Laxigal

Laxigal is one of the drugs that actively combat poor bowel function. Simply put, the drug eliminates constipation. This problem occurs with improper nutrition. It mainly occurs in older people. You should not neglect the use of the drug, because it can really help.

Indications Laxigal

Indications for use Laxigal - acute functional constipation. It occurs most often when changing lifestyle, including nutrition. It is observed when traveling, in a different climate, etc. Simply put, when changing location.

Laxigal actively eliminates secondary constipation. It develops mainly against the background of other diseases. Laxigal regulates and facilitates stool in patients with rectal pathologies. These processes include cracks that occur on the mucous membrane of the rectum, painful hemorrhoids and other problems.

When preparing for an X-ray or endoscopic examination of the gastrointestinal tract, it is also recommended to resort to using this medication. It allows you to cleanse the intestines and thus allows you to better examine the presence/absence of pathologies. The medication is sold in pharmacies without a prescription, but you need to take it after a doctor's prescription. Self-treatment can lead to a complete reluctance of the intestines to "work". This will entail the need for constant use of a laxative.

Release form

Laxigal is presented in the form of drops for oral administration. They are presented as a transparent liquid, the color of which can vary from colorless to slightly yellow-brown. Contains the product and auxiliary components, including a 70% sobitol solution, sodium ethyl parahydroxybenzoate, 35% hydrochloric acid, and purified water.

Laxigal is sold in two types. Thus, one bottle contains 10 ml. The bottle itself has a dark shade, and is in a cardboard box. There is also a 25 ml version of the drug, the "packaging" is similar. One milliliter contains 75 mg of the active ingredient - sodium picosulfate.

The concentration is no different. There is no difference between 15 and 25 ml, only in quantity. It is worth buying drops in the form recommended by the doctor. A large bottle may be unnecessary, especially if the drug needs to be used only once. The medication is not dangerous, but its systematic use "without purpose" can lead to problems with the intestines.

Pharmacodynamics

Pharmacodynamics Laxigal is an active laxative. This medication is widely used in modern medicine. The active form of the drug is formed under the influence of microorganisms in the intestine. The drug is able to excite the nervous structures of the intestinal wall. This process allows you to speed up the process of emptying. The consequence of this process is the acceleration of the movement of intestinal contents, in cases where there are problems. The absorption of electrolytes and water is significantly reduced. The drug begins to act 10-12 hours after administration.

That is why it is recommended to use the product directly at night. When entering the body, Laxigal is not absorbed from the gastrointestinal tract at all, and is not subject to hepatic-intestinal circulation. The medication does not leave a "sediment" in the body and is completely excreted along with the contents of the intestine. The liver and kidneys are not exposed to negative effects.

Pharmacokinetics

Pharmacokinetics Laxigal - the drug is not absorbed from the gastrointestinal tract. Moreover, the hepatic-intestinal circulation is also not visible here. The drug enters the intestine directly and begins its active "work" there. The effect of the first pass through the liver is not observed.

Laxigal, penetrating the body, actively excites the nerve fibers located in the intestinal walls. This occurs under the influence of microorganisms that are in the intestine itself. All this significantly accelerates the process of emptying the intestine. The contents of the intestine actively move, the degree of absorption of liquid decreases. The active substance of the drug is sodium picosulfate. The peak of its activity develops after 12 hours after taking the drug. As stated above, it is recommended to use the drug immediately at night. Because the active phase of action in this case will be in the morning hours. It should be noted that one bowel cleansing may not be enough. Therefore, on the day of "cleansing" it is advisable to be at home. This will eliminate the likelihood of discomfort.

Dosing and administration

The method of application and dosage are individual and are discussed exclusively with the attending physician. Laxigal is taken orally, for adults and children over 10 years old - in a single dose of 12-24 drops. For children from 4 to 10 years old, a single dose of 6-12 drops is sufficient. Naturally, as repeatedly mentioned above, the drug should be taken before bedtime. After all, its effect will begin no earlier than 10-12 hours.

As for repeated use, it is possible. But the dose should be reduced or increased. This manipulation is performed depending on the effect that was obtained after the first use. It is forbidden to use the product without supervision for more than 10 days. In particular, self-medication is prohibited.

The methods of administration and dosage may vary, depending on the problem that needs to be addressed. If it is a serious disease or examination of the gastrointestinal tract, it is not worth taking Laxigal exactly as described in the instructions. Individual doses are developed for such purposes.

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Use Laxigal during pregnancy

The use of Laxigal during pregnancy should be done only as prescribed by a doctor. The main contraindication is the first trimester. During this period, there is a high risk of harm to both the mother's and the child's body. The woman is actively preparing for childbirth. More precisely, her body is rebuilding itself in every possible way for this process. In this regard, the immune system weakens. Therefore, the use of any drugs can only worsen the situation.

The first trimester is dangerous due to the possibility of developing pathologies in the child. Miscarriage is possible. The drug is used with special caution during breastfeeding. The drug can penetrate the child's body with mother's milk. Possible negative effects have not been studied. In this regard, even seemingly safe tablets should not be used. In any situation, it is necessary to weigh the positive effect on the mother's body with possible negative consequences for the baby.

