Medical expert of the article
New publications
Preparations
Gamalate B6
Last reviewed: 03.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
The drug Gamalate B6 is a psychostimulant and nootropic drug used for hyperactivity and attention deficit syndromes.
The drug is produced by the Spanish pharmaceutical company Ferrer Internacional.
The drug Gamalate B6 is available by prescription in pharmacies.
[ 1 ]
Indications Gamalate B6
Gamalate B6 can be prescribed to adult patients as an additional remedy for functional asthenic syndrome accompanied by the following symptoms:
- emotional instability;
- disorders of memory processes and concentration;
- depressive states;
- violation of social adaptation.
[ 2 ]
Release form
Gamalate B6 is produced in the form of tablets in blisters. One blister contains 10 tablets (in the shell). A cardboard box contains 2 blisters, i.e. 20 tablets.
Composition of the medicinal product:
- magnesium glutamate 0.75 g;
- γ-aminobutyric acid 0.75 g;
- γ-amino-β-hydroxybutyric acid 0.37 g;
- pyridoxine hydrochloride 0.37 g.
Pharmacodynamics
The pharmacodynamic properties of Gamalate B6 are represented by the complex action of such components as 4-aminobutanoic acid, amino-β-hydroxybutyric acid and pyridoxine: these substances are simultaneously natural components of the structure of brain tissue. The drug has a neuroregulatory effect on reactions occurring in the brain, and also has a slight calming and neurotonic effect.
GABA is formed by the breakdown of glutamic acid. This process is enhanced by GDA and pyridoxine. The end result is the formation of amino-β-hydroxybutyric acid, which can improve learning and stimulate memory.
In addition, GABA is able to re-transform into acid, which contributes to additional oxygen supply to brain tissue.
In case of disorders of the brain functionality, a deficiency of inhibition reactions is formed, which is associated with a decrease in the level of GABA, which is the main neurotransmitter of the inhibition process. The use of Gamalate B6 allows for the entry of GABA from the outside to nerve cells, and its sufficient amount can lead to the following effects:
- transmission of information through neurons, suppression of excitation processes;
- transport and absorption of glucose in the brain;
- ensuring cellular respiration and oxidative phosphorylation;
- the combination of certain amino acids and the construction of proteins;
- regulation of protein production in the brain.
[ 8 ]
Pharmacokinetics
The components of the medicinal product Gamalate B6 are mostly represented by physiological substances (GABA, γ-amino-β-hydroxybutyric acid and pyridoxine). Standard methods of studying pharmacokinetic properties in this case are not applicable, due to the impossibility of quantitatively assessing external and internal components. The composition of the drug also does not allow for analysis using a radioactively labeled product, due to the significant radioactive load.
Dosing and administration
Gamalate B6 is used to treat adult patients. The drug is taken orally in the amount of 2 tablets 2-3 times a day.
The duration of the course of therapy may depend on the patient's well-being and the characteristics of the pathology. As a rule, treatment lasts from 2 months to one and a half years.
[ 13 ]
Use Gamalate B6 during pregnancy
Due to insufficient information about the pharmacokinetic properties of the drug, Gamalate B6 can be prescribed to pregnant and lactating women only under the supervision of a medical specialist, and only when the expected benefit from treatment is clearly greater than the probable danger posed to the fetus and the process of gestation.
Contraindications
A contraindication to the administration of Gamalate B6 is individual hypersensitivity to any of the components of the drug.
Side effects Gamalate B6
In some cases, especially if the dosage of the drug is not followed correctly, the following side effects may occur:
- dyspeptic disorders (nausea, vomiting, bowel disturbances);
- manifestations of allergies (skin rash, redness of the skin, itching).
Side effects (except allergies) usually disappear when the dosage of the drug is revised.
Overdose
Gamalate B6 is considered a low-toxic drug. For this reason, the possibility of intoxication with the drug is not considered.
Interactions with other drugs
At the moment there is no description of possible interactions of Gamalate B6 with other drugs.
[ 14 ]
Storage conditions
It is advisable to store the medicine in places inaccessible to children, at a temperature of up to +30°C.
[ 15 ]
Attention!
To simplify the perception of information, this instruction for use of the drug "Gamalate B6" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.