Flavoside

Flavoside has a direct antiviral and antioxidant effect. The drug protects and stabilizes the local immune activity of the mucous membranes of the upper respiratory tract, increasing the values of lactoferrin and excretory immunoglobulin A.

The flavonoids contained in the drug can suppress the replication of RNA and DNA of the following viruses: chickenpox, common herpes of type 1-2, EBV, and besides this, papillomavirus and CMV.

Indications Flavoside

It is used for such diseases:

• infections associated with herpes simplex (type 1-2), as well as neonatal herpes;
• herpes type 3 (herpes zoster);
• infectious form of mononucleosis , which develops due to EBV (active or chronic stage);
• lesions appearing under the influence of CMV;
• chickenpox ;
• in combination therapy for HIV or AIDS, and in addition, for hepatitis types B and C;
• prevention and therapy of influenza types A or B, and in addition with ARVI and pandemic strains.

Release form

The release of the medication is realized in the form of a syrup, inside glass bottles with a capacity of 60, 100 or 200 ml; inside a pack of 1 such a bottle and a measuring cup.

Pharmacodynamics

Antiviral activity develops when the specific enzymes of the virus slow down: thymidine kinase with reverse transcriptase, as well as DNA polymerase.

The principle of the direct anti-influenza effect of drugs is associated with the ability to slow down the neuraminidase action and RNA binding, and, in addition, to induce the binding of internal interferon.

Exposure to Flavoside leads to the development of dose-related binding of internal α- as well as γ-interferons to normal, physiologically active values, and at the same time increases nonspecific resistance against bacterial and viral infections. Long-term daily intake does not lead to the appearance of refractoriness of immunity: there is no suppression of the activity of α- and γ-interferons, stabilization of immune activity is noted. Thanks to this, long-term treatment can be carried out for chronic and recurrent infections.

When taken once orally, interferon actively binds within a period of 6 days, with the maximum values observed on the 2nd day.

The antioxidant effect of drugs develops when the accumulation of elements of lipid peroxidation is prevented and the course of free radical processes slows down. As a result, the cellular antioxidant status is potentiated and poisoning is weakened, which helps to adapt to negative external factors and accelerates the body's recovery after infection.

The drug is a modulator of apoptosis, potentiating the activity of apoptosis-inducing ligaments; it helps to accelerate the excretion of cells infected with the virus, and prevents the development of chronic pathologies during latent viral infection.

Dosing and administration

It is necessary to apply the syrup approximately 20-30 minutes before eating; the syrup bottle must first be shaken, and then measured out the required portion in a measuring glass.

The standard therapeutic regimen for herpes infection, hepatitis types B, C, as well as chickenpox, HIV and AIDS.

For 1 month, you need to use the daily dosage, which is divided into 2 applications:

• for persons under 1 years of age - 1 ml;
• a child of 1-2 years old - 2 ml;
• a child of 2-4 years old - during the 1-3 days of treatment, 3 ml, and then (from the 4th day) - 6 ml;
• age group 4-6 years - during the 1-3 day, 6 ml, and then 8 ml;
• age 6-9 years - for 1-3 days, take 8 ml, and then 10 ml;
• children 9-12 years old - 10 ml for 1-3 days, and then 12 ml;
• adolescents and adults - 10 ml each in the period 1-3 days, and later 16 ml.

In the case of an infectious form of mononucleosis, CMV and herpes zoster.

Serving size follows the standard treatment regimen, and the duration of therapy is extended to 3 months. At the same time, after the main cycle is completed, supportive treatment is carried out (2-4 months), with the intake of half the daily dosage, which is taken from the 4th day of standard therapy.

During combined treatment for HIV, AIDS and hepatitis B and C.

The size of the dose corresponds to the standard scheme, and the duration is increased to 4-6 months.

When treating and preventing the development of pandemic strains, influenza types A, B, as well as ARVI.

For prevention, the medication is consumed within 0.5-1.5 months (especially during an epidemic or with severe morbidity).

Treatment lasts 0.5 months, but with complications of bacterial origin, it can increase up to 1 month.

Daily dosages correspond to those indicated in the standard regimen; with prevention, use half a portion 1 time per day.

• Application for children

Flavoside is allowed to be used in pediatrics from birth as it is considered safe for children.

Use Flavoside during pregnancy

When performing preclinical tests, there was no development of carcinogenic, embryotoxic, teratogenic or mutagenic effects. But it is necessary to prescribe the drug with hepatitis B or pregnancy very carefully.

Contraindications

The main contraindications:

• signs of severe intolerance to the elements of the medication;
• exacerbation of ulcerative lesions in the gastrointestinal tract;
• diseases of the autoimmune type.

Side effects Flavoside

Among the side symptoms:

• disruption of the gastrointestinal tract in the form of nausea, epigastric pain, diarrhea and vomiting (with the development of signs of dyspepsia, syrup should be consumed after 90-120 minutes after eating);
• possibly a transient rise in temperature up to 38 ° C during the 3rd-10th day of treatment;
• in the treatment of viral hepatitis in patients with severe cytolysis syndrome, there may be an increase in aminotransferase activity or, less often, bilirubin values;
• active phase of chronic gastroduodenitis or the development of GERD;
• headache;
• rarely, there are signs of allergy in the form of an erythematous rash.

Overdose

There is a likelihood of more severe side symptoms, especially those related to the function of the gastrointestinal tract.

Interaction with other drugs

During the treatment of viral, bacterial or viral-fungal pathologies, Flavoside should be combined with antimycotics and antibiotics.

Storage conditions

Flavoside must be stored in a place protected from sunlight. It is forbidden to freeze syrup. Temperature indicators - no higher than + 25 ° С.

Shelf life

Flavoside can be used within a 24-month term from the date of manufacture of the therapeutic. The shelf life of the bottle after opening is a maximum of 1 month.

Analogs

The analogs of the drug are the substances Arbidol, Amizon, Imustat with Arbivir, Altabor and Arpeflu with Virelakir, as well as Sovaldi and Grateziano.

Reviews

Flavoside has received a lot of positive reviews. High efficiency, quality of the drug and ease of use are noted.

Among the disadvantages of the drug, there is a long duration of therapy, the presence of E-elements in its composition, as well as a high cost.