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Last reviewed: 19.10.2021

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Enterospazmil is a complex medicine that belongs to a group of substances that affect the digestive function and the work of the digestive tract; used to treat digestive activity.

The medication contains phloroglucinol dihydrate (non-atropin-type antispasmodic), as well as simethicone. The drug prevents the accumulation of gases inside the intestines, eliminates stomach cramps (also with bloating) and reduces the rate of peristalsis.[1]

Indications Enterospasmil

It is used in combination therapy during disorders of the digestive function. It is used for smooth muscle spasms, which can also be accompanied by pains of varying severity and bloating of a different nature:

  • flatulence associated with dyspepsia, lesions of the gastrointestinal tract and aerophagia;
  • Botkin's syndrome, the period after surgery, pyloric or cardiospasm and gastritis;
  • colitis, cholecystitis , enteritis, cholangitis, diarrhea, IBS, papillitis, cholecystolithiasis and pericholecystitis.

It is also prescribed for lesions of the urethra and gynecological diseases, against which smooth muscle spasms and flatulence are noted. It can be used during preparation for ultrasound and X-ray procedures.

Release form

The release of the therapeutic agent is realized in the form of capsules, 15 or 30 pieces each inside the box.


Simethicone is an organosilicon-type substance belonging to the group of polydimethylsiloxanes. It has a defoaming effect. Simethicone has no toxic properties, affects the surface tension of gas bubbles that form inside the gastrointestinal tract, destroying them. The gases released during this are released naturally with the intestinal contents through its peristalsis. Some of these gases are also absorbed into the walls of the small intestine.

In gastritis, simethicone exhibits an analgesic effect. Helps stabilize gastric function by improving well-being and digestive processes.[2]

Clinical testing has confirmed a relaxing effect on gastrointestinal smooth muscle. Phloroglucinol dihydrate reduces the rate of excess motor activity in the colon and colon, which typically occurs as a reaction to food intake in people with bowel disorders.[3]


When taken orally, phloroglucinol is absorbed at a high rate and participates in metabolic processes during the 1st intrahepatic passage. Excretion is carried out in the form of metabolic elements, mainly in the urine. The period of reaching the plasma Cmax is 60 minutes. With a Cmax of 2.74 mg / ml, the half-life is 2 hours. The overall level of oral bioavailability is 30%.

Simethicone is not absorbed inside the body; after passing through the gastrointestinal tract, it is excreted unchanged.

Use Enterospasmil during pregnancy

Enterospazmil should not be administered to pregnant or breastfeeding women.


It is contraindicated to use in case of severe intolerance to the active components of the medication or its auxiliary elements, and is also not prescribed in case of obstruction in the gastrointestinal tract or intestinal blockage.

Side effects Enterospasmil

In the case of severe sensitivity, side effects may develop, which are expressed by the following symptoms: dyspeptic disorders (vomiting, xerostomia, nausea) and signs of allergies (itching, rashes, urticaria of an allergic nature).

Dosing and administration

The medication is taken with food or after it, when pain occurs.

For children aged 6-12 years, the serving size is 1 capsule, with 3 times per day. For adolescents from 12 years old and adults - you need to take 2 capsules of drugs 3 times a day.

In the case of preparation for diagnostic procedures, you need to take 1 capsule the day before performing, 2 times a day, and then in the morning on the day of the study, another 1 capsule.

It is allowed to use no more than 6 capsules per day. The recommended serving must not be exceeded during treatment. The duration of therapy is selected by the attending physician.

With the development of negative symptoms not noted in the instructions, as well as the absence of a result after using Enterospazmil for a period of 2 days, you need to consult a doctor.

  • Application for children

The medication should not be prescribed to children under the age of 6.


In case of poisoning, symptomatic procedures must be performed. The medication is canceled, gastric lavage is performed and the use of sorbents is prescribed.

Interactions with other drugs

The combination of fluroglucinol with powerful analgesics, including morphine or its derivatives, should be abandoned, since this can provoke the development of spasmodic effects.

Storage conditions

Enterospazmil should be kept at a temperature of no more than 25 ° C.

Shelf life

Enterospazmil can be used for 24 months from the date of manufacture of the therapeutic product.


The analogues of the medicine are the drugs Spascuprel, Iberogast and Gastritol with Dill fragrant with fruits, and in addition Gastrokind and Enterokind. The list also includes Caraway fruits, Hilak and Fennel fruits.


To simplify the perception of information, this instruction for use of the drug "Enterospasmil" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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