Medical expert of the article
New publications
Preparations
Deprim
Last reviewed: 03.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Deprim is an antidepressant drug.
[ 1 ]
Release form
Released in tablets, 10 pieces inside a blister pack. In a separate pack - 3 blister plates.
Deprim forte is capsules, 10 pieces inside a blister, 2 blister strips inside a pack.
It is used for low mood, hypersensitivity to weather changes, as well as mild or moderate depressions, which are accompanied by a feeling of anxiety (including those associated with menopause).
Pharmacodynamics
St. John's wort extract, which contains such components as hyperforin with pseudohypericin and hypericin, has a harmonizing effect on the autonomic nervous system, as well as the central nervous system.
Deprim is effective in cases of apathy and low mood, which are accompanied by symptoms such as loss of appetite, feeling of malaise, and insomnia. The medicine helps improve mood, and at the same time has a positive effect on physical condition and mental abilities. It also helps improve performance.
Dosing and administration
For adolescents aged 12 years and over and adults: take 1 tablet three times a day.
Children aged 6-12 years are allowed to take the medicine only under the supervision of a doctor - in the amount of 1-2 tablets per day (in the morning or at lunch). This category of patients can take no more than 2 tablets per day.
The medicine is taken with food and washed down with water.
The positive effect occurs within 10-14 days. A stable medicinal result is manifested in the case of constant use of the drug for a period of several weeks or months.
If there is no improvement after 4-6 weeks from the start of the course, you should stop taking the medication and consult your doctor.
Use Deprima during pregnancy
There is no information on the safety of using the drug during pregnancy or lactation, therefore it is not recommended to take Deprim during these periods.
Contraindications
Main contraindications:
- hypersensitivity to the components of the drug;
- severe forms of depression, in which thoughts of suicide are observed;
- children under 6 years of age.
[ 6 ]
Side effects Deprima
The use of the drug may cause the following side effects (they occur only occasionally and are short-lived):
- reactions of the nervous system: headaches or dizziness occasionally occur;
- manifestations in the gastrointestinal tract: gastrointestinal disorders occasionally develop, as well as dryness of the oral mucosa;
- dermatological disorders and reactions from the subcutaneous layer: isolated cases (in people with hypersensitivity to sunlight) when exposed to the sun, burns may occur;
- systemic disorders: fatigue occasionally develops;
- immune disorders: occasionally, manifestations of dermatological allergies are observed - itching and redness of the skin;
- mental illness: a feeling of restlessness or anxiety occasionally appears. An increased likelihood of developing a manic state is occasionally noted (in people with bipolar depression).
Overdose
There have been no cases of acute intoxication with St. John's wort preparations.
In case of overdose of the drug, the patient must avoid exposure to the sun and UV rays for a period of 1-2 weeks.
Interactions with other drugs
Medicines containing St. John's wort extract are capable of increasing the activity of a large number of enzymes involved in the processes of drug metabolism. As a result of such reactions, a decrease in plasma indices may be observed, as well as a weakening of the medicinal effectiveness of individual drugs (such as cyclosporine with indinavir, warfarin with digoxin, as well as theophylline and contraceptive drugs).
Due to the drug interaction of the drug with triptan derivatives (including sumatriptan with zolmitriptan and naratriptan), as well as with antidepressants (especially SSRIs such as fluvoxamine, sertraline and citalopram with paroxetine and fluoxetine), there is a potentiation of negative serotonin reactions.
In addition to the above-mentioned drugs, Deprim can interact with other drugs that are metabolized by enzymes of the hemoprotein P 450 system.
The effect on enzymes can also occur after discontinuing medications containing St. John's wort extract. Because of this, Deprim can interact with other medications for approximately 2 weeks after stopping its use.
When using the drug for a long time together with other drugs (more than 1 week) with subsequent completion of the course, it is necessary to take into account the possibility of negative effects of the drug taken in combination with Deprim.
During the period of therapy, it is necessary to abstain from drinking alcohol.
Storage conditions
Deprim should be kept out of reach of children. Temperature indicators – no more than 25°С.
Shelf life
Deprim is allowed to be used for a period of 2 years from the date of manufacture of the drug.
Attention!
To simplify the perception of information, this instruction for use of the drug "Deprim" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.