The administration of the drug solution is carried out by the method, but the method of in / in use is forbidden, since it even in usual dosages can provoke the appearance of hypoglycemia in severe form. Prolonged properties of drugs provide exactly the injection in the subcutaneous fat layer.
During treatment, it is necessary to follow a certain regimen, and also to correctly perform the procedure of drug administration.
There are no clinically significant differences in the case of drug administration to the deltoid muscle, abdomen or thigh region. However, while remaining within the most suitable areas for the introduction, it is necessary to change the injection site during each new procedure.
The medicine can not be diluted or mixed with other drugs.
In Lantus contains insulin, which has a prolonged effect. It is required to enter it once a day, and the procedure should always be carried out at the same time. The regime is selected for each separately - the size of the doses, the time of the procedure, etc. It is allowed to use the medicine in combination treatment of type 2 diabetes mellitus (together with hypoglycemic drugs).
It should be taken into account that the ED of Lantus is different from the indices of ED of other insulin products.
In elderly people, due to a progressive disorder in the work of the kidneys, the body's need for insulin can be constantly reduced. Therefore, in the case of a person with disorders of kidney function, there may be a reduced (in comparison with patients with healthy renal function) the need for this substance.
In case of impaired hepatic function, the need to receive insulin may also decrease (as the metabolism of this substance slows down, and gluconeogenesis is reduced).
When implementing the transition to Lantus from other types of insulin medicines:
In case of using insulin having a high or medium extent of exposure, after the transition, it may be necessary to correct the size of the dose of the background insulin, and with it the change in the concomitant treatment. To reduce the likelihood of hypoglycemia in the night, and also in the morning, people who change the mode of taking background insulin (switching from 2-time injections (application of NPH insulin) to disposable (Lantus administration)), it is necessary to reduce its dosage during 20-30% first weeks of treatment. At the same time, it is necessary to slightly increase the dosage of insulin taken with food. After 2-3 weeks, the dose sizes are adjusted taking into account the characteristics of the patient.
In humans, which have antibodies to human insulin, during the use of the medicine, the body can give a modified reaction to this substance. Due to such a violation, dosage adjustment may be required.
Dosage should be changed in case of a change in lifestyle, weight, and other factors that can affect the properties of insulin.