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Econazole
Last reviewed: 03.07.2025

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Indications Econazole
It is indicated for the treatment of dermatomycosis on the feet, as well as smooth skin, as well as versicolor lichen, cutaneous candidiasis, nail infections and mycoses.
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Pharmacodynamics
Econazole is an antifungal agent belonging to the group of imidazole derivatives. It has a wide range of antibacterial and antifungal effects.
The drug acts by inhibiting the processes of ergosterol biosynthesis, as well as changing the lipid structure of fungal membranes. It has a bactericidal and fungicidal effect. It actively affects dermatophytes (such as Trichophyton, Epidermophyton and Microsporum), yeast (Candida, Pityrosporum spp., Malassezia furfur, and Rhodotorula spp.), mold fungi (Aspergillus, Scopulariopsis brevicaulis and Cladosporium spp.), and at the same time, individual gram-positive microbes (Strepto- and Staphylococci, as well as Nocardia minutissima).
Use Econazole during pregnancy
There have been no tests regarding the use of the gel during pregnancy. Since systemic absorption of the drug is observed, it is not recommended to prescribe it to pregnant women.
There is no information on whether econazole nitrate passes into breast milk, so it is allowed to use it during lactation only if the possible benefit to the patient outweighs the risk of side effects to the fetus. Applying the gel to areas around the nipples and the nipples themselves is prohibited.
Side effects Econazole
The use of the gel may cause the following side effects: hypersensitivity, urticaria, contact dermatitis, skin rashes, as well as blisters, dryness, hyperemia and irritation of the skin. Also itching and burning, as well as tingling and pain, Quincke's edema, skin atrophy, hypopigmentation and exfoliative changes in the skin.
Interactions with other drugs
Systemic exposure to econazole inhibits the CYP3A/2C29 enzyme, but since the drug is poorly absorbed into the systemic circulation, the potential for significant clinical interactions is extremely low.
Patients taking oral anticoagulants (acenocoumarol or warfarin) need to closely monitor their blood clotting parameters.
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Storage conditions
Store in the original tube under standard conditions for medicinal products, in a place inaccessible to small children. Temperature – no more than 25 0 C.
Shelf life
Econazole is suitable for use for 2 years from the date of manufacture of the gel.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Econazole" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.