Glutoxim

Glutoxim, which contains the active substance glutamyl-cysteinyl-glycine disodium, is a drug with an immunomodulatory and systemic cytoprotective effect. It is a synthetic analogue of glutathione, an important antioxidant and cofactor for many enzymatic reactions in the body.

Glutathione performs a number of important functions in the body, including protecting cells from oxidative stress, regulating the immune response, and participating in the detoxification of toxic substances. Therefore, Glutoxim can be used to enhance the body's defenses and improve the general condition in various diseases.

Indications for the use of Glutoxim may include:

• Liver failure, including alcoholic and non-alcoholic fatty liver disease.
• Toxic liver damage caused by alcohol, drugs and other factors.
• Chronic diseases of the gallbladder and bile ducts.
• Other conditions associated with a violation of the redox balance in the body.

Like any medication, Glutoxim may have certain contraindications and side effects, so its use should be carried out under the supervision of a doctor.

Indications Glutoxima

1. Liver failure: Glutoxim can be used to treat various types of liver failure, including alcoholic and non-alcoholic fatty liver disease.
2. Toxic liver damage: The drug can be used to treat liver damage caused by toxins such as alcohol, drugs and other harmful substances.
3. Diseases of the gallbladder and biliary tract: Glutoxim can help improve the condition of patients with chronic diseases of the gallbladder and biliary tract.
4. Other conditions: The drug can be used as an immunomodulator and cytoprotector for other diseases associated with disturbances in the redox balance in the body.

An immunomodulator with a systemic cytoprotective effect, Glutoxim, containing disodium glutamyl-cysteinyl-glycine, is usually available in powder form for the preparation of a solution for injection.

Release form

Glutoxim is usually available in powder form for the preparation of a solution for injection.

Pharmacodynamics

1. Immunomodulatory action: Glutoxim helps modulate the immune system, helping to improve its functions. It can stimulate the body's immune responses by increasing the activity of immune cells such as lymphocytes, macrophages and neutrophils. This can help fight infections and other pathological processes more effectively.
2. Antioxidant action: Glutoxim has antioxidant properties, helping to protect cells from oxidative stress. It is able to neutralize free radicals that can damage cell membranes and cause inflammation.
3. Cytoprotective action: Glutoxim provides protection for the cells of organs and tissues of the body. It can improve the survival and functional state of cells, especially under conditions of stress or injury, such as infections, injuries or toxic exposures.
4. Stimulation of glutathione synthesis: Glutoxim can help increase the level of glutathione, an important antioxidant that plays a key role in protecting cells from oxidative damage and maintaining their function.
5. Improvement of metabolism: Glutoxim can help improve the body's metabolism, including amino acid metabolism, which can lead to more efficient use of nutrients and increased energy metabolism.

Dosing and administration

The method of administration and dosage of Glutoxim may vary depending on the patient's condition, characteristics of the disease and the doctor's recommendations. Usually the drug is administered intravenously, 5-10 ml of solution 1-2 times a day.

Use Glutoxima during pregnancy

Based on research and practical experience, a physician may recommend or prohibit the use of glutoxim during pregnancy depending on the clinical situation and the benefits to the mother and baby versus the potential risks.

Contraindications

1. Known Allergic Reaction: Patients with known allergies to components of the drug should avoid its use.
2. Autoimmune diseases: Glutoxim may enhance the immune response, so its use may be undesirable or contraindicated in patients with autoimmune diseases such as rheumatoid arthritis or systemic lupus erythematosus.
3. Pregnancy and breastfeeding: Information on the safety of Glutoxim during pregnancy and breastfeeding is limited, so its use requires consultation with a doctor.
4. Children and adolescents: Data on the safety and effectiveness of Glutoxim in children and adolescents may be limited, so its use in this category of patients requires special caution and medical supervision.
5. Liver or kidney failure: Patients with severe liver or kidney impairment should use caution when using Glutoxim as the organs may be unable to properly process the drug, which may lead to its accumulation in the body.

Side effects Glutoxima

1. Gastrointestinal disorders: Diarrhea, nausea, vomiting, or abdominal pain may occur.
2. Allergic reactions: May manifest as skin rash, itching, or angioedema.
3. Injection site reactions: Pain, redness, or swelling at the injection site may occur after intravenous administration. Injections.
4. Other rare side effects: Include headache, hypertension, increased sweating, and increased liver enzymes.

Overdose

1. Gastrointestinal irritation: Symptoms may include nausea, vomiting, diarrhea and abdominal discomfort.
2. Allergic reactions: Excessive consumption may cause allergic reactions such as skin rash, itching, swelling or anaphylactic shock in persons with hypersensitivity to the components of the drug.
3. Water and electrolyte imbalance: Excessive administration can lead to an imbalance of electrolytes, which can cause deterioration in general condition and various organic disorders.
4. Other possible consequences: Other undesirable effects are possible, which may be associated with the action of the components of the drug or its interaction with other substances.

Interactions with other drugs

Information about the interactions of Glutoxim (glutamyl-cysteinyl-glycine disodium) with other drugs may be limited due to a lack of research. However, given its immunomodulatory properties and systemic cytoprotective effect, interactions with other drugs are possible, especially with those that also affect the immune system or have a cytoprotective effect.