Energetic

Vigor has an impact by stabilizing the activity of the cell walls, as well as accelerating the recovery of functional liver cells (hepatocytes). The drug slows down lipid oxidation inside the liver tissues, as well as the conversion to peroxide compounds.

The active elements of the drug are defatted and enriched soy type phospholipids. In the process of excretion of phospholipids through the HDV, there is a decrease in the lithogenic index and stabilization of bile indicators.

[1],

Indications Energetic

It is used in the following disorders:

• hepatitis in the active or chronic phase;
• hepatic degeneration of a fatty character (this includes liver damage developing in diabetes);
• provoked by hepatosis poisoning (industrial poisons, alcohol, drugs, toxins, as well as unhealthy diets);
• postoperative therapy in the case of surgery in the liver or GIB;
• mild hypercholesterolemia, with the ineffectiveness of the diet or other methods of non-drug therapy.

[2], [3], [4]

Release form

The release of the drug component is in the form of capsules. Inside the pack - 10, 30 or 50 pieces.

[5]

Pharmacodynamics

Soybean phospholipids have an intense hepatoprotective effect: they can significantly weaken fatty hepatic degeneration, inhibit the growth of connective tissues inside the hepatic parenchyma, and in addition reduce cholesterol levels due to their strong hypocholesterolemic effect. Also phospholipids inhibit the binding of collagen.

At the same time, these high-energy compounds affect the disturbed lipid metabolism, regulating metabolic processes. As a result, cholesterol with neutral fats are converted into forms that can be moved (especially due to the increased ability of HDL to add cholesterol), and then undergo oxidative processes.

[6], [7], [8], [9]

Pharmacokinetics

After ingestion, the main part of the drug is absorbed inside the small intestine, and then splits as a result of the influence of the enzyme phospholipase-A with the formation of the component 1-acyl-lyso-phosphatidylcholine. At the same time, 50% of this component is immediately converted into phosphatidylcholine of a polyunsaturated nature, which is able to penetrate the blood through the lymphatic ducts, and later, mainly in combination with HDL, move inside the liver. Blood values of Cmax phosphatidylcholine after 6 hours and one more day from the moment of ingestion, on average equal to 20%.

The term half-life of a choline element is 66 hours, and unsaturated fatty acids - 32 hours.

[10], [11], [12], [13], [14], [15]

Dosing and administration

The medication should be prescribed for ingestion - the capsules are swallowed, washed down with plain water (1 cup). You need to use 2 capsules 3 times a day. Chewing capsules is prohibited.

The therapeutic cycle is selected personally by the attending doctor, based on the nature and severity of the pathology.

Use Energetic during pregnancy

As a food product, soy in pregnancy is not dangerous, but the experience of using enriched low-fat phospholipids from soy during the specified period, as well as during lactation, is very limited, which is why it is not necessary to designate Enerive during these periods.

Contraindications

Among the contraindications:

• severe intolerance associated with peanuts or soybean phospholipids;
• history of antiphospholipid syndrome.

[16], [17], [18]

Side effects Energetic

The main side signs are:

• epigastric discomfort or diarrhea;
• allergy symptoms;
• the appearance of hemorrhages (in women during the intermenstrual gap).

[19], [20], [21], [22]

Interactions with other drugs

Synergism with coumarin anticoagulants (warfarin or fenprocumon) may occur, which is why with such combinations you need to adjust the dose of drugs.

[23], [24], [25], [26],

Storage conditions

It is required to keep energetically in a closed place from small children. Temperature indicators - not higher than 25 ° С.

[27], [28], [29], [30], [31], [32]

Shelf life

It can be used vigorously within a 24-month term from the time the drug was manufactured.

[33]

Application for children

The drug is forbidden to use in persons younger than 12 years.

[34]

Analogs

Analogues of drugs are means Galstena and Antral with Kars.

[35], [36], [37],

Reviews

Vigorously receives mostly good reviews from medical specialists, but it is noted that it is possible to eliminate violations related to the liver only when using drugs in combination with diet and other medications.

Patients who used the drug, note that it has a high therapeutic efficacy. Of the minuses, a rather long treatment course lasts for about 3 months.

[38], [39], [40], [41], [42]