Medical expert of the article
New publications
Preparations
Fébièle
Last reviewed: 23.04.2024
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
The active ingredient of this medicine is produced from the rhizomes of turmeric (fenipentol) and has the ability
Activate:
- the process of bile secretion and the concentration of bile acids in it,
- transformation of inactive pancreatic prolipases into active enzymes that catalyze the processes of lipid cleavage previously emulsified by hepatic bile.
In addition, the drug stimulates the production of gastric mucus.
Indications of the febihola
The drug is used for the following chronic secretory disorders of the digestive organs:
- violation of the exocrine function of the liver and pancreas;
- dysfunction of the biliary tract and its anomalies, accompanied by congestion of bile;
- cholecystitis, cholangitis and their combined form;
- postcholecystectomy syndrome;
- motorotonic dysfunction of the gallbladder, ducts and sphincters;
- hypoacid gastritis;
- dyspeptic manifestations.
Release form
Capsules containing 100mg of phenypentol, and also - auxiliary substances: 85% glycerin, dietary supplement - chlorophyllin (eucalyptus leaf extract, fructose, ascorbic acid), preservative and antiseptic - methylparaben, gelatin.
Pharmacodynamics
The active ingredient Febichola has a choleretic effect, while increasing the concentration of dense components - cholesterol and bile acids, which, in turn, increase the enzymatic activity of pancreatic lipase. This contributes to the normalization of the cleavage and assimilation of fats, ingested with food into the digestive canal. The action of the drug occurs by raising the level of the peptide hormone secretin in the blood. This increases the production and volume of pancreatic (pancreatic) juice, the content of bicarbonates and active lipases in it.
In addition, phenylpentol binds free radicals in liver tissues, which blocks the process of oxidative degradation of lipids and protects hepatocytes from damage.
The active ingredient activates the work of the gastric glands, increasing the production of gastric mucus (mucin), enveloping and protecting the mucous membrane of the stomach.
He also exhibits moderate prophylactic activity against the formation of gallstones and ducts, reducing the absolute quantitative measure of the cholesterol content in bile.
Pharmacokinetics
The maximum effect from the action of phenylpentol is reached after a quarter of an hour after administration. The main part of the drug is broken down by the liver and enters the portal circle of blood circulation. In cells of tissues, it concentrates slightly. With urine in the form of a metabolite, up to 35% of the active ingredient is excreted, in the same way - less than 1% in unchanged form.
Dosing and administration
The drug is dosed on two capsules, the frequency of reception is prescribed by the doctor. It varies from a single dose of two capsules at once to three doses per day of the same single dose. Capsules are swallowed whole and washed down with a glass of water to prevent their adherence in the esophagus. The standard duration of treatment is three weeks.
[2]
Use of the febihola during pregnancy
It is not recommended for pregnant and lactating women.
Contraindications
Do not appoint an age group of patients 0-14 years, pregnant women and nursing mothers, as well as acute forms of inflammatory diseases of the liver, pancreas and gallbladder and their complications, for example, empyema of the gallbladder, obstruction of the biliary tract.
[1]
Side effects of the febihola
The preparation is characterized by good tolerability, however, in rare cases, skin allergic reactions can be observed, the heaviness in epigastrium, swelling, heartburn, nausea can be felt.
Overdose
Not fixed.
Storage conditions
Store in accordance with the temperature range from 10 ℃ to 25 ℃. Keep away from children.
[5]
Shelf life
3 years.
Attention!
To simplify the perception of information, this instruction for use of the drug "Fébièle" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.