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Hondroflex
Last reviewed: 23.04.2024
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Hondroflex is included in the NSAID medication category. Contains the active element Chondroitin Sulfate.
Indications Hondroflex
It is used to treat people with a localized type of pathologies affecting the spine and joints, and having a degenerative-dystrophic nature (among them osteoarthritis with osteochondrosis).
Release form
The release of the drug is implemented in the form of ointment, in tubes of 30 g. The package contains 1 such tube.
Pharmacodynamics
Hondroflex has anti-inflammatory and chondroprotective effect. Its composition contains the active element chondroitin sulfate, which affects the metabolism of phosphorus with calcium and prevents the degeneration of cartilage tissue. The substance inhibits the process of bone tissue resorption, and also prevents the consolidation of connective tissues and helps to improve the production of fluid contained within the joints.
The drug improves articular mobility, is involved in the formation of bone and cartilage tissues, and in addition protects the latter from damage and improves regeneration processes.
After external treatment, the substance inhibits the progression of osteoarthritis, reduces inflammation and pain in the joints and improves the condition of patients.
The anti-inflammatory effect of the drug is developed by acting on the inflamed part of the cell, stimulating the binding of proteoglycans to hyaluronic acid, and in addition by suppressing the activity of proteolytic enzymes.
Dimethyl sulfoxide contained in the drug contributes to a deeper passage of chondroitin in the epidermal layers.
Chondroitin sulphate is a high molecular weight mucopolysaccharide (its molecular weight is about 20,000-30000).
Pharmacokinetics
Plasma Cmax values of chondroitin during external treatment develop after 3-4 hours, and inside the synovia, this indicator is noted after 4-5 hours. The level of bioavailability after external application is 13%.
Excretion of chondroitin occurs mainly through the kidneys.
Dosing and administration
Hondroflex is used for external processing. Apply the drug should be a thin layer on the epidermis in the area of the inflammation. Do not allow the ingress of medicinal substances on the epidermis, the integrity of which is broken, as well as mucous membranes. After finishing the treatment, wash your hands thoroughly.
The duration of the treatment cycle and the size of the dosage portions are selected by the attending doctor. Often prescribed 2-3-fold treatment ointment per day.
On average, treatment usually lasts 14-21 days. When a need arises, and provided that the patient tolerates the treatment without complications, the course is allowed to be extended with the permission of the attending doctor.
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Use Hondroflex during pregnancy
Hondroflex is forbidden to appoint when breastfeeding or pregnancy.
Contraindications
Main contraindications:
- the presence of strong sensitivity in relation to chondroitin sulfate or additional elements of the drug;
- It is forbidden to appoint people who suffer from thrombophlebitis.
Side effects Hondroflex
Ointment is often tolerated by patients without complications. Its single use led to the appearance of skin hyperemia or itching and burning sensation in the treatment area, and in addition to this rash.
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Storage conditions
Hondroflex must be kept in a place inaccessible to small children. Temperatures are within 15-25 ° C. Ointment can not be frozen.
Shelf life
Hondroflex can be used within 36 months of the production of a therapeutic drug.
Application for children
Do not use the medicine in pediatrics.
Analogs
Analogues of the medication are the drugs Mukosat, Struktum, Artradol, Arthron Hondrex and Artra Chondroitin with Chondroitin-Fitopharm, Hondrolon and Chondroitin ointment.
Reviews
Hondroflex receives fairly good reviews from patients using the medication. The comments also indicate that the drug demonstrates higher efficiency when used in combination with therapeutic exercises, as well as with the implementation of procedures that enhance the blood supply processes.
A large number of positive comments about the ointment leave the elderly.
There are also those to whom the medication has not helped at all, which is also reported on the forums.
Doctors also consider Hondroflex as an ointment more effective than its oral capsule form.
Attention!
To simplify the perception of information, this instruction for use of the drug "Hondroflex" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.