GA-40

Cancer is one of the most common diseases of our time. Almost every family has at least one member who suffered from this disease. The specific causes of this disease have not been identified, but an incredible number of factors have been found that contribute to its formation, including the environment, bad habits, food consumed and, of course, heredity. There is no medicine that gets rid of cancer, but there are drugs that increase the body's resistance to the formation of cancer cells. One of these drugs is GA-40.

[ 1 ]

Indications GA-40

The drug GA-40 is used in complex therapeutic treatment for:

• treatment of malignant tumors, both in the preoperative and postoperative periods, as well as during the use of chemotherapy;
• treatment of blood diseases - leukemia, namely myeloblastic and megakaryoblastic;
• treatment of benign tumors, namely myomas, cystoses, adenomas, fibroids, etc.;
• treatment of allergic bronchitis and asthma;
• treatment of infectious diseases such as hepatitis (A, B, C), tuberculosis, prostatitis and sexually transmitted diseases (mycoplasmosis, ureaplasmosis, trichomoniasis, chlamydia, toxoplasmosis);
• prevention of neoplasms (in high-risk patients).

[ 2 ], [ 3 ], [ 4 ]

Release form

The drug GA-40 is available in cardboard packages, which contain 5 vials with lyophilized substance intended for dissolution with water for injection. One vial contains 1 mg of the active substance - a complex plant polypeptide, an extract from the plant Solomon's seal. The auxiliary substances are: potassium dihydrogen phosphate and sodium chloride.

[ 5 ], [ 6 ]

Pharmacodynamics

The drug GA-40 has the property of slowing down the reproduction of tumor cells. Its action is also aimed at correcting the human immune system, namely humoral and cellular immunity. The drug regulates the formation of leukocytes, normalizing it, and also promotes the correct ratio of T and B cells of the immune system. The antitumor effect is provided by stimulating the body's drug to form an increased amount of cytokines, immunoglobulins, interferons and antitumor factor. At the same time, unlike chemotherapeutic drugs, the drug GA-40 acts only on damaged cells, without affecting normal ones.

When using the drug GA-40, normalization of many indicators is observed in the blood, such as ESR, the number of leukocytes, blood glucose, creatinine, bilirubin, urea, liver enzymes, and minerals.

The drug GA-40 reduces the negative impact of chemotherapeutic drugs, while increasing their therapeutic effect. Improves blood microcirculation and promotes rapid removal of toxic waste products of chemotherapy from the body. Prevents the formation of metastases in organs by reducing the expression of tumor cell adhesion molecules.

[ 7 ], [ 8 ], [ 9 ], [ 10 ], [ 11 ], [ 12 ], [ 13 ], [ 14 ], [ 15 ]

Pharmacokinetics

It is impossible to conduct a pharmacokinetic study of the drug due to the low content of amino acids in human plasma.

[ 16 ], [ 17 ], [ 18 ], [ 19 ], [ 20 ], [ 21 ], [ 22 ], [ 23 ], [ 24 ], [ 25 ]

Dosing and administration

The drug GA-40 is administered intramuscularly or subcutaneously using an insulin syringe. To do this, take a vial with lyophilized substance and dilute it with water for injection (5 ml). To do this, you need to release the rubber cap and inject the liquid into the vial with a needle, then shake it thoroughly.

The dosage is calculated individually depending on the patient's weight, and it is 0.01 ml / kg of weight. For an accurate and correct calculation, it is convenient to use the scale of the insulin syringe, on which the patient's weight is indicated on the left, and the dosage in micrograms on the right. The course of treatment is 21 days. One injection should be administered per day. It is best to use the drug after 18:00 and preferably at the same time. After the end of the course, it can be repeated after one or two weeks if desired. The interval between courses should be at least 3 days and no more than 14. Depending on the complexity of the disease and its stage, it is recommended to conduct from three to ten courses. As a preventive measure against the degeneration of benign tumors into malignant ones, it is recommended to conduct two or three courses per year.

[ 33 ], [ 34 ]

Use GA-40 during pregnancy

The drug is not recommended for use during pregnancy and breastfeeding, as no studies have been conducted on this population group.

Contraindications

There are no specific contraindications to the use of the drug. However, it should not be used by pregnant women, breastfeeding women, children under three years of age, or patients with an allergic reaction to one of the components of the drug.

[ 26 ], [ 27 ], [ 28 ], [ 29 ], [ 30 ]

Side effects GA-40

The only possible side effects are allergic reactions in the form of urticaria or Quincke's edema.

[ 31 ], [ 32 ]

Overdose

There have been no reported cases of overdose with GA-40.

[ 35 ], [ 36 ]

Interactions with other drugs

No interactions with other drugs in complex therapeutic treatment were found. On the contrary, a positive effect on the removal of toxic waste products from the blood of patients was noted.

[ 37 ], [ 38 ], [ 39 ], [ 40 ], [ 41 ], [ 42 ]

Storage conditions

The drug should be stored in the refrigerator at a temperature of +4-10 degrees. The shelf life of an unopened lyophilized substance is 12 months. Diluted with sterile water for injection, the drug should be stored on the upper side shelf of the refrigerator for no more than 60 days. At room temperature, the drug should be stored for no more than 14 days.

[ 43 ], [ 44 ], [ 45 ], [ 46 ]

Shelf life

The manufacturing date and expiration date are indicated on the packaging and are 1 year. It is strictly forbidden to use the drug after the expiration date.

[ 47 ], [ 48 ]