Capsules are for internal use. It is recommended to take them with food. During the treatment period it is important to observe the regularity of use, not missing the dose. The duration of the therapeutic course and dosage sizes are prescribed by the treating doctor.
Typically, the daily dosage is twice 50 mg. The size of the dose can vary according to the patient's condition. The maximum for the day is not more than 250 mg, and the daily average is 100 mg. Often, the course of therapy is quite long (for several months).
For people with impaired renal activity, dosage adjustment is required (taking into account the level of filtration in the kidneys).
If necessary, perform local anesthesia (with the help of epinephrine or norepinephrine), the dosage of these pain relievers should not exceed 0.1 mg for 10 minutes, as well as 0.3 mg for 1 hour.