Contraindications

Hypersensitivity to the main components of the drug is the main prohibiting factor for taking the medication. In particular, it is worth noting the substances of the triarylmethanol series and parabens. This can lead to the development of a serious allergic reaction.

In case of acute intestinal obstruction, the drug is also not used. In this case, you need to act radically, drops will not have any effect. In the presence of a strangulated hernia, peritonitis, acute inflammatory diseases of the abdominal organs - admission is prohibited. A similar ban applies to severe abdominal pain, nausea, vomiting that do not have a precise genesis.

In no case should the medication be used in the presence of bleeding in the gastrointestinal tract, metrorrhagia, spastic constipation, severe dehydration, cystitis. Children under 4 years of age and pregnant women should not be treated with this medication. The drug is prescribed to nursing mothers with special caution and only if there are serious medical indications.

During treatment with the drug, the development of cardiac glycoside sensitivity is not excluded. Electrolyte disturbances can occur when these drops are combined with diuretics and glucocorticosteroids. The laxative effect is significantly reduced by antibiotics.

Side effects Laxigal

Side effects of Laxigal if used incorrectly can lead to dehydration. It is possible that the pressure will drop, mild abdominal pain, severe diarrhea, electrolyte and water imbalance will occur. In some cases, there may be weakness and cramps.

What causes side effects? As mentioned above, this is due to improper use of the drug. Many people do not know that they have increased hypersensitivity to some components of the drug. That is why the occurrence of adverse symptoms indicates that people have problems. Not all patients want to consult a doctor. Self-medication comes to the rescue here. All this is fraught with serious consequences.

It often happens that the instructions for use are completely ignored. Therefore, a person not only takes an overdose, but also, without waiting for a lightning-fast result, repeats the action. This leads not only to the appearance of side effects, but also to a severe overdose.

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Overdose

Overdose occurs due to uncontrolled intake of the medication. The symptoms are as follows: nausea, vomiting, severe diarrhea, abdominal pain. Dehydration of the body due to severe intestinal disorder is possible. In some cases, blood pressure drops.

Chronic overdose may result in colon mucosal ischemia, secondary hyperaldosteronism, urolithiasis, and renal tubule damage. This is mainly due to taking doses that are several times higher than therapeutic doses. Increased production of the hormone aldosterone by the adrenal cortex is possible, accompanied by muscle weakness and high blood pressure.

In order to eliminate the problems that have developed, it is worth resorting to gastric lavage. The drug should be removed from the body to stabilize its functioning. Correction of water-electrolyte imbalance is also carried out. In case of severe pain, antispasmodics are used. Further treatment depends on the symptoms.

Interactions with other drugs

Interaction of Laxigal with other drugs is possible, but only if they do not have the same effect. Taking several laxative medications at once is prohibited. Such interaction will lead to severe dehydration of the body. It will be difficult to restore the water-electrolyte balance.

Increased sensitivity to cardiac glycosides is possible.

GCS, diuretics increase the risk of developing electrolyte disorders. If a person takes broad-spectrum antibiotics, then one should be prepared for the fact that the laxative will not give the expected effect. Because these drugs significantly reduce the laxative effect. Should not be used daily without medical supervision for more than 10 days.

Children should use only as directed by a physician.

For other interactions, consult a specialist. In any case, if you use any medications simultaneously with a laxative, you must inform your doctor about it.

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Storage conditions

The storage conditions of Laxigal must be observed in full force. The fact is that improper storage leads to rapid deterioration of the medicine. Any drug requires compliance with the temperature regime and humidity level. Thus, drops should be stored at a temperature of 10-25 degrees. The product should not be frozen under any circumstances.

The optimal conditions are a dry, dark place, without excess sunlight and humidity. Naturally, children should be protected from access to the drops. They do not pose any particular danger. But if the baby takes too many of them, there is a risk of complete dehydration. This is fraught with serious consequences.

After opening, the bottle must be stored in a special way. The fact is that the expiration date in this case no longer plays any role. After opening, the medicine can be used for 1-2 months. In this case, it is worth observing the appearance of the drug. It should not change its taste and color.

Shelf life

The shelf life is 2 years. But it is worth considering the fact that after opening the bottle, you can take it for no more than 2 months. In this case, it is advisable to create a certain temperature regime. 10-25 degrees will do. In no case should the product be placed in the refrigerator. It is not used in frozen form.

Laxigal can be placed in a medicine cabinet. But before that, make sure that all necessary storage conditions are met. The medicine cabinet should not be exposed to high temperatures. Laxigal should be kept in a dry, warm place with moderate humidity. This is the only way to extend the “lifespan” of the drug. Children should not have access to Laxigal.

The external appearance of the medication should also be monitored. Any change in appearance, taste and smell should be noticed. In this case, the drug should be thrown away. After the expiration date, the product cannot be used. After all, it can lead to serious side effects.