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Gepa-merc
Last reviewed: 23.04.2024
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Hepa-mertz has hepatoprotective properties; Included in the category of hypoazotemic drugs.
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Indications Gepa-merca
It is used in the following conditions:
- hepatic pathologies (among those acute or chronic stages), against which hyperammonemia is noted;
- encephalopathy in the liver.
As part of the combined treatment for disorders of consciousness (pre-comatose state or a full coma). Along with this, the medication is used as a corrective additive in a therapeutic nutritional diet in people with protein deficiency.
Gepa-mertz may be administered to eliminate poisoning in the event of alcohol intoxication.
Release form
The release of a substance is made in the form of a granulate for the manufacture of a medicinal liquid, which is packaged in 5 g sachets. Inside a separate box there are 30 such sachets.
Also sold in the form of a concentrate, in glass ampoules with a capacity of 10 ml. Packed 10 such ampoules.
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Pharmacodynamics
The active drug component, ornithine aspartate, is a participant in the ammonia carbamide biosynthesis process (Krebs-Genseleit cycle), and at the same time helps to produce insulin with GH. In addition, the substance accelerates the metabolism of proteins, improves liver activity (detoxification effect) and lowers blood ammonia.
Pharmacokinetics
The active element of Hep-merck is absorbed at high speed inside the stomach, entering the blood through the intestinal epithelium.
Excretion is carried out with urine.
Dosing and administration
It is necessary to use Gepa-merts after food intake. To make a 1-time portion of the medicament, in ordinary warm water (0.2 l) dissolve 1 sachet bag, which contains 5 g of drug granulate.
The infusion fluid is administered by the IV method in a portion of 20 g (4 ampoules of substance are required) per day. The average daily maximum allowable rate to which it is allowed to increase the portion, is 40 g (8 ampoules of drugs).
Use Gepa-merca during pregnancy
Pregnancy is not an absolute contraindication to the use of drugs, but to use it during this period should be exclusively under the supervision of a doctor.
At the time of therapy is required to cancel breastfeeding.
Contraindications
It is contraindicated to use the medication in the presence of disorders in the kidneys (blood values of creatine are 3 mg / 100 ml).
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Side effects Gepa-merca
Side effects when using the medication develop only one at a time. Among the disorders are vomiting, an allergic rash on the epidermis, or nausea.
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Overdose
Hep-mercem intoxication manifests itself in the form of potentiation of the negative symptoms of the drug.
With the development of disorders, first cancel the use of the drug, and then conduct gastric lavage, symptomatic procedures and prescribe the patient to receive activated charcoal.
Shelf life
Analogs
Analogues of the medication are the means Ornithine and Ornicketil.
Reviews
Gepa-mertz usually receives good reviews on the forums - patients who have used the drug, note its high efficacy and a small number of negative symptoms and contraindications.
Attention!
To simplify the perception of information, this instruction for use of the drug "Gepa-merc" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.