only lead to damage to the drug itself, the surrounding from this no danger will not. 

Shelf life

Shelf life of the drug is 3 years. But this is just a figure if you do not keep the right storage conditions. The fact is that it is not responsible for the duration of the "exploitation" of the funds. It is important to provide the medication with ideal conditions. To do this, it is enough to observe a temperature regime of 25 degrees Celsius. To give a tool to the influence of cold and direct sunlight is not worth it. It is afraid of increased humidity. These factors are worth considering. After opening, the medicine is not stored for 3 years, a maximum of 1-3 months.

You need to follow the external data of the drug. If the can is damaged, then its further use is prohibited. Do not use the product when changing its consistency, color and odor. Children can harm the balloon, so you need to store Lazorin in a place where they do not exactly get.

Only proper observance of the storage conditions will allow using the medication for the given time without harm to health. All this must necessarily be taken into account.