, medical expert
Last reviewed: 23.04.2024

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Fenistil is a medicine that blocks the activity of H1-receptors of histamine.

trusted-source[1], [2], [3], [4]

Indications Fenistila

It is used (in oral form) for the treatment of the following disorders:

  • allergic symptoms - hives, hay fever and allergic rhinitis that occurs all year round, and besides allergies to food and medicine, as well as Quincke's edema;
  • epidermal itching, having a different nature - against eczema, measles, various dermatoses, rubella and atopic dermatitis, and in addition caused by chickenpox (the gel can be used to treat chickenpox in a child) or insect bites;
  • to prevent the occurrence of allergic symptoms on the background of the implementation of hyposensitizing procedures.

Emulsion with gel can be used in the following pathologies:

  • skin-affecting itching, having a different etiology (eczema, dermatoses, insect bites or urticaria), except when the cause is cholestasis;
  • various burns (household, solar, etc.).

Fenistil Penzivir is used in the usual herpes of a recurrent nature, which often develops on the lips.

Release form

The release of the drug is carried out in orally administered drops and tablets, and in addition in the form of an emulsion and gel.

Drops are produced in a volume of 20 ml bottles with a dropper.

Gel for external processing is realized in tubes with a capacity of 30 or 50 g.

The emulsion for external use is produced in flacons having a capacity of 8 ml, and similar in shape to a roller pencil.

Tablets are called Fenistil 24.

Fenistil pencivir

Fenistil pencivir is a 1% cream for local treatment with a toning effect. It is produced in tubes with a capacity of 2 or 5 g.


The active element of the drug is a competitive histamine antagonist. The drug has anti-allergic, antipruritic properties, it helps to strengthen the strength of weakened capillaries, which lead to the development of allergic symptoms in a person. This is the reason for the frequent use of Fenistil for allergies. In addition, the drug found mild anticholinergic, and in addition anti-bradykinin effect. When using drops of drugs in the daytime interval, there may be a weak sedative effect.

The gel or emulsion applied to the epidermis helps to reduce the intensity of irritation and itching caused by allergies, and at the same time have a local anesthetic effect. Emulsion helps to cool, moisturize and soften the epidermal layer.

Fenistil pencivir is an antiviral agent with pronounced activity against common herpes viruses (type 1 and type 2), VEB, CMV and chickenpox virus.

The medicine helps to block the processes of viral reproduction (this virus remains in the body of a large number of people for a long time, while remaining inactive). Catalysts for the activation of the processes of its reproduction are such factors as acute respiratory disease, CFS or cold. As a result, fever develops, which manifests itself as a bubble-shaped rash on the lips, as well as on the area around them.

Thanks to the use of the cream, the healing process is accelerated, the pain intensity is reduced and the probability of transmission of infection is reduced.



After ingestion, the active ingredient Fenistila at high speed and almost completely absorbed. Peak indicators are recorded after 2 hours from the time of reception. The bioavailability values are about 70%. The drug without complications passes into the tissues.

Exchange processes occur in the liver - with the help of methoxylation with hydroxylation.

The half-life is approximately 6 hours. Excretion - with bile, as well as urine (only 10% of the drug is excreted unchanged, and the remaining 90% - in the form of decay products).

With local external treatment, the medication easily penetrates the epidermis, and the level of its total bioavailability is 10%. The medicine begins to act after a few minutes after the treatment of the skin.


Dosing and administration

Scheme of use of medicinal drops.

Take the drops inside. The sizes of portions for an adult and adolescents older than 12 years taken per day are 3-6 mg (or 60-120 drops), which are divided into 3 equal dose doses. People with a strong predilection for drowsiness need to consume 20 drops of drugs during the first half of the day, as well as 40 drops of the drug before going to bed.

Breastfed babies at the age of 1-12 months are used drugs in a dose of 3-10 drops with a triple take for a day. A child of 1-3 years is recommended a three-time intake of 10-15 drops per day. Patients of the age group 3-12 years should use 3 times a day for 15-20 drops of the drug.

If required, the drops can be added to the bottle with infant formula for feeding.

Ways of using the gel.

It is necessary to apply the gel externally - to the places that were affected by the disease. For a day there are 2-4 such procedures. With a high intensity of irritation or pruritus, and besides this, with common forms of lesions of the epidermis, the doctor can recommend the use of the gel in combination with drops of Fenistil or another oral form of drugs.

During gel treatment, UV light should be avoided in areas previously treated with the drug. Because of this, it is desirable to abandon a prolonged stay under the sun's rays.

The same scheme is used in the treatment of children. Gel can also be used in newborns, but only after preliminary discussion of this matter with the doctor and under his supervision.

Mode of use of drug emulsion.

It is prescribed for external use - with the help of a pencil roller it is applied to the skin 2-4 times / day (the multiplicity depends on the medical prescriptions). Emulsion can be used in children.

The scheme of reception of the tablet form of the preparation.

Tablets can not be taken by persons under 12 years of age.

Usually a day should be consumed 1-nu tablet, because the drug's drug exposure lasts 24 hours. It is recommended to eat it in the evening so that you do not feel drowsy. Swallow the capsule wholly, while washing with plain water.

The duration of such a treatment cycle can be a maximum of 25 days.

