The active substance of the drug is Framicetin, which is included in the category of aminoglycosides of local use and has antimicrobial properties. He has high medicinal values inside the tissues of the nasal mucosa, as well as paranasal sinuses. The substance has a pronounced bactericidal activity, affecting most of the strains of gram-negative, as well as gram-positive microbes, which provoke the development of infectious processes in the upper respiratory system. Resistance to framicetin is almost not observed.
Framamycetin actively acts against corynebacteria, listeria monocytogenes, staphylococci meti-S, acitetobacter (mainly Baumann aukinetobakterii), moraxelly kataralis, campylobacter, citrobacter freundi, Citrobacter koseri. In addition, also against enterobacter anagenes, enterobacter of cloaca, Escherichia coli, Influenza sticks, Klebsiella, Morgan bacteria, Providence of Rettgera Proteus mirabilis, vulgar proteium, Salmonella, Serratia, and Shigella and Yersinia.
Pasteurells have moderate sensitivity to the effect of Framicetin.
To the influence of the substance are resistant such microorganisms: enterococci, Nocardia asteroides, staphylococci meti-R (resistance is about 30-50%, more pronounced hospital), streptococci and Alcaligenes denitrificans. In addition, Burkholderia, Flavobacterium sp., Stewart's progeny, Pseudomonas aeruginosa, stenotrophomonas maltophilia, chlamydia, resistant anaerobes, and with them mycoplasma and rickettsia.