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Inoculation against tularemia

, medical expert
Last reviewed: 10.08.2022
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The causative agent of tularemia - Francesella tularensis - was isolated from more than 100 species of mammals, birds and insects; mainly people who have contact with animals are infected, but contamination is possible with the use of contaminated meat and water, with bites of ticks and other vectors.

Vaccination against tularemia live dry - lyophilized culture of live tularemia microbes of vaccine strain 15 NIIEG. Shelf life 2 years, store temperature not higher than 8 °. The vaccine is administered from the age of 7 (from 14 years in the field-type foci) once dermally or intradermally. Before vaccination, the presence of specific immunity with the help of one of the serological or skin-allergic reactions is determined without fail, only those with a negative reaction are vaccinated. One dose for skin administration - 2 drops (210 8 microbial cells), with intradermal - 0.1 ml (10 7 microbial cells). Revaccination according to indications after 5 years with the same dose. Simultaneous dermal vaccination of adults with live vaccines against tularemia, brucellosis and plague (in different parts of the body) is allowed. A diluted vaccine against tularemia is used for 2 hours.

The skin tularemia vaccination is performed on the outer surface of the middle third of the shoulder with a vaccine diluted with a solvent in the volume indicated on the ampoule label. After 2 drops of the vaccine in two places (with a distance of 30-40 mm) on the outer surface of the middle third of the shoulder, 2 parallel incisions of 10 mm in length are made.

Immunity is formed 20-30 days after vaccination, it persists up to 5 years.

trusted-source[1], [2], [3], [4], [5], [6], [7], [8], [9]

Reactions to the injection of vaccination against tularemia

Local reaction should develop in all grafted skin: from 4-5, less often on the 10th day of hyperemia and edema with a diameter of up to 15 mm, small vesicles along the incisions. From 10-15 days a crust is formed, leaving a hem behind, sometimes an increase in the lymph nodes. With the intradermal route, the local reaction lasts up to 9 days - an infiltration up to 40 mm, sometimes with the reaction of regional lymph nodes. The general reaction to vaccination against tularemia is rare: malaise, headache, temperature to 38 ° 2-3 days. An allergic reaction to the 3-4th week is rare. In patients with tularemia or revaccinated reactions develop more violently, but their extinction goes faster.

Attention!

To simplify the perception of information, this instruction for use of the drug "Inoculation against tularemia" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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