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With a lace
Last reviewed: 23.04.2024
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Texamen is a medicine with analgesic properties.
Indications Texan
It is used in people with diseases in the field of musculoskeletal tissues, which are degenerative and inflammatory in nature, and accompanied by painful sensations:
- gout;
- rheumatoid arthritis;
- osteoarthrosis with osteochondrosis;
- ankylosing spondylitis.
The injections are used to quickly eliminate pain that occurs due to:
- injuries caused by injuries;
- myositis with tendinitis;
- lesions in the ligament;
- lumbago, polyarthritis and periatritis, as well as neuralgia.
Release form
The release is made in the form of a powder with a liquid-solvent (in vials), as well as in tablets. Inside the box there is one such bottle or a blister pack with 10 tablets.
Pharmacodynamics
The active element of the drug is part of the group of oxycomas and has antipyretic, anti-inflammatory and analgesic effects. The mechanism of action is based on the slowing down of the processes of the binding of PG and the metabolism of arachidonic acid, and in addition to the suppression of COX activity.
Texamen A promotes inhibition of histamine release, as well as the rate of phagocytosis, thereby reducing inflammation.
The drug reduces the influence exerted by bradykinin on the endings, inhibits the excretion of macroenergetic ligaments, normalizes the strength of the lysosome walls, and further strengthens the strength of the capillaries.
Pharmacokinetics
The active ingredient is absorbed completely and at high speed inside the gastrointestinal tract. The level of bioavailability is 100%. Peak values are noted after 2 hours after using the drug. About 99% of the active substance is synthesized with the proteins in the plasma.
Metabolic processes occur in the liver. Disintegration products are excreted in the urine, as well as bile. The substance of tenoxicam can penetrate the hematoplacental barrier (in pregnant women), as well as the BBB.
Dosing and administration
The medicine in tablets is consumed internally - the standard mode of administration: the use of 20 mg of the drug every day.
In the acute stage of gout, 2 tablets of drugs with a volume of 20 mg for 2 days are taken once a day, and then switched to the daily intake of the 1st pill. You can take Texamen for 1-2 weeks.
To eliminate the expressed painful sensations, it is required to apply the medicine in the form of injections. It is necessary to administer the drug intramuscularly - according to the 1st vial, the volume of which is 20 mg, every day. The medicine in ampoules can be used for a maximum of 5 days.
Use Texan during pregnancy
In animal tests, teratogenic properties were not detected. There is no information on the negative effect of the active drug element on the fetus.
The medicinal component is able to excrete with the mother's milk, so the drug can not be administered to women who are breast-feeding.
Contraindications
The main contraindications:
- the presence of intolerance with regard to the elements of the drug;
- gylactasia;
- presence in the anamnesis of the "aspirin triad";
- diabetes;
- disease in the digestive system (ulcer or gastritis);
- pathologies affecting liver function;
- heart failure;
- primary hypertension;
- coagulation disorders;
- diseases associated with the vestibular apparatus;
- problems with auditory perception;
- application in childhood.
Side effects Texan
Use of the drug leads to the development of certain side-effects:
- disorders related to the digestive system: bloating, stool disorders, gastropathy with heartburn, pain in the epigastric region, stomatitis with anorexia, vomiting, erosion and increased ALT or AST;
- hematopoietic disorders and CAS functions: increased blood pressure, thrombocytopenia, tachycardia, and agranulocytosis;
- problems affecting the work of the National Assembly: the state of depression, severe excitability or drowsiness, dizziness and migraine attacks, and in addition irritation of the eye mucosa, ear noise and changes in visual or auditory perception;
- Other: occasionally there are spasms of bronchi, hyperhidrosis, signs of allergy, angioedema, skin itching and an increase in the level of urea nitrogen.
The Texamine injections are tolerated well enough, only occasionally provoking the development of common side-effects.
Overdose
When using the drug in large portions, a feeling of drowsiness or agitation develops, vomiting, pain in the epigastrium, and in addition, a disorder of the stool. With severe intoxication, convulsions, a sense of disorientation and bleeding in the gastrointestinal tract arise.
Texamen does not have an antidote, so when poisoning it is necessary to carry out symptomatic measures.
Interactions with other drugs
Corticosteroids, salicylates, and also funds from the category of NSAIDs increase the risk of ulcers on the stomach walls.
The drug increases the severity of the action of sulfonylurea derivatives, and in addition to indirect anticoagulants. The substance of probenecid increases the rate of excretion of tenoxicam from the body.
Texamen reduces the level of SG inside the blood.
Drugs with potential nephrotoxicity, antagonists of serotonin endings, antiaggregants, as well as diuretic drugs combined with Texamen is prohibited.
When combined with antibiotics from the quinolone group, convulsive activity increases.
The drug effectiveness of the mifepristone element decreases when combined with the drug.
Storage conditions
The Texman should be kept at temperatures within 25 ° C.
Shelf life
The Texman is allowed to be used for 2 years from the date of release of the drug.
Analogues
Among the structural substitutes for the drug are Tobitol with Tenikam and Tenoktil.
Medivalis and Meloxicam drugs are analogues of the drug.
Reviews
The Texman in the injections is transferred perfectly, without leading to the development of local negative effects, if the aseptic rules are observed.
In medical reviews on the effectiveness of drugs, there is a high rate of its effect, and this is extremely important in the case of the need to eliminate severe pain.
Most reviews about the drug are positive, and mark its qualitative therapeutic effect in the treatment of inflammations associated with the bone system.
Attention!
To simplify the perception of information, this instruction for use of the drug "With a lace" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.