Enzimtal

Enzimtal is an enzyme medicine that helps improve digestive processes. This is a comprehensive medication, which includes elements required for the rapid elimination of dyspepsia, as well as control over discomfort in the abdominal area and bloating.

It helps stabilize digestive function and eliminates flatulence with dyspepsia. The drug contains papain and fungal diastasis (contains α-, as well as β-amylase), affecting the same enzymes.

Indications Enzimtala

It is used to eliminate signs of bloating and dyspepsia.

Release form

The release of drugs is made in the form of dragees - 10 pieces inside the strip; inside a pack - 1 or 10 such strips.

Pharmacodynamics

Fungal diastasis helps to improve the digestibility of food that contains large amounts of carbohydrates. It is an amylolytic enzyme with a specific effect on the transformation of starch into maltose with dextrose. The lack of this enzyme leads to a slowdown in hydrolysis and the formation of the CO2 element (which causes discomfort inside the abdomen). The intensity of the amylolytic effect of the fungal distase, which is contained inside the medicinal dragee, is equal to 1–1200 (1-part of the element splits 1200 components of boiled starch that comes with food).

Papain is a component that is of plant origin. It is a mixture of enzymes, which is obtained from the juice of the uncropped fruits of Carica Papaya, includes papain with chymopapain and has an extensive proteolytic effect. It can be used in people with reduced or preserved gastric activity aimed at producing acid.

The complex effect exerted by the enzyme enzymes Enzymtal has a stronger intensity than the effect each of them has individually.

Simethicone is an inert surface element that does not have toxic properties; It has a defoamer effect. The basis of the substance is silicon. Due to the influence of this substance, intestinal gas formation is reduced. Its action develops with a decrease in the surface tension of gas bubbles that form inside the intestine during swelling. The released gas is absorbed or discharged naturally. The substance does not alter the secretory function of the stomach and the absorption of food components. Simethicone reduces the pain associated with severe swelling, and the severity of flatulence, and in addition significantly improves the condition in the case of aerophagia, bloating and absorption disorders, digestion and excretion. All this allows the specified element is useful to supplement the enzyme components of the drug.

Activated carbon is enterosorbent. It has extensive surface effects, as well as the ability to adsorb alkaloids with gases, exo- and endotoxins, and other chemical ligaments. The substance has a detoxifying and enterosorbent effect, helps adsorb toxins and gases that appear during digestive disorders, adsorbs poorly soluble elements and reduces the volume of intestinal contents. As a result, it helps to alleviate the condition in the case of dyspepsia and flatulence, providing a combined (along with enzymes) effect.

Nicotinamide is involved in carbohydrate metabolism in the form of coenzyme. Nicotinamide coenzymes (NAD with NADP) are very important for the functioning of all cells. They are necessary for respiration of tissues (it is the first link of the respiratory chain) and cellular energy exchange. A deficiency of nicotinamide is mainly noted in the case of an unbalanced diet regime in the elderly. The lack of an element causes a decrease in gastric acid, which causes changes in intestinal absorption and digestion; In addition, such a deficiency can provoke hypolactasia, which often acts as the basis for the appearance of diarrhea.

Pharmacokinetics

The active elements of Enzymtal are released inside the stomach after half an hour from the moment of oral administration of the drug, after which their interaction with food begins.

Papain with fungal diastase, as well as activated carbon and simethicone are not absorbed after oral administration.

Only nicotinamide undergoes absorption inside the gastrointestinal tract. Absorption can be impaired in the case of enteritis, ulcers, or lack of acid inside the stomach. Nicotinamide passes inside all tissues and is excreted unchanged through the kidneys or after intrahepatic transformation (mainly in the element methylnicotinamide).

Dosing and administration

For adolescents over the age of 14 and adults, the portion is 2 tablets 3 times a day (with meals). A child aged 7-14 years old should be consumed along with food on the 1st tablet, 3 times a day.

Drops swallowed whole, without chewing, squeezed with plain water.

The duration of the treatment cycle is personally selected by the doctor, taking into account the course of the pathology.

Use Enzimtala during pregnancy

You can not use the drug for HB or pregnancy.

Contraindications

Among the contraindications:

• severe intolerance caused by the effects of drug elements;
• intestinal blockage, the presence of bleeding or ulcers inside the gastrointestinal tract;
• diseases affecting the digestive system and having an obstructive nature;
• hepatic dysfunction;
• due to the presence of aspartame in the composition of the drug, it is prohibited to use it in persons with phenylketonuria.

Side effects Enzimtala

Side effects that occur under the influence of nicotinamide:

• possible development of symptoms of allergy in the form of epidermal hyperemia, rash (spotted, penile or urticaria), as well as, occasionally, itching, idiosyncratic effects or intolerance;
• the use of high portions leads to the development of nausea, abdominal pain, diarrhea, vomiting and aggravation of ulcers in the gastrointestinal tract; In addition, epidermal dryness, sensation of heat in the extremities, arrhythmia, a decrease in blood pressure, short headache and prediabetes can occur.

Disorders related to activated carbon:

• nausea, obstipation, vomiting, or diarrhea may occur;
• long-term use of drugs can cause a lack of hormones, proteins with vitamins and fat, in which it is necessary to carry out appropriate drug correction.

Overdose

When nicotinamide poisoning may cause nausea or vomiting and pain in the abdominal area, as well as potentiation of peristalsis.

Gastric lavage and appropriate symptomatic action must be performed.

Interactions with other drugs

Activated carbon is able to weaken the absorption of therapeutic substances inside the gastrointestinal tract in the case of such a combination. Because of this, other drugs must be consumed 2 hours before or after 1 hour after the introduction of Enzymtal.

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Storage conditions

Enzymtal is required to be kept in a place closed to children. Temperature indicators - no more than 25 ° C.

Shelf life

Enzimtal can be applied within a 2-year period from the moment the therapeutic product is manufactured.

Application for children

Enzimtal forbidden to appoint persons under the age of 7 years.

Analogs

Analogues of the medication are the substances Pankreazim, Ajizim with Creasim, Pangrol and Creon with Somilaza, and in addition, Unianzyme with Mezim Forte, Pancreatin and Digestin. Also on the list are Panzinorm, Enzistal, Festal with Hermital, Penzital and Mikrasim.