Despite all the above-described points, doctors continue to use "Eufillin" in chronic bronchitis with obstruction of the airways, bronchospasm, emphysema and other dangerous conditions, when the drug almost saves lives.
Consider how different forms of the drug can be used to treat chronic inflammation of the bronchi.
Tablets "Eufillin" with bronchitis
The drug in the form of tablets is intended for oral administration. Take medicine after eating, drinking ½ cup of water. Tablets can be swallowed whole or broken into 2-4 parts.
The dosage of the drug is selected individually, taking into account the rate of excretion of the drug from the body in different groups of patients.
The daily dose of the drug for adults and adolescents with a body weight of more than 50 kg ranges between 450-900 mg (3 to 6 tablets 150 mg) with the possibility of increasing the dose to 8 tablets. Take medication every 6 hours, dividing the daily dosage into 3-4 equal parts.
If the weight of an adult patient is in the range of 40-50 kg (for adolescents, this figure is slightly higher - from 45 to 55 kg), the daily dose of the medicine should not exceed 600 mg.
The daily dose for children over 6 years and adolescents with a body weight of less than 45 kg is calculated as 13 mg per kilogram of body weight of the patient. In general, this results in a minimum daily intake for adults - 450 mg (3 tablets). Multiplicity of admission - 3 times a day.
Ampoules "Eufillin" with bronchitis
Pharmacological industry produces "Eufillin" not only in the form of tablets, but also in the form of a solution of the drug, placed in ampoules. Each ampoule (5 and 10 ml) of the drug contains 120 or 240 mg of aminophylline.
"Eufillin" with bronchitis in injections can be prescribed both intravenously and intramuscularly. Intravenous injections are indicated if the situation is life-threatening and urgent care is required. After all, with this method of administration, the drug most quickly enters the bloodstream, forming effective concentrations there.
For intravenous injections, the drug is mixed with a 9% solution of sodium chloride in a ratio of 1: 2. The duration of the injection should not be less than 5 minutes, otherwise there is a high probability of adverse reactions from the cardiovascular system (increased heart rate, shortness of breath, falling blood pressure). If this is observed even at a low injection rate of the drug, you need to go to a drip introduction.
During the injection, the patient should be in a supine position, and the doctor must constantly monitor his condition. The dose for adults is calculated as 6 mg per 1 kg of body weight.
Intramuscularly, the drug can be administered to a child according to vital indications. In this case, the dose is calculated as 15 mg of aminophylline per kilogram of patient weight.
If necessary, the dosage of 1 time in 2-3 days can be increased by a quarter of the initial dose.
The dropper "Efillina" with bronchitis can be prescribed for adults and children, if the situation arises threatens the patient's life.
In situations that pose a threat to the patient's life, the drug is given in a shock dose (5.6 mg per 1 kg of body weight) for 30 minutes, maintenance therapy is performed in smaller doses (0.9-3.3 mg per 1 kg of weight at a rate of 30-50 drops per minute up to 3 times a day).
Solution for infusion is prepared by mixing 2 ampoules of "Eufillina" in 5 or 10 mg with a solution of sodium chloride in a volume of 100-150 ml.
Droppers for children are put only as a last resort. The daily dosage for babies up to 3 months should not exceed 60 mg. For older children, the drug is given in a dose corresponding to 2-3 mg per kilogram of the child's weight.
A single dose of aminophylline for adults should not exceed 250 mg. In the maximum dose, the drug can be administered no more than 2 times a day.
The duration of treatment with the help of injections should not exceed 2 weeks. As soon as the patient's condition improves, it is recommended to transfer it to oral medications.
Non-traditional application of "Euphyllin"
According to the manufacturer's instructions, the drug "Eufillin" with bronchitis should be used as a peroral medicine, as well as for injection or drip administration in cases of acute bronchial obstruction. Electrophoresis with "Euphilin" is used mainly for the treatment of bronchial asthma and osteochondrosis, in cases of cerebral circulation disorders, to reduce intracranial pressure, and to relieve tension of smooth muscles, but this procedure is not mentioned in the manual for bronchitis.
Nevertheless, such treatment of bronchitis is also actively practiced among doctors. For electrophoresis, use an ampoule solution of the drug, which moistens the tissue to then apply it on the area of the bronchial tubes between the body of the patient and the electrode.
With bronchitis, "Eufillin" can be used alone or in combination with magnesia. In the second case, one napkin is wetted in a solution of "Eufillina", and the other is impregnated with magnesium, after which the napkins are put under the electrodes with different poles.
The medicine passes through the skin under the influence of an electric current, the strength of which is selected individually. Thus, aminophylline is supplied directly to the bronchi, facilitating breathing and facilitating the saturation of blood with oxygen, but without having systemic effects on other organs, which is especially important in the therapy of small patients.
The time of the procedure usually ranges from 10 to 20 minutes (in pediatrics, the time is set to 10 minutes). On average, about 15-20 procedures are performed, which are appointed daily or once every 2 days.
The conventional method for carrying out drug electrophoresis is described above. However, with bronchitis as one of the pathologies of the respiratory organs, good results are also obtained by interstitial electrophoresis, in which the drug is administered orally or parenterally, after which the electrodes are applied to the area of the bronchi.
