Helminthox

Gelmintox has anthelmintic properties.

Indications Helminthox

It is used to eliminate ancylostomiasis, enterobiasis, and also ascariasis.

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Release form

The product is released in the form of tablets: (form 125 – 6 pieces per pack; form 250 – 3 pieces per package).

It is also produced as an oral suspension – in 15 ml vials.

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Pharmacodynamics

Gelmintox is an antihelminthic drug that causes neuromuscular blockade in helminths, as well as spastic muscle paralysis. These helminths are then excreted from the body with feces through intestinal peristalsis.

The drug is effective against both immature and mature helminths of both biological sexes: roundworms with pinworms, as well as hookworms. The drug does not have an exciting effect, so it does not cause migration of parasites. It does not affect migrating larvae of parasites.

Pharmacokinetics

The drug is practically not absorbed from the gastrointestinal tract. Peak levels in the blood are observed within 1-3 hours.

Part of the active substance undergoes hepatic metabolism. Approximately 93% of the drug is excreted through the intestines, and the remaining 7% of the substance through the kidneys.

Dosing and administration

Use of tablets.

The tablets are taken orally, at any time of the day. They can be taken on an empty stomach. Concomitant use of laxatives is not required.

To eliminate enterobiasis or ascariasis - the size of the children's portion: 1 tablet of 125 mg / 10 kg. For adults whose weight is less than 75 kg, a portion of 3 tablets of 0.25 g is required. People with higher weight indicators need to take 4 tablets of 0.25 g.

Use of medicinal suspension.

Before use, shake the bottle with the suspension thoroughly. 1 ml of the drug contains 50 mg of the active ingredient, and 1 measuring spoon contains 125 mg of the substance.

During therapy for ascariasis or enterobiasis, the pediatric dosage is a single dose of 1 spoon/10 kg. An adult weighing less than 75 kg should take 6 spoons of the drug, and those weighing more than 75 kg should take 8 spoons per dose. After 3 weeks of therapy, the drug should be repeated in similar portions to prevent new infection.

The course of treatment for ankylostomiasis lasts 3 days. The size of the children's dose is 0.25 mg / 10 kg. For adults with weight values u200bu200bover 75 kg, the daily portion is 2 g.

During the deworming period, it is necessary to thoroughly clean the premises and wash children's toys in the house. In addition, it is necessary to change underwear every day and iron bed linen. Therapy should be carried out for each family member. To prevent re-infestation, it is necessary to change your underwear every day, wash your hands thoroughly and avoid scratching the skin areas in the perineum. After the course is completed, a control fecal test is performed.

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Use Helminthox during pregnancy

Pyrantel-containing medications are not recommended for pregnant women. Gelmintox may only be used in situations where it is not possible to use a safer alternative for the pregnant woman.

Contraindications

Among the contraindications:

• breastfeeding period;
• the presence of hypersensitivity to the drug;
• myasthenia;
• liver pathologies or liver failure.

Side effects Helminthox

The use of the drug occasionally causes the following side effects:

• vomiting with nausea, loss of appetite, diarrhea, abdominal pain;
• development of hives or itching;
• increased transaminase values within the liver;
• a feeling of fatigue, development of headaches, insomnia, and also dizziness;
• hearing disorders.

Overdose

In case of overdose, severe poisoning does not develop. To eliminate symptoms, it is necessary to perform gastric lavage.

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Interactions with other drugs

Pyrantel increases theophylline levels in the blood.

Combined use with sorbents may lead to a weakening of the properties of the active element of the drug.

It is prohibited to combine the medication with piperazine or levamisole.

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Storage conditions

Helmintox must be kept in standard conditions for medicinal products. Temperature indicator – within 25°C.

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Shelf life

Gelmintox (both suspension and tablets) can be used for 3 years from the date of release of the drug.

Application for children

The drug in tablets can be prescribed to children over 6 years of age.

The suspension can be prescribed to children under 6 years of age weighing more than 12 kg.

Analogues

The analogs of the drug are Pirantel and Nemocid (both drugs are available in suspension and tablets).

Reviews

Gelmintox is the drug of choice in the treatment of enterobiasis with ascariasis (along with Pirantel). Helminthiasis is a fairly common disease that mainly develops in children, so this drug is used quite often. Clinical tests of its effectiveness have demonstrated very high rates (94-100%) in the treatment of the above-mentioned invasions. Another advantage of the drug, judging by many reviews, is its good tolerability in children.

Due to its convenient dosage form and pleasant taste (suspension), it can be given to children without any problems, without causing a negative reaction. In the above-mentioned pathologies, a single use of the drug is enough for the child's tests for worms to give a negative result. There are isolated reports of the development of side effects in the form of mild abdominal pain and diarrhea, as well as minor nausea.

Often, the therapy took place without the development of negative reactions - this circumstance is due to the fact that Helmintox only immobilizes the parasites, and, as is known, when they die, toxic elements are released, causing the very development of side effects.

Another important factor is that no preparation or diet is required before using the drug; the drug can be taken without regard to food intake.