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Hondroflex
Last reviewed: 04.07.2025
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Hondroflex is included in the category of NSAID medications. Contains the active element chondroitin sulfate.
Indications Hondroflex
It is used to treat people with localized pathologies affecting the spine and joints and having a degenerative-dystrophic nature (including osteoarthritis with osteochondrosis).
Release form
The drug is released in the form of an ointment, in tubes of 30 g. The package contains 1 such tube.
Pharmacodynamics
Hondroflex has an anti-inflammatory and chondroprotective effect. It contains the active element chondroitin sulfate, which affects the metabolism of phosphorus with calcium and prevents the degeneration of cartilage tissue. The substance inhibits the process of bone tissue resorption, and also prevents the compaction of connective tissues and helps improve the production of fluid contained inside the joints.
The medication improves joint mobility, participates in the formation of bone and cartilage tissue, and in addition protects the latter from damage and improves regeneration processes.
After external treatment, the substance slows the progression of osteoarthritis, reduces inflammation and pain in the joints and improves the condition of patients.
The anti-inflammatory effect of the drug develops by acting on the inflamed area of the cell, stimulating the binding of proteoglycans to hyaluronic acid, and in addition, by suppressing the activity of proteolytic enzymes.
The dimethyl sulfoxide contained in the drug promotes deeper penetration of chondroitin into the epidermal layers.
Chondroitin sulfate is a high molecular weight mucopolysaccharide (its molecular weight is about 20,000-30,000).
Pharmacokinetics
Plasma values of Cmax of chondroitin with external treatment develop after 3-4 hours, and inside the synovium this indicator is noted after 4-5 hours. The level of bioavailability after external application is 13%.
Excretion of chondroitin occurs primarily via the kidneys.
Dosing and administration
Hondroflex is used for external treatment. The medicine should be applied in a thin layer to the epidermis in the area of inflammation. Do not allow the medicinal substance to come into contact with areas of the epidermis whose integrity is compromised, as well as with mucous membranes. After finishing the treatment procedure, wash your hands thoroughly.
The duration of the treatment cycle and the sizes of the dosage portions are selected by the attending physician. Often, 2-3 ointment treatments per day are prescribed.
On average, treatment usually lasts 14-21 days. If necessary, and provided that the patient tolerates the treatment without complications, the course can be extended with the permission of the attending physician.
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Use Hondroflex during pregnancy
Hondroflex is prohibited for use during breastfeeding or pregnancy.
Contraindications
Main contraindications:
- the presence of severe sensitivity to chondroitin sulfate or additional components of the drug;
- It is prohibited to prescribe to people who suffer from thrombophlebitis.
Side effects Hondroflex
The ointment is often tolerated by patients without complications. Its isolated use resulted in the appearance of skin hyperemia or itching and a burning sensation in the treatment area, as well as rashes.
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Storage conditions
Hondroflex should be kept out of the reach of small children. Temperature values are within 15-25°C. The ointment should not be frozen.
Shelf life
Hondroflex can be used within 36 months from the date of production of the therapeutic drug.
Application for children
The medicine cannot be used in pediatrics.
Analogues
The analogs of the drug are Mucosat, Structum, Artrodol, Artron Hondrex and Artra Chondroitin with Chondroitin-Fitopharm, Chondrolon and Chondroitin ointment.
Reviews
Hondroflex receives quite good reviews from patients who have used the drug. The comments also indicate that the drug demonstrates higher efficiency when used in combination with therapeutic exercises, as well as with the implementation of procedures that enhance blood supply processes.
A large number of positive comments about the ointment are left by elderly people.
There are also those for whom the medication did not help at all, which is also reported on the forums.
Doctors consider Hondroflex in the form of an ointment to be more effective than the same in the form of oral capsules.
Attention!
To simplify the perception of information, this instruction for use of the drug "Hondroflex" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.