Use of Fenistil Pentsivir cream.

To treat affected herpes epidermis or mucous, you need to squeeze a little cream on a finger or cotton swab, then apply it to the desired area. This procedure should be repeated at intervals of 2 hours, no more than 7-8 times / day in the period of 4 days.

Start the use of the drug is desirable immediately after the onset of the first symptoms of infection. Also, it is required to adhere to the duration of the therapeutic period specified in the instruction, even if the symptoms of the disease have disappeared after 2 days of therapy.

To process with a cream it is necessary only those zones on lips and area around of a mouth on which there was a herpes. It is forbidden to apply it to oral or nasal mucous membranes, ocular membranes and genitals.

People who have weakened immunity should first consult a doctor.

If the improvement does not occur after 4 days of therapy, or the condition even worsened, it is recommended to consult with a specialist.



Use Fenistila during pregnancy

It is forbidden to use gel and drops of the drug on the 1st trimester. In the 2nd and 3rd trimesters, these medicinal forms of Fenistil can be administered exclusively in the presence of life indications, and taken under the constant supervision of the doctor. It is forbidden to process large areas of the epidermis with gel.

Do not use medicine during lactation. It is strictly forbidden to gel the nipple region.


Among the contraindications:

  • glaucoma, which has a closed-angle form, as well as asthma;
  • hyperplasia in the prostate;
  • presence of intolerance in relation to medicamentous components.

Caution is required when used in persons with pulmonary diseases, having a chronic degree and having an obstructive character.

Before using the drug it is always necessary to consult your doctor.

Side effects Fenistila

The use of a drug may provoke the occurrence of some side effects:

  • disorders affecting the NS: the symptoms of excitation or drowsiness (most often observed in the first days of therapy), as well as headaches or dizziness;
  • disorders of digestive activity: nausea or dryness of the oral mucosa;
  • problems with respiratory function: disorders of external respiration and dryness in the pharynx;
  • Other signs: rashes, swelling and muscle spasms.

The use of Fenistil pencivir cream can lead to the appearance of sensations of numbness, burning or tingling at the treatment sites.



When you use drugs inside, you must strictly observe the indicated dosage, because there is a high probability of intoxication. Because of this, suppression of the central nervous system may occur or develop severe drowsiness (in an adult). It is also possible to stimulate the activity of the central nervous system and the development of m-holinoblokiruyuschimi symptoms (usually occur in children), among them a feeling of excitement, mydriasis, dry mouth mucosa, tachycardia, convulsions with hot flushes, ataxia, febrile condition and hallucinations. In addition to this list, the development of collapse, delayed urination and lowering blood pressure.

When poisoning with Fenistil it is required to give the affected person an activated charcoal and a laxative drug of saline type. Also, in order to eliminate the effects of overdose, measures are taken to maintain respiratory and CAS activities.

Interactions with other drugs

The effect of the drug potentiates the effect exerted on the body by anxiolytics and hypnotics.

When combined with ethyl alcohol, inhibition of psychomotor manifestations is noted.

The combination of Fenistil with MAOI potentiates the cholotropic effect, and in addition the overwhelming influence exerted on the CNS.

The combination of m-cholinoblockers with tricyclics leads to an increase in the probability of an increase in IOP values.

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Storage conditions

Fenistil is required to be kept out of the reach of small children. The temperature level for all therapeutic forms, except for the cream - a maximum of 30 ° C. Cream Fenistil Pencivir should be stored at temperature levels not above 25 ° C and should not be frozen.

Shelf life

Fenistil is allowed to be applied within 36 months from the date of manufacture of the drug.


Application for children

Drops can not be administered to babies under the age of 1. For older children, it is important to carefully observe the dosage prescribed by the doctor. Prescribe Fenistila drops to children carefully, because there is a possibility of developing a nighttime apnea.

The gel form of drugs can be prescribed for children of any age, but it is recommended to apply it under the supervision of a pediatrician.

Fenistil pentivir can be used in children over 12 years of age.



Among the cheaper analogues of the gel is Zetrin with Vibrocil. In addition, antiallergenic medicines are given among similar medicines - Claritin with Tavegil, Diazolin with Loratadin and so on.

Fenistil Penzivir has such analogues as Virolex, Zovirax, Acic with Gerpevir, and besides this, Atsivir, Vartek, Herpetad with Acyclovir, Medovir with Herpferon, and Provirsan with Agerp.


Fenistil is considered a very effective remedy, helping to eliminate allergic symptoms.

Often, positive feedback about the effect of drops leaves parents who used the medicine for their children (including newborns). In these comments, it is noted that, thanks to drops, rashes and itching with irritation quickly disappear.

Opinions about the gel used in children, suggest that it helps well with the bites of various insects, and in addition to rashes and other allergic symptoms. In the reviews about the helium form of LS, used by the newborn, they write that the gel helps to quickly remove redness and skin irritation. Based on the messages on the forums, the gel is often used for treatment in infants.

Comments about the drug emulsion are more rare, but they also indicate the convenience in using drugs and its high efficiency.

At times, negative comments also appear, which indicate that the medication did not have the desired effect. But usually in such situations we are talking about lesions, the cause of which is not an allergy.


To simplify the perception of information, this instruction for use of the drug "Fenistil" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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