Flebodia 600.

Phlebodia (Phlebodia) is a drug that is used for the treatment and prevention of various vascular diseases, mainly related to venous insufficiency and impaired blood circulation in the veins.

The main active ingredient of phlebodia is diosmin. Diosmin belongs to the group of bioflavonoids, which improve blood microcirculation, strengthen vessel walls and reduce their permeability, which helps to reduce swelling and inflammation.

Phlebodia is used in the following cases:

1. Chronic venous insufficiency: The drug helps to improve blood circulation in the veins and reduce swelling and soreness in the legs.
2. Hemorrhoids: Phlebodia may help reduce hemorrhoid symptoms such as itching, pain, and swelling.
3. Prevention of venous thrombosis: In some cases, the drug may be used to prevent blood clots in the veins.

Phlebodia is usually available in the form of oral tablets. The dosage and regimen are determined by the doctor depending on the patient's condition and the severity of the disease.

It is important to note that the use of phlebodia should be carried out only on the prescription of a doctor. Before starting to take this drug, it is recommended to consult with a medical specialist.

Indications Flebodia 600.

Phlebodia is commonly used for the treatment and prevention of various vascular diseases based on venous insufficiency and impaired blood circulation in the veins. Here are the main indications for the use of Flebodia:

1. Chronic venous insufficiency: This condition is characterized by impaired function of the venous valves, resulting in swelling, pain, fatigue and other symptoms in the legs. Phlebodia helps improve blood microcirculation, strengthen blood vessel walls and reduce swelling and inflammation.
2. Varicose Veins: Flebodia helps reduce the swelling and pain associated with varicose veins and improves the quality of life for patients with this condition.
3. Phlebologic complications in pregnancy: The drug may be prescribed to improve venous blood flow in pregnant women with symptoms of varicose veins and other manifestations of venous insufficiency.
4. Postthrombotic Syndrome: Phlebodia may be used to treat symptoms of postthrombotic syndrome, such as swelling, soreness, and heaviness in the legs after suffering deep vein thrombosis.
5. Prevention of thromboembolic complications: The drug is sometimes prescribed as a prophylactic agent to prevent the development of thrombosis and thromboembolism in patients at increased risk of these complications.

Release form

Flebodia is available in tablet form, with a dosage of 600 mg, which provides convenience for patients.

Pharmacodynamics

The pharmacodynamics of Flebodia is mainly related to its active component - diosmin. Diosmin belongs to the group of bioflavonoids, which has the following pharmacological properties:

1. Improving blood microcirculation: Diosmin helps to improve blood microcirculation in blood vessels, reducing blood stasis and improving blood supply to tissues.
2. Strengthening of vessel walls: Diosmin strengthens and thickens the walls of veins, reducing their permeability and increasing their resistance to stretching.
3. Anti-inflammatory effects: Phlebodia has anti-inflammatory effects that help reduce inflammation and swelling in blood vessels.
4. Antioxidant Action: As a bioflavonoid, diosmin has antioxidant properties, protecting cells from the harmful effects of free radicals.
5. Improving Lymphatic Drainage: Diosmin helps improve lymphatic drainage, which helps reduce swelling and improve tissue metabolism.

Pharmacokinetics

The pharmacokinetics of Flebodia are still not fully developed. However, available information indicates the following features:

1. Absorption: Diosmin, the main active ingredient of Flebodia, has good bioavailability after oral administration. After taking Flebodia, the tablets are usually completely absorbed from the gastrointestinal tract.
2. Metabolism: Diosmin is metabolized in the liver to form the active metabolite - hydroxyethylrutin (diosminic acid). This metabolite has biological activity and is also able to improve microcirculation and stabilize intravascular permeability.
3. Excretion: Hydroxyethylrutin and other metabolites of diosmin are excreted mainly by the kidneys as metabolites and partially through the intestine.
4. Half-life: The half-life of hydroxyethylrutin is about 11 hours.
5. Accumulation: When taking Flebodia regularly, accumulation of diosmin and its metabolites in the body is not observed due to their intensive metabolization and elimination from the body.

Dosing and administration

The dosage and method of administration of Phlebodia (Phlebodia) is usually determined individually by a doctor depending on the nature and severity of the disease. Here are the general recommendations for use:

1. For adults:

• The usual recommended dose of Flebodia is 1 tablet (600 mg diosmin) per day.
• The tablet is best taken in the morning, half an hour before a meal, with plenty of water.
• The duration of treatment is usually determined by the doctor and depends on the nature and severity of the disease.

2. For pregnant women:

• The dosage of Flebodia for pregnant women may vary depending on the condition and severity of venous problems.
• It is usually recommended to start with a low dose, such as 1 tablet (600 mg) per day, and then depending on the effectiveness of the treatment and the patient's condition, the doctor may adjust the dosage.
• The duration of intake is also determined by the doctor and may vary depending on the nature of the disease and its dynamics.

3. For the kids:

• The use of Flebodia in children is rarely prescribed and should only be administered as prescribed by a physician.
• Dosage and mode of administration in children are determined individually depending on age, weight and nature of the disease.

