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Gamalate B6
Last reviewed: 23.04.2024
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Medication Gamalate B6 refers to psychostimulating and nootropic drugs that are used in syndromes of excessive activity and attention disorders.
The drug is produced by the Spanish pharmaceutical company Ferrer Internacional.
Gamalate B6 is prescribed for prescription in the pharmacy network.
[1]
Indications of the gamalate B6
Gamalate B6 can be given to adult patients as an adjunct to functional asthenic syndrome, accompanied by the following symptoms:
- emotional instability;
- disorders of memory processes and concentration of attention;
- depressive states;
- a violation of social adaptation.
[2]
Release form
Gamalate B6 is produced in the form of tablets in blisters. One blister contains 10 tablets (in a shell). The cardboard box contains 2 blisters, that is, 20 tablets.
Composition of the medicinal product:
- magnesium glutamate 0.75 g;
- γ-aminobutyric acid 0.75 g;
- γ-amino-β-hydroxybutyric acid 0.37 g;
- pyridoxine hydrochloride 0.37 g.
Pharmacodynamics
The pharmacodynamic properties of Gamalate B6 are represented by the complex action of such components as 4-aminobutanoic acid, amino-β-hydroxybutyric acid and pyridoxine: these substances are simultaneously natural components of the structure of the brain tissues. Medpreparat has a neuro-regulatory effect on the reactions occurring in the brain, and also has a small calming and neurotonic effect.
GABA is formed by the reaction of cleavage of glutamic acid. This process is enhanced by the action of GDK and pyridoxine. The end result is the formation of amino-β-hydroxybutyric acid, which is capable of increasing learning ability and stimulating memory.
In addition, GABA can be re-transformed into an acid, which contributes to the additional supply of oxygen to the brain tissues.
In brain functional disorders, deficiency of inhibition reactions is formed, which is associated with a decrease in the level of GABA, which acts as the main neurotransmitter of the inhibition process. The use of Gamalate B6 allows you to ensure that GABA from the outside gets to the nerve cells, and its sufficient amount can lead to the following effects:
- transmission of information on neurons, suppression of excitation processes;
- transfer and assimilation of glucose in the brain;
- maintenance of cellular respiration and oxidative phosphorylation;
- combining some amino acids and building proteins;
- regulation of protein production in the brain.
[8]
Pharmacokinetics
The components of the drug Gamalate B6 are mostly represented by physiological substances (GABA, γ-amino-β-hydroxybutyric acid and pyridoxine). Standard methods for studying pharmacokinetic properties are inapplicable in this case, in view of the impossibility of quantifying the external and internal components. The composition of the medication also does not make it possible to carry out the analysis using radiolabeled product, due to a significant radionavigation.
Dosing and administration
Gamalate B6 is used to treat adult patients. The drug is taken orally in the amount of 2 tablets 2-3 times a day.
The length of the course of therapy may depend on the patient's well-being and pathology. As a rule, treatment lasts from 2 months to one and a half years.
[13]
Use of the gamalate B6 during pregnancy
Due to insufficient information about the pharmacokinetic properties of the drug, the prescription of Gamalate B6 for pregnant and lactating women is allowed only under the supervision of a medical specialist, and only when the expected benefit from the treatment is certainly greater than the likely danger posed to the fetus and the gestation process.
Contraindications
Contraindication to the appointment of Gamalate B6 is the individual hypersensitivity to any of the constituent medications.
Side effects of the gamalate B6
In some cases, especially if the dosing of the drug is incorrectly observed, the following side effects may occur:
- Dyspeptic disorders (attacks of nausea, vomiting, stool disorders);
- manifestations of allergies (skin rash, redness of the skin, itching).
Side-effects (except for allergies), usually go through a revision of the dosing of the drug.
Overdose
Gamalate B6 is considered a low-toxic drug. For this reason, the possibility of drug intoxication is not considered.
Interactions with other drugs
At the moment, there is no description of the possible interactions of Gamalate B6 with other drugs.
[14]
Storage conditions
The medication should be stored in places inaccessible to children, at t ° up to + 30 ° C.
[15]
Attention!
To simplify the perception of information, this instruction for use of the drug "Gamalate B6" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.