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Last reviewed by: Aleksey Portnov , medical expert, on 13.03.2019

Deprim is an antidepressant medicine.

Indications of the deprima

It is used for a chronic feeling of fatigue, a depressed mood, emotional exhaustion, and a decline in physical strength. In addition, the drug is used if performance deteriorates.

Release form

Release in tablets, 10 pieces inside a blister pack. In a separate pack - 3 blister plates.

Deprim forte - a capsule, 10 pieces inside the blister, 2 blister packs inside the pack.

Used for reduced mood, hypersensitivity to weather changes, as well as for mild or moderate depressions, against which there is a sense of anxiety (among them also associated with menopause).


St. John's wort extract, which contains such components as hyperforin with pseudo-hypericin and hypericin, has a harmonizing effect on the VNS, as well as the CNS.

Deprim is effective in apathy and low mood, against which there are such manifestations as loss of appetite, a feeling of indisposition, and insomnia. The drug improves mood, and at the same time positively affects the physical condition and mental abilities. Helps also improve performance. 

Use of the deprima during pregnancy

There is no information on the safety of use of drugs during pregnancy or lactation, therefore, it is not recommended to take Decim during these periods.


The main contraindications:

  • hypersensitivity to the components of drugs;
  • severe forms of depression, in which there are thoughts of suicide;
  • children's age is less than 6 years.

Side effects of the deprima

The use of the drug can cause the appearance of such adverse reactions (they occur only occasionally and are short-lived):

  • reactions of the organs of the National Assembly: occasionally there are headaches or dizziness;
  • manifestations in the gastrointestinal tract: occasionally develop disorders of the gastrointestinal tract, as well as dry mouth of the mucous membranes;
  • dermatological disorders and reactions from the subcutaneous layer: single (in people with hypersensitivity to sunlight), when burned in the sun, burns may occur;
  • systemic disorders: occasionally fatigue develops;
  • Immune disorders: occasionally there are manifestations of dermatological type allergy - itching and redness of the skin;
  • mental illness: occasionally there is a feeling of anxiety or anxiety. There is a single increase in the likelihood of the appearance of a manic condition (in people with bipolar depression).

Dosing and administration

For adolescents from 12 years and adults: taking the 1st tablet three times a day.

Children 6-12 years of age, the medicine is allowed to be consumed exclusively under the supervision of the doctor - in the amount of 1-2 tablets per day (in the morning or at lunch). For a day of this category of treated, you can take no more than 2 tablets.

The medicine is consumed with food, while washing with water.

Positive impact occurs in the period of 10-14 days. A stable drug result is manifested in the case of a constant use of medicines in the period of several weeks or months.

If there is no improvement after 4-6 weeks from the start of the course, it is necessary to cancel the medication and consult the treating doctor.


There were no cases of acute intoxication with St. John's wort medicine.

If the drug is overdosed, the patient should avoid exposure to the sun, as well as irradiation with UV rays during 1-2 weeks.

Interactions with other drugs

Drugs that contain St. John's wort extract can increase the activity of a large number of enzymes that participate in the metabolism of drugs. As a result of such reactions, a decrease in plasma indices can be observed, as well as a weakening of the drug efficacy of individual drugs (such as cyclosporin with indinavir, warfarin with digoxin, and theophylline and contraceptive drugs).

Due to the drug interaction with the derivatives of tryptane (among them sumatriptan with zolmitriptan and naratriptan), and in addition to antidepressants (especially SSRIs - such as fluvoxamine, sertraline and citalopram with paroxetine and fluoxetine), potentiation of negative serotonin reactions occurs .

In addition to the aforementioned drugs, Deprim is also able to interact with other drugs that are metabolized by enzymes of the hemoprotein P 450 system.

Influence on enzymes can be carried out and after the abolition of drugs, which contain extract of St. John's wort. Because of this, Deprim is able to interact with other medicines for about another 2 weeks after the end of its use.

With prolonged use of the drug along with other drugs (more than the first week) with the subsequent completion of the course, it is necessary to take into account the fact that there is a possibility of negative effects of drugs taken in combination with Deprim.

For the period of therapy it is necessary to refrain from drinking alcohol.

Storage conditions

Decrement must be kept out of the reach of children. Temperature indices - not more than 25 ° С.

Shelf life

Decision is allowed to be used in the period of 2 years from the date of manufacture of the medicinal product.

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To simplify the perception of information, this instruction for use of the drug "Deprim" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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