The introduction of drugs by electrophoresis is painless (for example, intramuscular administration of the drug is accompanied by severe pain) a method of therapy in which even small doses of the drug produce a lasting positive effect, and the bioavailability of aminophylline approaches 100%, which can not be achieved with oral administration.
However, in the appointment of electrophoresis, it is necessary to take into account contra-indications concerning not only the medicine used, but also the procedure itself. Electrophoresis is not performed if the patient is in a serious condition, he has a high body temperature (from 38 degrees), blood coagulability is disrupted, in the presence of pacemakers and other metal-containing implants, if the integrity of the skin at the site of exposure, during menstruation. Do not allow the procedure and health pathologies such as tuberculosis (active form), cancer, liver and kidney failure. The influence of the electromagnetic field is considered dangerous for decompensated cardiovascular failure and severe mental disorders. Electrophoresis is prohibited during the exacerbation of the disease.
Another unconventional way to use "Eufillina" with bronchitis, is the holding of inhalations with the drug. It is difficult to say on what grounds the rationale for such treatment is based. Apparently the property that "Eufillin", getting into the bloodstream, effectively expands the bronchi and alveoli, removing the increased muscle tone of the respiratory tract, led to the erroneous conclusion that the drug will have the same effect, getting on the bronchial mucosa.
Inhalations with "Eufillin" with bronchitis, although they are quite popular, are equal in their effectiveness to the same procedure performed with clean water. This opinion of doctors who argue that the expansion of the bronchi occurs under the influence of steam, rather than the drug itself.
With chronic bronchitis, it is more advisable to talk about a different treatment regimen, when inhalations are carried out with "Berodual" or "Salbutamol" and "Lazolvanom", where the first 2 drugs expand the bronchi, and the latter facilitates the excretion of phlegm. As a variant of inhalation with "Lazolvanom" in bronchitis can be carried out after therapy with "Euphyllinum" and "Suprastin", the reception of which helps to relieve edema and respiratory tract spasms. In this case, antispasmodic and antihistamine are taken orally on the eve of inhalations.
With chronic bronchitis and strong cough, a good effect is shown by medicinal compresses and lotions. But since "Eufillin" does not penetrate well through the skin, it is useless to use it in its pure form. But in combination with the drug "Dimexide", facilitating the penetration of other drugs into the tissues, aminophylline is quite able to alleviate the patient's condition by improving the ventilation of the respiratory system.
"Dimexid" and "Eufillin" in a compress with bronchitis are found in different recipes.
- 1 tbsp. Dimexide,
- 1 ampoule "Eufillina" 5 ml,
- 4 tablespoons water, heated to 45 degrees.
First, mix "Dimexide" with water, then add "Eufillin".
- 1 tbsp. Dimexide,
- 1 ampoule of "Eufillina" and "Mukolvan"
- 5 tablespoons warm water.
The composition is prepared on the same principle.
The compress is done as follows: moisten the tissue tissue in the prepared composition, apply it on the chest or back of the patient, cover with a film and a warm cloth. Hold the compress for 30-40 minutes. You can do it 1 or 2 times a day, as the doctor will appoint.
Applying compresses "Dimexide" is important to realize that this drug has a high toxicity. Applying it in pure form is dangerous even for a healthy person, not to mention people with pathologies of the cardiovascular system, liver and kidneys, to which the medicine is prohibited in any form.
When you are going to apply a compress with Dimexid and Eufillin to treat a child, you should first consult with your doctor about the safe proportions of water and drugs, because Dimexide can be used only from the age of 12, and Eufillin according to the annotation from the 6-year-old.
As for the warming compresses themselves, they can not be done at high body temperature and superimposed on the heart area. After removing the compress, the skin must be wiped with a damp cloth, removing the remnants of the medicine.
Eufillin to children with bronchitis
According to the instructions to the drug "Eufillin" with bronchitis and other pathologies, where rapid withdrawal of spasms and restoration of respiration and circulation are required, it is allowed to apply from the age of 6. However, in pediatric medicine, medication is often used to save the lives of very young patients. So it is changed when the obstruction of the bronchi in newborns, caused by the ingress of respiratory milk and physiological fluids.
Children up to 3 years of age, the drug in the injectable form can be administered only for life indications and only intramuscularly, the tablets are not given to babies at all. If the threat to the life of the child no injection solutions are allowed to enter, only from the age of 14 years. At the age of 3-6 years, a child can be prescribed a drug even in the form of tablets, however, the dosage will be much less than that of an adult.
In children with bronchitis, bronchospasm occurs quite often, which means that emergency help is required to restore breathing. The most effective in this case is considered an intravenous drug, which should be strictly controlled by the attending physician. And in the future it is recommended to leave the child under the supervision of a pediatrician, because "Eufillin" is famous for its influence not only on the bronchi, but also on the cardiovascular system, which can cause a drop in blood pressure against a decrease in the tone of blood vessels and other undesirable consequences.
To avoid negative effects on the children's organism at a young age, the drug is recommended to be used only in the form of inhalations or during physiotherapy. Medicinal electrophoresis avoids the systemic influence of aminophylline on the children's body (the circulatory system, the heart, kidneys, bile ducts, the mucous membrane of the gastrointestinal tract, etc.), since the active substance is delivered directly to the affected area, where it has a therapeutic effect in required safe concentrations.
The effective dose of the drug under various manipulations is calculated by the attending physician, based on the age and weight of the sick child.