Use Flebodia 600. during pregnancy

The use of Phlebodia during pregnancy may be considered by a doctor if it is necessary to treat vascular problems. It is important to note that the safety of using Phlebodia during pregnancy has not been fully established and the decision to use it should be made with caution and only after consultation with a doctor.

In some countries, Flebodia may be used to treat varicose veins and other vascular diseases in pregnant women. Its action is aimed at improving blood microcirculation and reducing edema, which may relieve symptoms of venous insufficiency.

However, despite some positive data regarding the safety of using Flebodia during pregnancy, it is still recommended to take the drug only when prescribed by a doctor and in accordance with his recommendations.

If a pregnant woman has vascular problems, she should discuss with her doctor all the possible risks and benefits of Flebodia in her particular situation. The doctor will evaluate the indication, taking into account the health status of the mother and fetus, as well as other risk factors and contraindications.

Contraindications

Contraindications to the use of Flebodia may vary depending on the specific clinical situation and individual patient characteristics. However, contraindications usually include the following conditions:

1. Individual intolerance: The drug may cause an allergic reaction in some patients. Therefore, if the patient has had allergic reactions to diosmin or other components of Flebodia, its use is contraindicated.
2. Pregnancy and breastfeeding: Although Flebodia is widely used for the treatment of varicose veins and other vascular diseases in pregnant and breastfeeding women, some studies show that the safety of the drug use during pregnancy and breastfeeding may not be fully established. Therefore, the use of Flebodia during these periods requires special attention and consultation with a doctor.
3. Acute thrombophlebitis and thromboembolism: The use of Flebodia may be undesirable in acute thrombophlebitis or thromboembolism, as the drug may promote blood thinning and increase bleeding.
4. Pediatric age: Data on safety and efficacy of Flebodia in children are not fully established. Therefore, the use of the drug in children should be carried out only under the prescription of a doctor.

Side effects Flebodia 600.

Flebodia is usually well tolerated by patients, but some people may experience side effects. Here are some of the possible side effects of Flebodia:

1. GI Disorders: In some cases, patients may experience dyspeptic, such as nausea, vomiting, diarrhea, or abdominal discomfort.
2. Allergic Reactions: Some people may experience allergic reactions such as skin rash, itching or angioedema. In rare cases, anaphylactic reactions may develop that require immediate medical attention.
3. Headache and dizziness: Some patients may experience headaches or dizziness while taking the drug.
4. Abdominal pain and back pain: These symptoms may occur in some patients.
5. Drowsiness: Some people may feel drowsy or tired while taking Flebodia.
6. Other rare adverse reactions: Other rare adverse reactions such as increased blood pressure, increased chest pain, or insomnia may occur in isolated cases.

Overdose

Information on Flebodia overdose is limited, and overdose cases are usually rare due to the low toxicity of the drug. However, if a higher dose than recommended is taken or symptoms indicating an overdose occur, medical attention should be sought or a healthcare provider should be contacted immediately.

Symptoms of a Flebodia overdose may include an increase in typical side effects such as GI disorders (nausea, vomiting, diarrhea), dizziness, headache, and possibly an increase in allergic reactions.

Treatment of Phlebodia overdose is usually symptomatic. The doctor may recommend gastric lavage, intake of activated charcoal and symptomatic therapy depending on the symptoms.

Interactions with other drugs

The interactions of Phlebodia (Phlebodia) with other drugs remain limited, and basic information on interactions is provided only in some studies and klinical Pharmacokinetics. Nevertheless, the following should be taken into account:

1. Anticoagulants: Flebodia may increase the effect of anticoagulants (drugs that reduce blood clotting) such as warfarin. Patients taking anticoagulants should be closely monitored for signs of bleeding or clotting disorders when taking Flebodia at the same time.
2. Drugs metabolized by cytochrome P450: Phlebodia may affect the metabolism of some drugs metabolized by cytochrome P450 enzymes in the liver. This may lead to changes in the concentration of these drugs in the blood. Therefore, when taking Flebodia concomitantly with such drugs, careful monitoring and possibly dosage adjustment is recommended.
3. Flavonoid-enhancing drugs: Phlebodia may enhance the effect of other drugs containing flavonoids, which may lead to an increase in their effect or adverse reactions.

Storage conditions

Phlebodia should be stored according to the manufacturer's instructions and your doctor's recommendations. The following is generally recommended:

1. Storage Temperature: Phlebodia should be stored at room temperature not exceeding 25°C.
2. Storage conditions: The drug should be stored in a place protected from light and moisture to prevent decomposition of active ingredients.
3. Packaging: After opening the package, the tablets should be stored in a blister or dark container with a tightly closed lid.
4. Children's access: Like any other medication, Flebodia should be stored out of reach of children to prevent accidental use.

Shelf life

Be sure to follow the manufacturer's instructions regarding the expiration date of the drug. Do not use Flebodia after the expiration date indicated on the package.